(Q46421308)

English

High-throughput microplate phosphorylation assays based on DevR-DevS/Rv2027c 2-component signal transduction pathway to screen for novel antitubercular compounds

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scholarly article

1 reference

22 December 2017

http://europepmc.org/abstract/MED/15809317

High-throughput microplate phosphorylation assays based on DevR-DevS/Rv2027c 2-component signal transduction pathway to screen for novel antitubercular compounds (English)

1 reference

22 December 2017

http://europepmc.org/abstract/MED/15809317

phosphorylation

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author name string

Deepak Kumar Saini

1

1 reference

22 December 2017

http://europepmc.org/abstract/MED/15809317

Jaya Sivaswami Tyagi

2

1 reference

22 December 2017

http://europepmc.org/abstract/MED/15809317

publication date

1 April 2005

1 reference

22 December 2017

http://europepmc.org/abstract/MED/15809317

Journal of Biomolecular Screening

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22 December 2017

http://europepmc.org/abstract/MED/15809317

10

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22 December 2017

http://europepmc.org/abstract/MED/15809317

215-224

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22 December 2017

http://europepmc.org/abstract/MED/15809317

3

1 reference

22 December 2017

http://europepmc.org/abstract/MED/15809317

Mechanisms of latency in Mycobacterium tuberculosis

1 reference

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The mystery of the mycobacterial 'persistor'

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The clinical spectrum of primary tuberculosis in adults. Confusion with reinfection in the pathogenesis of chronic tuberculosis

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Inhibitors of bacterial two-component signalling systems

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Communication modules in bacterial signaling proteins

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The pleiotropic two-component regulatory system PhoP-PhoQ

1 reference

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DevR-DevS is a bona fide two-component system of Mycobacterium tuberculosis that is hypoxia-responsive in the absence of the DNA-binding domain of DevR.

1 reference

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Cross talk between DevS sensor kinase homologue, Rv2027c, and DevR response regulator of Mycobacterium tuberculosis

1 reference

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Two sensor kinases contribute to the hypoxic response of Mycobacterium tuberculosis

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Mycobacterium bovis BCG response regulator essential for hypoxic dormancy

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Rv3133c/dosR is a transcription factor that mediates the hypoxic response of Mycobacterium tuberculosis

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Inhibition of respiration by nitric oxide induces a Mycobacterium tuberculosis dormancy program

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Disruption of response regulator gene, devR, leads to attenuation in virulence of Mycobacterium tuberculosis.

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21 January 2018

Deletion of two-component regulatory systems increases the virulence of Mycobacterium tuberculosis

1 reference

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A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

1 reference

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Cloning, overexpression, purification, and matrix-assisted refolding of DevS (Rv 3132c) histidine protein kinase of Mycobacterium tuberculosis

1 reference

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Analysis of two-component signal transduction systems involved in transcriptional regulation

1 reference

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Two-component signal transduction

1 reference

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Synthesis and preliminary evaluation of benzimidazole derivatives as antimicrobial agents.

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New benzimidazole derivatives as antimycobacterial agents.

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Homidium bromide as a chemoprophylactic for cattle trypanosomiasis in Kenya

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Histidine kinases as targets for new antimicrobial agents

1 reference

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21 January 2018

Use of combinatorial library screening to identify inhibitors of a bacterial two-component signal transduction kinase

1 reference

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21 January 2018

The mechanism of action of inhibitors of bacterial two-component signal transduction systems

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Development of a Screening Assay to Measure the Loss of Antibacterial Activity in the Presence of Proteins: Its Use in Optimizing Compound Structure

1 reference

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A specific mechanism of nonspecific inhibition

1 reference

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Identification and Prediction of Promiscuous Aggregating Inhibitors among Known Drugs

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Inhibitors of two-component signal transduction systems: inhibition of alginate gene activation in Pseudomonas aeruginosa

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An essential role for phoP in Mycobacterium tuberculosis virulence

1 reference

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Transient requirement of the PrrA-PrrB two-component system for early intracellular multiplication of Mycobacterium tuberculosis

1 reference

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21 January 2018

A two-component signal transduction system with a PAS domain-containing sensor is required for virulence of Mycobacterium tuberculosis in mice

1 reference

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Mycobacterium tuberculosis signal transduction system required for persistent infections

1 reference

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21 January 2018

Identifiers

10.1177/1087057104272090

1 reference

22 December 2017

http://europepmc.org/abstract/MED/15809317

1 reference

22 December 2017

http://europepmc.org/abstract/MED/15809317

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