(Q46473313)

English

Phosphodiesterase-5 inhibition abolishes neuron apoptosis induced by chronic hypoxia independently of hypoxia-inducible factor-1alpha signaling

scientific article published on 18 July 2008

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scholarly article

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18641057

Phosphodiesterase-5 inhibition abolishes neuron apoptosis induced by chronic hypoxia independently of hypoxia-inducible factor-1alpha signaling (English)

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18641057

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22 December 2017

http://europepmc.org/abstract/MED/18641057

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22 December 2017

http://europepmc.org/abstract/MED/18641057

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22 December 2017

http://europepmc.org/abstract/MED/18641057

author name string

Paola Bianciardi

2

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18641057

Raffaella Ronchi

3

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18641057

Monica Fantacci

4

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18641057

publication date

18 July 2008

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Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18641057

Experimental Biology and Medicine

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Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18641057

233

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1222-1230

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22 December 2017

http://europepmc.org/abstract/MED/18641057

Recent advances in insulin gene therapy for type 1 diabetes.

1 reference

https://api.crossref.org/works/10.3181%2F0802-RM-73

21 January 2018

Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1.

1 reference

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21 January 2018

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

https://api.crossref.org/works/10.3181%2F0802-RM-73

21 January 2018

Chronic in vivo hypoxia in various organs: hypoxia-inducible factor-1alpha and apoptosis.

1 reference

https://api.crossref.org/works/10.3181%2F0802-RM-73

21 January 2018

Carbamylated erythropoietin ameliorates the metabolic stress induced in vivo by severe chronic hypoxia

1 reference

https://api.crossref.org/works/10.3181%2F0802-RM-73

21 January 2018

Phosphodiesterase type 5 as a target for the treatment of hypoxia-induced pulmonary hypertension

1 reference

https://api.crossref.org/works/10.3181%2F0802-RM-73

21 January 2018

The effect of vardenafil, a potent and highly selective phosphodiesterase-5 inhibitor for the treatment of erectile dysfunction, on the cardiovascular response to exercise in patients with coronary artery disease.

1 reference

https://api.crossref.org/works/10.3181%2F0802-RM-73

21 January 2018

Sildenafil induces delayed preconditioning through inducible nitric oxide synthase-dependent pathway in mouse heart.

1 reference

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21 January 2018

Sildenafil increased exercise capacity during hypoxia at low altitudes and at Mount Everest base camp: a randomized, double-blind, placebo-controlled crossover trial

1 reference

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21 January 2018

Phosphodiesterase type 5 and high altitude pulmonary hypertension.

1 reference

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21 January 2018

Sildenafil inhibits altitude-induced hypoxemia and pulmonary hypertension.

1 reference

https://api.crossref.org/works/10.3181%2F0802-RM-73

21 January 2018

Sildenafil improves cardiac output and exercise performance during acute hypoxia, but not normoxia.

1 reference

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21 January 2018

Long-term use of sildenafil in the therapeutic management of heart failure

1 reference

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21 January 2018

Phosphodiesterase-5 inhibition with sildenafil attenuates cardiomyocyte apoptosis and left ventricular dysfunction in a chronic model of doxorubicin cardiotoxicity

1 reference

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21 January 2018

Phosphodiesterase-5 inhibitor sildenafil preconditions adult cardiac myocytes against necrosis and apoptosis. Essential role of nitric oxide signaling.

1 reference

https://api.crossref.org/works/10.3181%2F0802-RM-73

21 January 2018

Functional recovery in aged and young rats after embolic stroke: treatment with a phosphodiesterase type 5 inhibitor

1 reference

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21 January 2018

Delayed treatment with sildenafil enhances neurogenesis and improves functional recovery in aged rats after focal cerebral ischemia

1 reference

https://api.crossref.org/works/10.3181%2F0802-RM-73

21 January 2018

Chronic hypoxia: a model for cyanotic congenital heart defects

1 reference

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21 January 2018

Pharmacological preconditioning with sildenafil: Basic mechanisms and clinical implications

1 reference

https://api.crossref.org/works/10.3181%2F0802-RM-73

21 January 2018

Mechanism and potential of the growth-inhibitory actions of vitamin D and ana-logs.

1 reference

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21 January 2018

Phosphodiesterase inhibitors are neuroprotective to cultured spinal motor neurons

1 reference

https://api.crossref.org/works/10.3181%2F0802-RM-73

21 January 2018

NO generation from nitrite and its role in vascular control

1 reference

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21 January 2018

Role of hypoxia inducible factor-1 alpha in modulation of apoptosis resistance

1 reference

https://api.crossref.org/works/10.3181%2F0802-RM-73

21 January 2018

Hypoxia-induced ischemic tolerance in neonatal rat brain involves enhanced ERK1/2 signaling

1 reference

https://api.crossref.org/works/10.3181%2F0802-RM-73

21 January 2018

A hypoxia-driven vascular endothelial growth factor/Flt1 autocrine loop interacts with hypoxia-inducible factor-1alpha through mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2 pathway in neuroblastoma

1 reference

https://api.crossref.org/works/10.3181%2F0802-RM-73

21 January 2018

The selective A2A receptor antagonist SCH 58261 protects from neurological deficit, brain damage and activation of p38 MAPK in rat focal cerebral ischemia.

1 reference

https://api.crossref.org/works/10.3181%2F0802-RM-73

21 January 2018

Hypoxic induction of endoglin via mitogen-activated protein kinases in mouse brain microvascular endothelial cells

1 reference

https://api.crossref.org/works/10.3181%2F0802-RM-73

21 January 2018

p38 Mitogen-activated protein kinase mediates hypoxic regulation of Mdm2 and p53 in neurons

1 reference

https://api.crossref.org/works/10.3181%2F0802-RM-73

21 January 2018

Antiproliferative effect of sildenafil on human pulmonary artery smooth muscle cells

1 reference

https://api.crossref.org/works/10.3181%2F0802-RM-73

21 January 2018

Activation of p38 has opposing effects on the proliferation and migration of endothelial cells

1 reference

https://api.crossref.org/works/10.3181%2F0802-RM-73

21 January 2018

A death-promoting role for extracellular signal-regulated kinase

1 reference

https://api.crossref.org/works/10.3181%2F0802-RM-73

21 January 2018

JNK- and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells

1 reference

https://api.crossref.org/works/10.3181%2F0802-RM-73

21 January 2018

cGMP-dependent protein kinase type I inhibits TAB1-p38 mitogen-activated protein kinase apoptosis signaling in cardiac myocytes

1 reference

https://api.crossref.org/works/10.3181%2F0802-RM-73

21 January 2018

Bcl-2 Phosphorylation by p38 MAPK

1 reference

https://api.crossref.org/works/10.3181%2F0802-RM-73

21 January 2018

Identifiers

10.3181/0802-RM-73

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18641057

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18641057

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