(Q46305320)

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Mutation-, aging-, and gene dosage-dependent accumulation of neuroserpin (G392E) in endoplasmic reticula and lysosomes of neurons in transgenic mice

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18940798

Mutation-, aging-, and gene dosage-dependent accumulation of neuroserpin (G392E) in endoplasmic reticula and lysosomes of neurons in transgenic mice (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18940798

author name string

Akira Takasawa

1

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18940798

Ichiro Kato

2

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18940798

Kumi Takasawa

3

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18940798

Yoko Ishii

4

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18940798

Toshiko Yoshida

5

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18940798

Mohammad H Shehata

6

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18940798

Hiroshi Kawaguchi

7

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18940798

Omar M M Mohafez

8

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18940798

Masakiyo Sasahara

9

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18940798

Koichi Hiraga

10

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18940798

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publication date

21 October 2008

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18940798

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18940798

283

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18940798

51

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18940798

35606-35613

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18940798

Neuroserpin, a brain-associated inhibitor of tissue plasminogen activator is localized primarily in neurons. Implications for the regulation of motor learning and neuronal survival

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

The axonally secreted serine proteinase inhibitor, neuroserpin, inhibits plasminogen activators and plasmin but not thrombin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

Neuroserpin regulates neurite outgrowth in nerve growth factor-treated PC12 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

Impaired explorative behavior and neophobia in genetically modified mice lacking or overexpressing the extracellular serine protease inhibitor neuroserpin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

Familial encephalopathy with neuroserpin inclusion bodies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

Association between conformational mutations in neuroserpin and onset and severity of dementia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

Neuroserpin mutation S52R causes neuroserpin accumulation in neurons and is associated with progressive myoclonus epilepsy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

Mutant Neuroserpin (S49P) that causes familial encephalopathy with neuroserpin inclusion bodies is a poor proteinase inhibitor and readily forms polymers in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

Latent S49P neuroserpin forms polymers in the dementia familial encephalopathy with neuroserpin inclusion bodies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

Neuroserpin Portland (Ser52Arg) is trapped as an inactive intermediate that rapidly forms polymers: implications for the epilepsy seen in the dementia FENIB

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

Crystal structure of neuroserpin: a neuronal serpin involved in a conformational disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

Mutants of neuroserpin that cause dementia accumulate as polymers within the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

Neuroserpin, a neuroprotective factor in focal ischemic stroke.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

Accumulation of mutant neuroserpin precedes development of clinical symptoms in familial encephalopathy with neuroserpin inclusion bodies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

Expression of Thy-1/lacZ fusion genes in the CNS of transgenic mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

Neuroprotective role of transgenic PAF-acetylhydrolase II in mouse models of focal cerebral ischemia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

Subcellular localization of bilirubin in rat brain after in vivo i.v. administration of [3H]bilirubin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

Genetic control of sensitivity to hippocampal cell death induced by kainic acid: a quantitative trait loci analysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

What do dysfunctional serpins tell us about molecular mobility and disease?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

Serpin structure, mechanism, and function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

Serpinopathies and the conformational dementias

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

Neuroserpin (PI-12) is upregulated in high-grade prostate cancer and is associated with survival.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

HuD binds to three AU-rich sequences in the 3'-UTR of neuroserpin mRNA and promotes the accumulation of neuroserpin mRNA and protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

Intracellular accumulation of antithrombin Morioka (C95R), a novel mutation causing type I antithrombin deficiency

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

Autophagy and neurodegeneration: when the cleaning crew goes on strike

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

The intracellular accumulation of polymeric neuroserpin explains the severity of the dementia FENIB.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804125200

21 January 2018

Identifiers

10.1074/JBC.M804125200

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18940798

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https://api.fatcat.wiki/v0/release/gxksm3gkmvhstfd3e3udkl52dy

24 November 2022

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18940798

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