(Q46277527)

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WNT/β-catenin signaling promotes VSMCs to osteogenic transdifferentiation and calcification through directly modulating Runx2 gene expression

scientific article published on 16 June 2016

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/27321958

WNT/β-catenin signaling promotes VSMCs to osteogenic transdifferentiation and calcification through directly modulating Runx2 gene expression (English)

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/27321958

author name string

Ting Cai

1

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/27321958

Danqin Sun

2

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PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/27321958

Ying Duan

3

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/27321958

Ping Wen

4

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PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/27321958

Chunsun Dai

5

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21 December 2017

http://europepmc.org/abstract/MED/27321958

Junwei Yang

6

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21 December 2017

http://europepmc.org/abstract/MED/27321958

Weichun He

7

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21 December 2017

http://europepmc.org/abstract/MED/27321958

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16 June 2016

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/27321958

Experimental Cell Research

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PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/27321958

345

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/27321958

2

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PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/27321958

206-217

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/27321958

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MicroRNAs Regulate Vascular Medial Calcification

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Canonical WNT Signaling Promotes Osteogenesis by Directly StimulatingRunx2Gene Expression

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Signaling networks in RUNX2-dependent bone development

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Key Fibrogenic Signaling

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Wnt/beta-catenin signaling: new (and old) players and new insights

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Proximal events in Wnt signal transduction

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Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase

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Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase stabilizes beta-catenin through inhibition of its ubiquitination

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A Rac1/PAK1 cascade controls β-catenin activation in colon cancer cells

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Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes

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7 January 2021

Networks and hubs for the transcriptional control of osteoblastogenesis.

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7 January 2021

High phosphorus diet induces vascular calcification, a related decrease in bone mass and changes in the aortic gene expression

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7 January 2021

Calcification inhibitors and Wnt signaling proteins are implicated in bovine artery smooth muscle cell calcification in the presence of phosphate and vitamin D sterols

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7 January 2021

Vascular calcification in chronic kidney disease is induced by bone morphogenetic protein-2 via a mechanism involving the Wnt/β-catenin pathway.

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7 January 2021

High phosphorus level leads to aortic calcification via β-catenin in chronic kidney disease

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7 January 2021

Magnesium inhibits Wnt/β-catenin activity and reverses the osteogenic transformation of vascular smooth muscle cells

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miR-125b/Ets1 axis regulates transdifferentiation and calcification of vascular smooth muscle cells in a high-phosphate environment

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Plasminogen activator inhibitor-1 is a transcriptional target of the canonical pathway of Wnt/beta-catenin signaling

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The murine gastrin promoter is synergistically activated by transforming growth factor-beta/Smad and Wnt signaling pathways

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Severe hyperparathyroidism with bone abnormalities and metastatic calcification in rats with adenine-induced uraemia.

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Sirtuin 1 retards hyperphosphatemia-induced calcification of vascular smooth muscle cells.

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Wnt/beta-catenin signaling promotes renal interstitial fibrosis

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Sp1 mediates microRNA-29c-regulated type I collagen production in renal tubular epithelial cells

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The many faces and functions of β-catenin

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Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions.

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Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974.

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High-phosphate-induced calcification is related to SM22α promoter methylation in vascular smooth muscle cells.

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Hyperphosphatemia-induced nanocrystals upregulate the expression of bone morphogenetic protein-2 and osteopontin genes in mouse smooth muscle cells in vitro

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Identifiers

10.1016/J.YEXCR.2016.06.007

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/27321958

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/27321958

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