(Q46426188)

22 December 2017

title

CBFbeta-SMMHC slows proliferation of primary murine and human myeloid progenitors (English)

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22 December 2017

author name string

D'Costa J

1

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22 December 2017

Chaudhuri S

2

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22 December 2017

Civin CI

3

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22 December 2017

Friedman AD

4

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22 December 2017

publication date

1 June 2005

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22 December 2017

published in

Leukemia

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22 December 2017

volume

19

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22 December 2017

issue

6

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22 December 2017

page(s)

921-929

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22 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.leu.2403755

exact match

0 references

cites work

Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia

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Molecular cloning and characterization of PEBP2 beta, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2 alpha

21 January 2018

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Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor

21 January 2018

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Acute Myeloid Leukemia with Inv(16) Produces a Chimeric Transcription Factor with a Myosin Heavy Chain Tail

21 January 2018

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The leukemic protein core binding factor beta (CBFbeta)-smooth-muscle myosin heavy chain sequesters CBFalpha2 into cytoskeletal filaments and aggregates

21 January 2018

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The inv(16) fusion protein associates with corepressors via a smooth muscle myosin heavy-chain domain

21 January 2018

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A 29 residue region of the sarcomeric myosin rod is necessary for filament formation.

21 January 2018

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Multimerization via its myosin domain facilitates nuclear localization and inhibition of core binding factor (CBF) activities by the CBFbeta-smooth muscle myosin heavy chain myeloid leukemia oncoprotein

21 January 2018

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Runx1 is expressed in adult mouse hematopoietic stem cells and differentiating myeloid and lymphoid cells, but not in maturing erythroid cells

21 January 2018

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Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges

21 January 2018

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Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells

21 January 2018

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Exogenous cdk4 overcomes reduced cdk4 RNA and inhibition of G1 progression in hematopoietic cells expressing a dominant-negative CBF - a model for overcoming inhibition of proliferation by CBF oncoproteins

21 January 2018

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Limited overlapping roles of P15(INK4b) and P18(INK4c) cell cycle inhibitors in proliferation and tumorigenesis

21 January 2018

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CCAAT/enhancer-binding proteins are required for granulopoiesis independent of their induction of the granulocyte colony-stimulating factor receptor

21 January 2018

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AML1/RUNX1 increases during G1 to S cell cycle progression independent of cytokine-dependent phosphorylation and induces cyclin D3 gene expression

21 January 2018

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Mouse development and cell proliferation in the absence of D-cyclins.

21 January 2018

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c-Myc overcomes cell cycle inhibition by CBFbeta-SMMHC, a myeloid leukemia oncoprotein

21 January 2018

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Altered affinity of CBF beta-SMMHC for Runx1 explains its role in leukemogenesis

21 January 2018

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Molecular basis for a dominant inactivation of RUNX1/AML1 by the leukemogenic inversion 16 chimera

21 January 2018

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CBF beta-SMMHC, expressed in M4Eo AML, reduced CBF DNA-binding and inhibited the G1 to S cell cycle transition at the restriction point in myeloid and lymphoid cells

21 January 2018

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7 January 2021

The core binding factor (CBF) alpha interaction domain and the smooth muscle myosin heavy chain (SMMHC) segment of CBFbeta-SMMHC are both required to slow cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403755

7 January 2021

Haploinsufficiency of AML1 results in a decrease in the number of LTR-HSCs while simultaneously inducing an increase in more mature progenitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403755

7 January 2021

The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403755

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2403755

1 reference

22 December 2017

1 reference

22 December 2017