(Q46434108)

22 December 2017

title

Kinase switching in mesenchymal-like non-small cell lung cancer lines contributes to EGFR inhibitor resistance through pathway redundancy (English)

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22 December 2017

non-small-cell lung carcinoma

main subject

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Stuart Thomson

1

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22 December 2017

Filippo Petti

2

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22 December 2017

Izabela Sujka-Kwok

3

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22 December 2017

David Epstein

4

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22 December 2017

John D Haley

5

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22 December 2017

publication date

12 August 2008

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22 December 2017

Clinical & Experimental Metastasis

published in

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22 December 2017

volume

25

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22 December 2017

issue

8

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22 December 2017

page(s)

843-854

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22 December 2017

https://scigraph.springernature.com/pub.10.1007/s10585-008-9200-4

exact match

0 references

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12 December 2020

Loss of homotypic cell adhesion by epithelial-mesenchymal transition or mutation limits sensitivity to epidermal growth factor receptor inhibition

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12 December 2020

Molecular correlates of gefitinib responsiveness in human bladder cancer cells

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12 December 2020

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12 December 2020

Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines.

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12 December 2020

Temporal quantitation of mutant Kit tyrosine kinase signaling attenuated by a novel thiophene kinase inhibitor OSI-930.

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Tyrosine phosphorylation of p145met mediated by EGFR and Src is required for serum-independent survival of human bladder carcinoma cells

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12 December 2020

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12 December 2020

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Epithelial versus mesenchymal phenotype determines in vitro sensitivity and predicts clinical activity of erlotinib in lung cancer patients

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Induction by transforming growth factor-beta1 of epithelial to mesenchymal transition is a rare event in vitro

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12 December 2020

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12 December 2020

MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

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12 December 2020

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12 December 2020

Inactivation of Akt by the epidermal growth factor receptor inhibitor erlotinib is mediated by HER-3 in pancreatic and colorectal tumor cell lines and contributes to erlotinib sensitivity

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12 December 2020

TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells

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12 December 2020

Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition

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12 December 2020

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12 December 2020

Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail

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12 December 2020

Autocrine PDGFR signaling promotes mammary cancer metastasis

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12 December 2020

OSI-930: a novel selective inhibitor of Kit and kinase insert domain receptor tyrosine kinases with antitumor activity in mouse xenograft models

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12 December 2020

Snail blocks the cell cycle and confers resistance to cell death

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12 December 2020

The transcriptional repressor Snail promotes mammary tumor recurrence

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12 December 2020

Epithelial-mesenchymal transitions in tumour progression

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12 December 2020

Signal pathway profiling of epithelial and stromal compartments of colonic carcinoma reveals epithelial-mesenchymal transition

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12 December 2020

Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas

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12 December 2020

10.1007/S10585-008-9200-4

Identifiers

DOI

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22 December 2017

PubMed ID

18696232

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22 December 2017