(Q46408835)

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Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle.

scientific article published on 27 February 2017

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4 April 2020

Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle (English)

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4 April 2020

reactive oxygen species

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4 April 2020

Akihiro Kikuchi

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4 April 2020

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Hirofumi Misu

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4 April 2020

Hiroaki Takayama

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4 April 2020

Yuichiro Mita

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4 April 2020

Kiyo-Aki Ishii

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4 April 2020

Keita Chikamoto

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4 April 2020

Takehiro Kanamori

8

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4 April 2020

Natsumi Tajima

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4 April 2020

Fei Lan

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4 April 2020

Yumie Takeshita

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4 April 2020

Masao Honda

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4 April 2020

Mutsumi Tanaka

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4 April 2020

Seiji Kato

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4 April 2020

Naoto Matsuyama

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4 April 2020

Yuya Yoshioka

16

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4 April 2020

Kaito Iwayama

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4 April 2020

Kumpei Tokuyama

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4 April 2020

Nobuhiko Akazawa

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4 April 2020

Seiji Maeda

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4 April 2020

Kazuhiro Takekoshi

21

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4 April 2020

Seiichi Matsugo

22

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4 April 2020

Noriko Noguchi

23

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4 April 2020

Shuichi Kaneko

24

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4 April 2020

Toshinari Takamura

25

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27 February 2017

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4 April 2020

Nature Medicine

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4 April 2020

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4 April 2020

508-516

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4 April 2020

https://scigraph.springernature.com/pub.10.1038/nm.4295

0 references

Mechanisms governing the health and performance benefits of exercise

1 reference

https://api.crossref.org/works/10.1038%2FNM.4295

7 January 2021

based on heuristic

inferred from DOI database lookup

Familial aggregation of VO(2max) response to exercise training: results from the HERITAGE Family Study

1 reference

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7 January 2021

based on heuristic

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Resistance to the beneficial effects of exercise in type 2 diabetes: are some individuals programmed to fail?

1 reference

https://api.crossref.org/works/10.1038%2FNM.4295

7 January 2021

based on heuristic

inferred from DOI database lookup

A liver-derived secretory protein, selenoprotein P, causes insulin resistance.

1 reference

https://api.crossref.org/works/10.1038%2FNM.4295

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of selenoprotein P as a selenium supply protein

1 reference

https://api.crossref.org/works/10.1038%2FNM.4295

7 January 2021

based on heuristic

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Selenoprotein P-expression, functions, and roles in mammals

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7 January 2021

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LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies

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7 January 2021

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AMPK and PPARdelta agonists are exercise mimetics

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7 January 2021

based on heuristic

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The role of exercise and PGC1alpha in inflammation and chronic disease

1 reference

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7 January 2021

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Response and adaptation of skeletal muscle to exercise--the role of reactive oxygen species

1 reference

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7 January 2021

based on heuristic

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Redox implications of AMPK-mediated signal transduction beyond energetic clues

1 reference

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7 January 2021

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Exercise activation of muscle peroxisome proliferator-activated receptor-gamma coactivator-1alpha signaling is redox sensitive

1 reference

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7 January 2021

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Antioxidants prevent health-promoting effects of physical exercise in humans

1 reference

https://api.crossref.org/works/10.1038%2FNM.4295

7 January 2021

based on heuristic

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Oral administration of vitamin C decreases muscle mitochondrial biogenesis and hampers training-induced adaptations in endurance performance.

1 reference

https://api.crossref.org/works/10.1038%2FNM.4295

7 January 2021

based on heuristic

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Production of selenoprotein P (Sepp1) by hepatocytes is central to selenium homeostasis

1 reference

https://api.crossref.org/works/10.1038%2FNM.4295

7 January 2021

based on heuristic

inferred from DOI database lookup

Serum selenoprotein P levels in patients with type 2 diabetes and prediabetes: implications for insulin resistance, inflammation, and atherosclerosis

1 reference

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7 January 2021

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Apolipoprotein E receptor-2 (ApoER2) mediates selenium uptake from selenoprotein P by the mouse testis

1 reference

https://api.crossref.org/works/10.1038%2FNM.4295

7 January 2021

based on heuristic

inferred from DOI database lookup

Megalin mediates selenoprotein P uptake by kidney proximal tubule epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FNM.4295

7 January 2021

based on heuristic

inferred from DOI database lookup

Exercise metabolism and the molecular regulation of skeletal muscle adaptation

1 reference

https://api.crossref.org/works/10.1038%2FNM.4295

7 January 2021

based on heuristic

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Changes in gene expression in responders and nonresponders to a low-intensity walking intervention.

