(Q46246862)

English

A dipolar cycloaddition reaction to access 6-methyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridines enables the discovery synthesis and preclinical profiling of a P2X7 antagonist clinical candidate.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29211470%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

A Dipolar Cycloaddition Reaction To Access 6-Methyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridines Enables the Discovery Synthesis and Preclinical Profiling of a P2X7 Antagonist Clinical Candidate (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29211470%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

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inferred from title

Christa C Chrovian

1

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5 April 2020

Michael A Letavic

18

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5 April 2020

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Akinola Soyode-Johnson

2

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5 April 2020

Alexander A Peterson

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Christine F Gelin

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Xiaohu Deng

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Curt A Dvorak

6

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5 April 2020

Nicholas I Carruthers

7

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Brian Lord

8

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Ian Fraser

9

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Leah Aluisio

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Kevin J Coe

11

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Brian Scott

12

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Tatiana Koudriakova

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5 April 2020

Freddy Schoetens

14

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5 April 2020

Kia Sepassi

15

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5 April 2020

David J Gallacher

16

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5 April 2020

Anindya Bhattacharya

17

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20 December 2017

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5 April 2020

Journal of Medicinal Chemistry

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61

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1

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207-223

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5 April 2020

Identifiers

10.1021/ACS.JMEDCHEM.7B01279

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5 April 2020

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