(Q46245004)

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Tryptase activates phosphatidylinositol 3-kinases proteolytically independently from proteinase-activated receptor-2 in cultured dog airway smooth muscle cells

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Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/16155087

Tryptase activates phosphatidylinositol 3-kinases proteolytically independently from proteinase-activated receptor-2 in cultured dog airway smooth muscle cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/16155087

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author name string

James K Brown

1

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/16155087

Morley D Hollenberg

2

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/16155087

Cary A Jones

3

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/16155087

publication date

9 September 2005

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/16155087

American Journal of Physiology - Lung Cellular and Molecular Physiology

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/16155087

290

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/16155087

2

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/16155087

L259-69

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/16155087

3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Enhanced phosphorylation of p53 by ATM in response to DNA damage

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Identification of a thrombin sequence with growth factor activity on macrophages

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Human mast cells stimulate vascular tube formation. Tryptase is a novel, potent angiogenic factor

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Dual regulation of Akt/protein kinase B by heterotrimeric G protein subunits

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Mast-cell infiltration of airway smooth muscle in asthma.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Interleukin-4 and -13 expression is co-localized to mast cells within the airway smooth muscle in asthma

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

The CXCL10/CXCR3 Axis Mediates Human Lung Mast Cell Migration to Asthmatic Airway Smooth Muscle

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Mast cell tryptase activates extracellular-regulated kinases (p44/p42) in airway smooth-muscle cells: importance of proteolytic events, time course, and role in mediating mitogenesis

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Airway remodeling and repair.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

The phosphoinositide 3-kinase pathway

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Glycosylation and the activation of proteinase-activated receptor 2 (PAR(2)) by human mast cell tryptase

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Restricted ability of human mast cell tryptase to activate proteinase-activated receptor-2 in rat aorta

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Glycosylation of human proteinase-activated receptor-2 (hPAR2): role in cell surface expression and signalling

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Differential DNA synthesis in response to activation of protease-activated receptors on cultured guinea-pig tracheal smooth muscle cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Protease-activated receptor 2: activation, signalling and function

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Protease-activated receptors start a family

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Matrix metalloproteinase expression and activity in human airway smooth muscle cells.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

LY294002, but not wortmannin, increases intracellular calcium and inhibits calcium transients in bovine and human airway smooth muscle cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Phosphoinositide kinases

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Proliferative action of mast-cell tryptase is mediated by PAR2, COX2, prostaglandins, and PPARgamma : Possible relevance to human fibrotic disorders

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Regulation of hepatic stellate cell proliferation and collagen synthesis by proteinase-activated receptors

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Synovial procollagenase activation by human mast cell tryptase dependence upon matrix metalloproteinase 3 activation

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Synergistic actions of a thrombin-derived synthetic peptide and a thrombin receptor-activating peptide in stimulating fibroblast mitogenesis

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

A dual thrombin receptor system for platelet activation

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Tyrosine 508 of the 85-kilodalton subunit of phosphatidylinositol 3-kinase is phosphorylated by the platelet-derived growth factor receptor

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Luminal trypsin may regulate enterocytes through proteinase-activated receptor 2.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Matrix metalloproteinase stromelysin-1 triggers a cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and a premalignant phenotype in mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Interactions of mast cell tryptase with thrombin receptors and PAR-2.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Trypsin activates pancreatic duct epithelial cell ion channels through proteinase-activated receptor-2.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Ethanol-withdrawal seizures are controlled by tissue plasminogen activator via modulation of NR2B-containing NMDA receptors

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Human beta-tryptase is a ring-like tetramer with active sites facing a central pore

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Mast cells and tumour angiogenesis: the tumor-mediated release of an endothelial growth factor from mast cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Mast cell tryptase is a mitogen for cultured fibroblasts

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Mechanisms of protease-activated receptor-4 actions in cardiomyocytes. Role of Src tyrosine kinase

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Tryptase: a mast cell serine protease

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

A regulatory role for cAMP in phosphatidylinositol 3-kinase/p70 ribosomal S6 kinase-mediated DNA synthesis in platelet-derived-growth-factor-stimulated bovine airway smooth-muscle cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Mast cell tryptases and airway remodeling

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Proteinase-activated receptor (PAR)-1 and -2 agonists induce mediator release from mast cells by pathways distinct from PAR-1 and PAR-2.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

LY-294002 [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] affects calcium signaling in airway smooth muscle cells independently of phosphoinositide 3-kinase inhibition

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Protease-activated receptor (PAR)-independent growth and pro-inflammatory actions of thrombin on human cultured airway smooth muscle

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Proteinase-activated receptor 2 (PAR2)-activating peptides: identification of a receptor distinct from PAR2 that regulates intestinal transport

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Mitogenic signaling pathways in airway smooth muscle

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00215.2005

21 January 2018

Identifiers

10.1152/AJPLUNG.00215.2005

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/16155087

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/16155087

ResearchGate publication ID

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