1 reference

https://api.crossref.org/works/10.1038%2FNM.4295

7 January 2021

based on heuristic

inferred from DOI database lookup

Insulin-resistant muscle is exercise resistant: evidence for reduced response of nuclear-encoded mitochondrial genes to exercise

1 reference

https://api.crossref.org/works/10.1038%2FNM.4295

7 January 2021

based on heuristic

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Short-term exercise training does not stimulate skeletal muscle ATP synthesis in relatives of humans with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FNM.4295

7 January 2021

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Acute exercise remodels promoter methylation in human skeletal muscle.

1 reference

https://api.crossref.org/works/10.1038%2FNM.4295

7 January 2021

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The role of diet and exercise in the transgenerational epigenetic landscape of T2DM.

1 reference

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7 January 2021

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Serum selenium and selenoprotein P status in adult Danes - 8-year followup

1 reference

https://api.crossref.org/works/10.1038%2FNM.4295

7 January 2021

based on heuristic

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Selenoprotein W serves as an antioxidant in chicken myoblasts

1 reference

https://api.crossref.org/works/10.1038%2FNM.4295

7 January 2021

based on heuristic

inferred from DOI database lookup

Selenoprotein W enhances skeletal muscle differentiation by inhibiting TAZ binding to 14-3-3 protein

1 reference

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7 January 2021

based on heuristic

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Long isoform mouse selenoprotein P (Sepp1) supplies rat myoblast L8 cells with selenium via endocytosis mediated by heparin binding properties and apolipoprotein E receptor-2 (ApoER2)

1 reference

https://api.crossref.org/works/10.1038%2FNM.4295

7 January 2021

based on heuristic

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Selenoprotein P and apolipoprotein E receptor-2 interact at the blood-brain barrier and also within the brain to maintain an essential selenium pool that protects against neurodegeneration

1 reference

https://api.crossref.org/works/10.1038%2FNM.4295

7 January 2021

based on heuristic

inferred from DOI database lookup

Neurological dysfunction occurs in mice with targeted deletion of the selenoprotein P gene

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Neurodegeneration in mice resulting from loss of functional selenoprotein P or its receptor apolipoprotein E receptor 2.

1 reference

https://api.crossref.org/works/10.1038%2FNM.4295

7 January 2021

based on heuristic

inferred from DOI database lookup

Deletion of selenoprotein P alters distribution of selenium in the mouse

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Progression of neurodegeneration and morphologic changes in the brains of juvenile mice with selenoprotein P deleted

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7 January 2021

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Exercise Promotes Healthy Aging of Skeletal Muscle

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7 January 2021

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American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise

1 reference

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7 January 2021

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7 January 2021

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Mitohormesis: Promoting Health and Lifespan by Increased Levels of Reactive Oxygen Species (ROS).

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7 January 2021

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1 reference

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7 January 2021

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The unfolded protein response mediates adaptation to exercise in skeletal muscle through a PGC-1α/ATF6α complex

1 reference

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LECT2 functions as a hepatokine that links obesity to skeletal muscle insulin resistance.

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1 reference

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Impact of resistance exercise during bed rest on skeletal muscle sarcopenia and myosin isoform distribution

1 reference

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7 January 2021

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Selenoprotein P in human plasma as an extracellular phospholipid hydroperoxide glutathione peroxidase. Isolation and enzymatic characterization of human selenoprotein p

1 reference

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7 January 2021

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inferred from DOI database lookup

Effect of selenium on selenoprotein P expression in cultured liver cells

1 reference

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7 January 2021

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7 January 2021

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1 reference

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1 reference

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7 January 2021

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Development of a Sol Particle Homogeneous Immunoassay for Measuring Full-Length Selenoprotein P in Human Serum.

1 reference

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7 January 2021

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BoxPlotR: a web tool for generation of box plots

1 reference

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7 January 2021

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10.1038/NM.4295

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28263310%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28263310%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

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