(Q46256143)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18996846%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

title

The pore domain outer helix contributes to both activation and inactivation of the HERG K+ channel (English)

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26 December 2019

9

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26 December 2019

Guilhem Pages

2

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26 December 2019

Po-Chia Chen

4

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26 December 2019

author name string

Pengchu Ju

1

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26 December 2019

R Peter Riek

3

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26 December 2019

Allan M Torres

5

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26 December 2019

Paramjit S Bansal

6

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26 December 2019

Serdar Kuyucak

7

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26 December 2019

Philip W Kuchel

8

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26 December 2019

language of work or name

English

0 references

publication date

7 November 2008

1 reference

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Journal of Biological Chemistry

26 December 2019

published in

1 reference

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26 December 2019

volume

284

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26 December 2019

issue

2

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26 December 2019

page(s)

1000-1008

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The voltage-gated potassium channels and their relatives

26 December 2019

cites work

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A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

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hERG potassium channels and cardiac arrhythmia

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Drug-induced prolongation of the QT interval

21 January 2018

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HERG K+ channels: friend and foe.

21 January 2018

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Molecular driving forces determining potassium channel slow inactivation

21 January 2018

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Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment

21 January 2018

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The twisted ion-permeation pathway of a resting voltage-sensing domain

21 January 2018

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The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

21 January 2018

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Molecular determinants of gating at the potassium-channel selectivity filter

21 January 2018

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Activation-coupled inactivation in the bacterial potassium channel KcsA.

21 January 2018

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Modulation of K+ current by frequency and external [K+]: a tale of two inactivation mechanisms.

21 January 2018

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The inward rectification mechanism of the HERG cardiac potassium channel

21 January 2018

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Fast inactivation causes rectification of the IKr channel

21 January 2018

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HERG, a Human Inward Rectifier in the Voltage-Gated Potassium Channel Family

21 January 2018

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

21 January 2018

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Evolutionary conservation of both the hydrophilic and hydrophobic nature of transmembrane residues.

21 January 2018

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Identifying nonpolar transbilayer helices in amino acid sequences of membrane proteins

21 January 2018

1 reference

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Recognition of transmembrane helices by the endoplasmic reticulum translocon.

21 January 2018

1 reference

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Structure of the HERG K+ channel S5P extracellular linker: role of an amphipathic alpha-helix in C-type inactivation

21 January 2018

1 reference

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A two-dimensional nuclear Overhauser enhancement (2D NOE) experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromolecules

21 January 2018

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Application of phase sensitive two-dimensional correlated spectroscopy (COSY) for measurements of 1H-1H spin-spin coupling constants in proteins

21 January 2018

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Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions

21 January 2018

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The program XEASY for computer-supported NMR spectral analysis of biological macromolecules

21 January 2018

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Identification of functional domains of the human glutamate transporters EAAT1 and EAAT2.

21 January 2018

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Temperature dependence of human ether-a-go-go-related gene K+ currents.

21 January 2018

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A localized interaction surface for voltage-sensing domains on the pore domain of a K+ channel

21 January 2018

1 reference

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Regional specificity of human ether-a'-go-go-related gene channel activation and inactivation gating

21 January 2018

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VMD: visual molecular dynamics

21 January 2018

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Scalable molecular dynamics with NAMD

21 January 2018

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All-atom empirical potential for molecular modeling and dynamics studies of proteins

21 January 2018

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Extending the treatment of backbone energetics in protein force fields: limitations of gas-phase quantum mechanics in reproducing protein conformational distributions in molecular dynamics simulations

21 January 2018

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Probing the outer mouth structure of the HERG channel with peptide toxin footprinting and molecular modeling.

21 January 2018

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The open pore conformation of potassium channels

21 January 2018

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Identification of protein surfaces by NMR measurements with a pramagnetic Gd(III) chelate

21 January 2018

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Structures of the glycine-rich diastereomeric peptides bombinin H2 and H4.

21 January 2018

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Functional interactions at the interface between voltage-sensing and pore domains in the Shaker K(v) channel.

21 January 2018

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Structural dynamics of an isolated voltage-sensor domain in a lipid bilayer

21 January 2018

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Solid-state NMR spectroscopy applied to a chimeric potassium channel in lipid bilayers.

21 January 2018

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The S4-S5 linker directly couples voltage sensor movement to the activation gate in the human ether-a'-go-go-related gene (hERG) K+ channel.

21 January 2018

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Crystal structure of a mammalian voltage-dependent Shaker family K+ channel

21 January 2018

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Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator.

21 January 2018

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Position of aromatic residues in the S6 domain, not inactivation, dictates cisapride sensitivity of HERG and eag potassium channels

21 January 2018

1 reference

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The HERG K+ channel: progress in understanding the molecular basis of its unusual gating kinetics

21 January 2018

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Drug block of the hERG potassium channel: insight from modeling.

21 January 2018

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Drug binding to the inactivated state is necessary but not sufficient for high-affinity binding to human ether-à-go-go-related gene channels

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M806400200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18996846%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1 reference