(Q46449699)

22 December 2017

title

Life extension through neurofibromin mitochondrial regulation and antioxidant therapy for neurofibromatosis-1 in Drosophila melanogaster (English)

1 reference

22 December 2017

main subject

Drosophila melanogaster

0 references

Rutabaga Dmel_CG9533

1 reference

GOA release 2020-03-11

author name string

James Jiayuan Tong

1

1 reference

22 December 2017

Samuel E Schriner

2

1 reference

22 December 2017

David McCleary

3

1 reference

22 December 2017

Brian J Day

4

1 reference

22 December 2017

Douglas C Wallace

5

1 reference

22 December 2017

language of work or name

English

0 references

publication date

18 March 2007

1 reference

22 December 2017

published in

Nature Genetics

1 reference

22 December 2017

volume

39

1 reference

22 December 2017

issue

4

1 reference

22 December 2017

page(s)

476-485

1 reference

22 December 2017

Ras/Raf/ERK signalling and NF1.

cites work

1 reference

Pleiotropy, Natural Selection, and the Evolution of Senescence

21 January 2018

1 reference

Malignancy in neurofibromatosis type 1.

21 January 2018

1 reference

7 January 2021

Recent advances in neurofibromatosis type 1.

1 reference

7 January 2021

A circadian output in Drosophila mediated by neurofibromatosis-1 and Ras/MAPK.

1 reference

7 January 2021

A neurofibromatosis-1-regulated pathway is required for learning in Drosophila

1 reference

7 January 2021

Neurofibromin regulates G protein-stimulated adenylyl cyclase activity

1 reference

7 January 2021

Rescue of a Drosophila NF1 mutant phenotype by protein kinase A.

1 reference

7 January 2021

The genetic and molecular pathogenesis of NF1 and NF2.

1 reference

7 January 2021

Requirement of Drosophila NF1 for activation of adenylyl cyclase by PACAP38-like neuropeptides

1 reference

7 January 2021

Synaptic plasticity in Drosophila memory and hyperexcitable mutants: role of cAMP cascade

1 reference

7 January 2021

Paraquat: model for oxidant-initiated toxicity

1 reference

7 January 2021

A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

1 reference

7 January 2021

Oxidative damage during aging targets mitochondrial aconitase

1 reference

7 January 2021

Flavin-dependent antioxidant properties of a new series of meso-N,N'-dialkyl-imidazolium substituted manganese(III) porphyrins

1 reference

7 January 2021

Metalloporphyrin class of therapeutic catalytic antioxidants

1 reference

7 January 2021

Catalytic antioxidants: a radical approach to new therapeutics

1 reference

7 January 2021

Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons

1 reference

7 January 2021

Targeted neuronal gene expression and longevity in Drosophila.

1 reference

7 January 2021

PLEIOTROPY, NATURAL SELECTION, AND THE EVOLUTION OF SENESCENCE

1 reference

7 January 2021

Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster.

1 reference

7 January 2021

Effects of simultaneous over-expression of Cu/ZnSOD and MnSOD on Drosophila melanogaster life span

1 reference

7 January 2021

The effects of exogenous antioxidants on lifespan and oxidative stress resistance in Drosophila melanogaster

1 reference

7 January 2021

Dependence of excitotoxic neurodegeneration on mitochondrial aconitase inactivation

1 reference

7 January 2021

Mitochondrial oxidative stress in human hepatoma cells exposed to stavudine

1 reference

7 January 2021

Regulation of PGC-1 promoter activity by protein kinase B and the forkhead transcription factor FKHR.

1 reference

7 January 2021

High-resolution dynamics of the transcriptional response to nutrition in Drosophila: a key role for dFOXO.

1 reference

7 January 2021

Cyclic adenosine monophosphate-dependent phosphorylation of mammalian mitochondrial proteins: enzyme and substrate characterization and functional role.

1 reference

7 January 2021

The phosphorylation of subunits of complex I from bovine heart mitochondria.

1 reference

7 January 2021

Phosphorylation of B14.5a Subunit from Bovine Heart Complex I Identified by Titanium Dioxide Selective Enrichment and Shotgun Proteomics

1 reference

7 January 2021

Regulation by the cAMP cascade of oxygen free radical balance in mammalian cells.

1 reference

7 January 2021

Complex I and the cAMP cascade in human physiopathology.

1 reference

7 January 2021

cAMP controls oxygen metabolism in mammalian cells

1 reference

7 January 2021

mtDNA mutations increase tumorigenicity in prostate cancer

1 reference

7 January 2021

Mitochondrial mutations in cancer

1 reference

7 January 2021

Superoxide and hydrogen peroxide in relation to mammalian cell proliferation

1 reference

7 January 2021

In vivo and in organello assessment of OXPHOS activities

1 reference

7 January 2021

Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice

1 reference

7 January 2021

Superoxide dismutase: improved assays and an assay applicable to acrylamide gels

1 reference

7 January 2021

Identifiers

DOI

10.1038/NG2004

1 reference

22 December 2017

1 reference

22 December 2017