(Q46204578)

20 December 2017

title

Structure-guided mutational analysis reveals the functional requirements for product specificity of DOT1 enzymes (English)

1 reference

20 December 2017

Histone-lysine N-methyltransferase, H3 lysine-76 specific

main subject

1 reference

5 February 2019

1 reference

Gülcin Dindar

1

1 reference

20 December 2017

Andreas M Anger

2

1 reference

20 December 2017

Christine Mehlhorn

3

1 reference

20 December 2017

Sandra B Hake

4

1 reference

20 December 2017

Christian J Janzen

5

1 reference

20 December 2017

language of work or name

English

0 references

publication date

12 November 2014

1 reference

20 December 2017

published in

Nature Communications

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20 December 2017

volume

5

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20 December 2017

page(s)

5313

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20 December 2017

Crystal structure of the nucleosome core particle at 2.8 A resolution

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The many faces of histone lysine methylation

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The diverse functions of histone lysine methylation

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SET domain proteins modulate chromatin domains in eu- and heterochromatin.

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The SET-domain protein superfamily: protein lysine methyltransferases

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Structural and sequence motifs of protein (histone) methylation enzymes

21 January 2018

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The diverse functions of Dot1 and H3K79 methylation.

21 January 2018

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Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain

21 January 2018

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Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase.

21 January 2018

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Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association

21 January 2018

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Dot1p modulates silencing in yeast by methylation of the nucleosome core

21 January 2018

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Structure of the catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase

21 January 2018

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Structure of the conserved core of the yeast Dot1p, a nucleosomal histone H3 lysine 79 methyltransferase

21 January 2018

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Structure and catalytic mechanism of a SET domain protein methyltransferase

21 January 2018

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Structure of the Neurospora SET domain protein DIM-5, a histone H3 lysine methyltransferase

21 January 2018

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Crystal structure and functional analysis of the histone methyltransferase SET7/9

21 January 2018

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Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet

21 January 2018

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Structural origins for the product specificity of SET domain protein methyltransferases

21 January 2018

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SET7/9 Catalytic Mutants Reveal the Role of Active Site Water Molecules in Lysine Multiple Methylation

21 January 2018

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DOT1A-dependent H3K76 methylation is required for replication regulation in Trypanosoma brucei

21 January 2018

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The histone methyltransferase Dot1/DOT1L as a critical regulator of the cell cycle

21 January 2018

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Methylation of histone H3 on lysine 79 associates with a group of replication origins and helps limit DNA replication once per cell cycle

21 January 2018

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A histone methyltransferase modulates antigenic variation in African trypanosomes.

21 January 2018

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The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure

21 January 2018

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Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation

21 January 2018

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Ubiquitination of histone H2B by Rad6 is required for efficient Dot1-mediated methylation of histone H3 lysine 79.

21 January 2018

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Heterologous expression reveals distinct enzymatic activities of two DOT1 histone methyltransferases of Trypanosoma brucei

21 January 2018

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Nonprocessive methylation by Dot1 leads to functional redundancy of histone H3K79 methylation states

21 January 2018

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Many paths to methyltransfer: a chronicle of convergence

21 January 2018

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Structural basis for the product specificity of histone lysine methyltransferases

21 January 2018

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Structural insights into protein arginine symmetric dimethylation by PRMT5

21 January 2018

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How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers

21 January 2018

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Expression and purification of recombinant histones and nucleosome reconstitution

21 January 2018

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Preparation of nucleosome core particle from recombinant histones

21 January 2018

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Characterization of two different Asf1 histone chaperones with distinct cellular localizations and functions in Trypanosoma brucei

21 January 2018

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The HHpred interactive server for protein homology detection and structure prediction

21 January 2018

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Protein homology detection by HMM-HMM comparison

21 January 2018

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Jalview Version 2--a multiple sequence alignment editor and analysis workbench

21 January 2018

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Protein structure modeling with MODELLER

21 January 2018

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21 January 2018

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21 January 2018

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Toward the estimation of the absolute quality of individual protein structure models

21 January 2018

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21 January 2018

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Chromatin silencing protein and pachytene checkpoint regulator Dot1p has a methyltransferase fold

21 January 2018

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Selective di- or trimethylation of histone H3 lysine 76 by two DOT1 homologs is important for cell cycle regulation in Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6313

inferred from DOI database lookup

7 January 2021

based on heuristic

New DNA sequence rules for high affinity binding to histone octamer and sequence-directed nucleosome positioning

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6313

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCOMMS6313

1 reference

20 December 2017

ADS bibcode

2014NatCo...5.5313D

0 references

1 reference

20 December 2017