(Q46384510)

21 December 2017

title

Ribotoxic stress response to the trichothecene deoxynivalenol in the macrophage involves the SRC family kinase Hck. (English)

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21 December 2017

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Hui-Ren Zhou

1

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21 December 2017

Qunshan Jia

series ordinal

2

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21 December 2017

James J Pestka

series ordinal

3

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21 December 2017

publication date

16 March 2005

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21 December 2017

published in

Toxicological Sciences

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21 December 2017

volume

85

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21 December 2017

issue

2

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21 December 2017

page(s)

916-926

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21 December 2017

Induction of activator protein 1 (AP-1) in macrophages by human immunodeficiency virus type-1 NEF is a cell-type-specific response that requires both hck and MAPK signaling events

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1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Structure and regulation of Src family kinases

21 January 2018

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Verotoxin activates mitogen-activated protein kinase in human peripheral blood monocytes: role in apoptosis and proinflammatory cytokine release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Constitutive activation of the SRC family kinase Hck results in spontaneous pulmonary inflammation and an enhanced innate immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Time- and concentration-dependent production of superoxide anion, nitric oxide, DNA damage and cellular death by ricin in the J774A.1 macrophage cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Other biologic toxin bioweapons: ricin, staphylococcal enterotoxin B, and trichothecene mycotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Mechanical pressure-induced phosphorylation of p38 mitogen-activated protein kinase in epithelial cells via Src and protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Ribotoxic stress response: activation of the stress-activated protein kinase JNK1 by inhibitors of the peptidyl transferase reaction and by sequence-specific RNA damage to the alpha-sarcin/ricin loop in the 28S rRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Modulation of protein translation by Nck-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Oxidant-induced priming of the macrophage involves activation of p38 mitogen-activated protein kinase through an Src-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Gene expression profiling in spleens of deoxynivalenol-exposed mice: immediate early genes as primary targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Downstream targets of urokinase-type plasminogen-activator-mediated signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

The ribotoxic stress response as a potential mechanism for MAP kinase activation in xenobiotic toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Superinduction of IL-2 gene expression by vomitoxin (deoxynivalenol) involves increased mRNA stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Modulation of transcription factor AP-1 activity in murine EL-4 thymoma cells by vomitoxin (deoxynivalenol)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Src-family kinases: rheostats of immune cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Resistance to endotoxic shock and reduced neutrophil migration in mice deficient for the Src-family kinases Hck and Fgr

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

In vitro detection of Shiga toxin using porcine alveolar macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Kinase pathways in chemoattractant-induced degranulation of neutrophils: the role of p38 mitogen-activated protein kinase activated by Src family kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Cyclooxygenase-2 mediates interleukin-6 upregulation by vomitoxin (deoxynivalenol) in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Relationship of Trichothecene Structure to Cox-2 Induction in the Macrophage: Selective Action of Type B (8-Keto) Trichothecenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Effects of vomitoxin (deoxynivalenol) on transcription factor NF-kappa B/Rel binding activity in murine EL-4 thymoma and primary CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Deoxynivalenol-induced IgA production and IgA nephropathy-aberrant mucosal immune response with systemic repercussions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Deoxynivalenol: toxicology and potential effects on humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Cellular and molecular mechanisms for immune modulation by deoxynivalenol and other trichothecenes: unraveling a paradox

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

The interplay between Src and integrins in normal and tumor biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Development of early apoptosis and changes in T-cell subsets in mouse thymocyte primary cultures treated with nivalenol

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Synthetic anisomycin analogues activating the JNK/SAPK1 and p38/SAPK2 pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Macrophage signalling upon mycobacterial infection: the MAP kinases lead the way.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Physical and functional interaction between Hck tyrosine kinase and guanine nucleotide exchange factor C3G results in apoptosis, which is independent of C3G catalytic domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Differential upregulation of TNF-alpha, IL-6, and IL-8 production by deoxynivalenol (vomitoxin) and other 8-ketotrichothecenes in a human macrophage model

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Cellular functions regulated by Src family kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Basic mechanisms of transcript elongation and its regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Potentiation of trichothecene-induced leukocyte cytotoxicity and apoptosis by TNF-α and Fas activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Comparative susceptibility of B cells with different lineages to cytotoxicity and apoptosis induction by translational inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Mechanism of activation of the double-stranded-RNA-dependent protein kinase, PKR: role of dimerization and cellular localization in the stimulation of PKR phosphorylation of eukaryotic initiation factor-2 (eIF2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Superinduction of TNF-alpha and IL-6 in macrophages by vomitoxin (deoxynivalenol) modulated by mRNA stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Effects of vomitoxin (deoxynivalenol) on the binding of transcription factors AP-1, NF-kappaB, and NF-IL6 in raw 264.7 macrophage cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Identification and requirement of three ribosome binding domains in dsRNA-dependent protein kinase (PKR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Vomitoxin (deoxynivalenol)-mediated inhibition of nuclear protein binding to NRE-A, an IL-2 promoter negative regulatory element, in EL-4 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

An essential role for the interferon-inducible, double-stranded RNA-activated protein kinase PKR in the tumor necrosis factor-induced apoptosis in U937 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

Differential cytokine mRNA expression in mice after oral exposure to the trichothecene vomitoxin (deoxynivalenol): dose response and time course

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI146

21 January 2018

Identifiers

DOI

10.1093/TOXSCI/KFI146

1 reference

21 December 2017

1 reference

21 December 2017