(Q46345796)

English

beta-Catenin is essential for survival of leukemic stem cells insensitive to kinase inhibition in mice with BCR-ABL-induced chronic myeloid leukemia

scientific article published on 25 September 2008

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scholarly article

1 reference

Europe PubMed Central

21 December 2017

http://europepmc.org/abstract/MED/18818703

beta-Catenin is essential for survival of leukemic stem cells insensitive to kinase inhibition in mice with BCR-ABL-induced chronic myeloid leukemia (English)

1 reference

Europe PubMed Central

21 December 2017

http://europepmc.org/abstract/MED/18818703

chronic myeloid leukemia

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1 reference

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author name string

Y Hu

1

1 reference

Europe PubMed Central

21 December 2017

http://europepmc.org/abstract/MED/18818703

Y Chen

2

1 reference

Europe PubMed Central

21 December 2017

http://europepmc.org/abstract/MED/18818703

L Douglas

3

1 reference

Europe PubMed Central

21 December 2017

http://europepmc.org/abstract/MED/18818703

S Li

4

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Europe PubMed Central

21 December 2017

http://europepmc.org/abstract/MED/18818703

language of work or name

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publication date

25 September 2008

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Europe PubMed Central

21 December 2017

http://europepmc.org/abstract/MED/18818703

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Europe PubMed Central

21 December 2017

http://europepmc.org/abstract/MED/18818703

23

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Europe PubMed Central

21 December 2017

http://europepmc.org/abstract/MED/18818703

109-116

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21 December 2017

http://europepmc.org/abstract/MED/18818703

1

1 reference

Europe PubMed Central

21 December 2017

http://europepmc.org/abstract/MED/18818703

https://scigraph.springernature.com/pub.10.1038/leu.2008.262

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Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

1 reference

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7 January 2021

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Frequency of major molecular responses to imatinib or interferon alfa plus cytarabine in newly diagnosed chronic myeloid leukemia

1 reference

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Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia

1 reference

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Molecular monitoring in chronic myeloid leukemia patients who achieve complete cytogenetic remission on imatinib

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Imatinib mesylate-induced molecular remission of Philadelphia chromosome-positive myelodysplastic syndrome.

1 reference

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Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia

1 reference

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7 January 2021

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Establishment of a murine model for therapy-treated chronic myelogenous leukemia using the tyrosine kinase inhibitor STI571.

1 reference

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Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro

1 reference

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The tyrosine kinase inhibitor STI571, like interferon-alpha, preferentially reduces the capacity for amplification of granulocyte-macrophage progenitors from patients with chronic myeloid leukemia

1 reference

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Targeting multiple kinase pathways in leukemic progenitors and stem cells is essential for improved treatment of Ph+ leukemia in mice.

1 reference

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WNT and beta-catenin signalling: diseases and therapies

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Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

1 reference

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Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

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Stabilization of beta-catenin by genetic defects in melanoma cell lines

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Wnt-signalling pathway in ovarian epithelial tumours: increased expression of beta-catenin and GSK3beta

1 reference

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Activation of the Wnt pathway in non small cell lung cancer: evidence of dishevelled overexpression

1 reference

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A role for Wnt signalling in self-renewal of haematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.262

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Wnt proteins are lipid-modified and can act as stem cell growth factors

1 reference

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HIV, but not murine leukemia virus, vectors mediate high efficiency gene transfer into freshly isolated G0/G1 human hematopoietic stem cells

1 reference

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A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.262

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Prospective isolation of human clonogenic common myeloid progenitors

1 reference

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7 January 2021

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BIOLOGY OF HEMATOPOIETIC STEM CELLS AND PROGENITORS: Implications for Clinical Application

1 reference

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7 January 2021

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Hematopoietic stem cells need two signals to prevent apoptosis; BCL-2 can provide one of these, Kitl/c-Kit signaling the other

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.262

7 January 2021

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Hematopoiesis and stem cells: plasticity versus developmental heterogeneity

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.262

7 January 2021

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Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.262

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Bcr-Abl stabilizes beta-catenin in chronic myeloid leukemia through its tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.262

7 January 2021

based on heuristic

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Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML

1 reference

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7 January 2021

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The P190, P210, and P230 forms of the BCR/ABL oncogene induce a similar chronic myeloid leukemia-like syndrome in mice but have different lymphoid leukemogenic activity

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.262

7 January 2021

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The src homology 2 domain of Bcr/Abl is required for efficient induction of chronic myeloid leukemia-like disease in mice but not for lymphoid leukemogenesis or activation of phosphatidylinositol 3-kinase

1 reference

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Tyrosine phosphorylation of Grb2 by Bcr/Abl and epidermal growth factor receptor: a novel regulatory mechanism for tyrosine kinase signaling

1 reference

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Overriding imatinib resistance with a novel ABL kinase inhibitor

1 reference

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Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia

1 reference

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7 January 2021

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inferred from DOI database lookup

Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.262

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/LEU.2008.262

1 reference

Europe PubMed Central

21 December 2017

http://europepmc.org/abstract/MED/18818703

1 reference

Europe PubMed Central

21 December 2017

http://europepmc.org/abstract/MED/18818703

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