(Q46215386)

20 December 2017

title

Designing CD4 immunoadhesins for AIDS therapy. (English)

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20 December 2017

author name string

Capon DJ

1

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20 December 2017

Chamow SM

2

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20 December 2017

Mordenti J

3

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20 December 2017

Marsters SA

4

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20 December 2017

Gregory T

5

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20 December 2017

Mitsuya H

6

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20 December 2017

Byrn RA

7

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20 December 2017

Lucas C

8

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20 December 2017

Wurm FM

9

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20 December 2017

Groopman JE

10

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20 December 2017

language of work or name

English

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publication date

1 February 1989

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20 December 2017

published in

Nature

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20 December 2017

volume

337

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20 December 2017

issue

6207

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20 December 2017

page(s)

525-531

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20 December 2017

https://scigraph.springernature.com/pub.10.1038/337525a0

exact match

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cites work

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Human immunodeficiency virus type 1 challenge of chimpanzees immunized with recombinant envelope glycoprotein gp120

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Failure of a human immunodeficiency virus (HIV) immune globulin to protect chimpanzees against experimental challenge with HIV

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Variable and conserved neutralization antigens of human immunodeficiency virus

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Strategies for antiviral therapy in AIDS.

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Blocking of HIV-1 infectivity by a soluble, secreted form of the CD4 antigen

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The CD4 antigen: physiological ligand and HIV receptor

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7 January 2021

Accessories or coreceptors?

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7 January 2021

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

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7 January 2021

T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

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7 January 2021

The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain

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7 January 2021

Binding of HTLV-III/LAV to T4+ T cells by a complex of the 110K viral protein and the T4 molecule

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7 January 2021

HIV infection is blocked in vitro by recombinant soluble CD4.

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7 January 2021

A soluble CD4 protein selectively inhibits HIV replication and syncytium formation

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7 January 2021

A soluble form of CD4 (T4) protein inhibits AIDS virus infection

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7 January 2021

Soluble CD4 molecules neutralize human immunodeficiency virus type 1.

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7 January 2021

A soluble recombinant polypeptide comprising the amino-terminal half of the extracellular region of the CD4 molecule contains an active binding site for human immunodeficiency virus

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7 January 2021

Analysis of host-virus interactions in AIDS with anti-gp120 T cell clones: effect of HIV sequence variation and a mechanism for CD4+ cell depletion

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7 January 2021

Interaction between CD4 and class II MHC molecules mediates cell adhesion

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7 January 2021

The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family.

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7 January 2021

Peptide and nucleotide sequences of rat CD4 (W3/25) antigen: evidence for derivation from a structure with four immunoglobulin-related domains

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7 January 2021

Man versus beast: pharmacokinetic scaling in mammals

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7 January 2021

Immunoglobulin G: functional sites

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7 January 2021

The binding site for C1q on IgG

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7 January 2021

Localization of the binding site for the human high-affinity Fc receptor on IgG.

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Binding of complement subcomponent Clq to mouse IgGl, IgG2a AND IgG2b: A novel Clq binding assay

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7 January 2021

Immunoglobulin flexibility in complement activation.

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7 January 2021

Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDS

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7 January 2021

Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides

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7 January 2021

Antibody-enhanced infection by HIV-1 via Fc receptor-mediated entry

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7 January 2021

The role of mononuclear phagocytes in HTLV-III/LAV infection

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7 January 2021

Immunologic abnormalities in the acquired immunodeficiency syndrome

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7 January 2021

Detection of lymphocytes expressing human T-lymphotropic virus type III in lymph nodes and peripheral blood from infected individuals by in situ hybridization

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7 January 2021

HIV is Not the Cause of AIDS

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7 January 2021

AIDS retrovirus induced cytopathology: giant cell formation and involvement of CD4 antigen

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7 January 2021

Role of the HTLV-III/LAV envelope in syncytium formation and cytopathicity

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7 January 2021

Shedding and interspecies type sero-reactivity of the envelope glycopolypeptide gp120 of the human immunodeficiency virus

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7 January 2021

HIV-1-infected T cells show a selective signaling defect after perturbation of CD3/antigen receptor

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7 January 2021

Lymphocyte activation by HIV-1 envelope glycoprotein

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7 January 2021

Human T-cell lymphotropic virus IIIB glycoprotein (gp120) bound to CD4 determinants on normal lymphocytes and expressed by infected cells serves as target for immune attack

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7 January 2021

T cells can present antigens such as HIV gp120 targeted to their own surface molecules

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7 January 2021

Phenotypic heterogeneity of cerebrospinal fluid-derived HIV-specific and HLA-restricted cytotoxic T-cell clones

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7 January 2021

The nucleotide sequence of a human immnnoglobulin Cγlgene

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7 January 2021

Oligonucleotide-directed mutagenesis using M13-derived vectors: an efficient and general procedure for the production of point mutations in any fragment of DNA.

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7 January 2021

Regulation of mRNA accumulation by a human immunodeficiency virus trans-activator protein

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7 January 2021

Delineation of a region of the human immunodeficiency virus type 1 gp120 glycoprotein critical for interaction with the CD4 receptor

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7 January 2021

Identifiers

DOI

10.1038/337525A0

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20 December 2017

Dimensions Publication ID

1048319402

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20 December 2017