(Q46483879)

22 December 2017

title

A chimeric human-cat fusion protein blocks cat-induced allergy (English)

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22 December 2017

author name string

Daocheng Zhu

1

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22 December 2017

Christopher L Kepley

2

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22 December 2017

Ke Zhang

3

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22 December 2017

Tetsuya Terada

4

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22 December 2017

Takechiyo Yamada

5

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22 December 2017

Andrew Saxon

6

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22 December 2017

language of work or name

English

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publication date

27 March 2005

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22 December 2017

published in

Nature Medicine

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22 December 2017

volume

11

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22 December 2017

issue

4

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22 December 2017

page(s)

446-449

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22 December 2017

https://scigraph.springernature.com/pub.10.1038/nm1219

exact match

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cites work

Effect of anti-IgE therapy in patients with peanut allergy

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Immunologically mediated signaling in basophils and mast cells: finding therapeutic targets for allergic diseases in the human FcvarepsilonR1 signaling pathway.

21 January 2018

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Activating and inhibitory signaling in mast cells: new opportunities for therapeutic intervention?

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Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB.

21 January 2018

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A novel human immunoglobulin Fc gamma Fc epsilon bifunctional fusion protein inhibits Fc epsilon RI-mediated degranulation

21 January 2018

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A bispecific antibody against human IgE and human FcgammaRII that inhibits antigen-induced histamine release by human mast cells and basophils

21 January 2018

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Co-aggregation of FcgammaRII with FcepsilonRI on human mast cells inhibits antigen-induced secretion and involves SHIP-Grb2-Dok complexes

21 January 2018

1 reference

High-level expression of immunoreactive recombinant cat allergen (Fel d 1): Targeting to antigen-presenting cells.

21 January 2018

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Human HMC-1 mast cells exclusively express the Fc gamma RII subtype of IgG receptor

21 January 2018

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Multiple defects in Fc epsilon RI signaling in Syk-deficient nonreleaser basophils and IL-3-induced recovery of Syk expression and secretion.

21 January 2018

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Transgenic mice expressing the human high-affinity immunoglobulin (Ig) E receptor alpha chain respond to human IgE in mast cell degranulation and in allergic reactions

21 January 2018

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Inhibition of allergen-specific IgE reactivity by a human Ig Fcgamma-Fcepsilon bifunctional fusion protein.

21 January 2018

1 reference

Abolition of anaphylaxis by targeted disruption of the high affinity immunoglobulin E receptor alpha chain gene

21 January 2018

1 reference

Sensitisation, asthma, and a modified Th2 response in children exposed to cat allergen: a population-based cross-sectional study

21 January 2018

1 reference

The same tyrosine-based inhibition motif, in the intra-cytoplasmic domain of FcγRIIB, regulates negatively BCR-, TCR-, and FcR-dependent cell activation

21 January 2018

1 reference

Selective in vivo recruitment of the phosphatidylinositol phosphatase SHIP by phosphorylated FcγRIIB during negative regulation of IgE-dependent mouse mast cell activation

21 January 2018

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Negative regulation of FcϵRI signaling by FcγRII costimulation in human blood basophils

21 January 2018

1 reference

7 January 2021

Regulation of high-affinity IgE receptor-mediated mast cell activation by murine low-affinity IgG receptors.

1 reference

7 January 2021

Amino acid sequence of Fel dI, the major allergen of the domestic cat: protein sequence analysis and cDNA cloning.

1 reference

7 January 2021

Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli

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7 January 2021

Fel d 1-specific IgG antibodies induced by natural exposure have blocking activity in skin tests

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7 January 2021

A computer-controlled research ventilator for small animals: design and evaluation

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7 January 2021

Identifiers

DOI

10.1038/NM1219

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22 December 2017

Dimensions Publication ID

1012685637

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22 December 2017