(Q46485002)

22 December 2017

title

Induction of neurite outgrowth by interleukin-6 is accompanied by activation of Stat3 signaling pathway in a variant PC12 cell (E2) line (English)

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22 December 2017

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Wu YY

1

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22 December 2017

Bradshaw RA

series ordinal

2

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22 December 2017

language of work or name

English

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publication date

1 May 1996

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22 December 2017

Journal of Biological Chemistry

published in

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22 December 2017

volume

271

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22 December 2017

page(s)

13023-13032

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22 December 2017

issue

22

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22 December 2017

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

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New insights into protein-tyrosine kinase receptor signaling complexes

21 January 2018

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Molecular cloning of the mouse grb2 gene: differential interaction of the Grb2 adaptor protein with epidermal growth factor and nerve growth factor receptors

21 January 2018

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Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor

21 January 2018

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Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

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Staurosporine causes epidermal growth factor to induce differentiation in PC12 cells via receptor up-regulation

21 January 2018

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IL-6-induced homodimerization of gp130 and associated activation of a tyrosine kinase

21 January 2018

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Signaling through the hematopoietic cytokine receptors.

21 January 2018

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Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

21 January 2018

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Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130

21 January 2018

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Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

21 January 2018

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Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

21 January 2018

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The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family

21 January 2018

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Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

21 January 2018

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Leukemia inhibitory factor and interleukin-6 trigger the same immediate early response, including tyrosine phosphorylation, upon induction of myeloid leukemia differentiation

21 January 2018

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The signalling pathways of interleukin-6 and gamma interferon converge by the activation of different transcription factors which bind to common responsive DNA elements

21 January 2018

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Interleukin-6 and the acute phase response

21 January 2018

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Cytokine signal transduction

21 January 2018

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Cytokines and the nervous system. I: Expression and recognition

21 January 2018

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Cytokines and the nervous system II: Actions and mechanisms of action

21 January 2018

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Interleukin-6 as a neurotrophic factor for promoting the survival of cultured catecholaminergic neurons in a chemically defined medium from fetal and postnatal rat midbrains

21 January 2018

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Neuronal differentiation factors/cytokines and synaptic plasticity

21 January 2018

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Interleukin-6 protects cultured rat hippocampal neurons against glutamate-induced cell death.

21 January 2018

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Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6

21 January 2018

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Site-specific hippocampal pathophysiology due to cerebral overexpression of interleukin-6 in transgenic mice.

21 January 2018

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PC12-E2 cells: a stable variant with altered responses to growth factor stimulation

21 January 2018

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Effect of nerve growth factor and fibroblast growth factor on PC12 cells: inhibition by orthovanadate

21 January 2018

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

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Cell-free activation of a DNA-binding protein by epidermal growth factor

21 January 2018

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Induction of neuronal differentiation in PC12 cells by B-cell stimulatory factor 2/interleukin 6

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.22.13023

Evidence for RNA synthesis-dependent and -independent pathways in stimulation of neurite outgrowth by nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.22.13023

STAT3 activation by cytokines utilizing gp130 and related transducers involves a secondary modification requiring an H7-sensitive kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.22.13023

Interleukin-6-induced serine phosphorylation of transcription factor APRF: evidence for a role in interleukin-6 target gene induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.22.13023

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.22.13023

Requirement of serine phosphorylation for formation of STAT-promoter complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.22.13023

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.22.13023

Acute-phase response factor, a nuclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.22.13023

Phosphorylation and internalization of gp130 occur after IL-6 activation of Jak2 kinase in hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.22.13023

The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.22.13023

Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.22.13023

Binding characteristics of ciliary neurotrophic factor to sympathetic neurons and neuronal cell lines

21 January 2018

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The alphas, betas, and kinases of cytokine receptor complexes

21 January 2018

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Phosphorylation of the human leukemia inhibitory factor (LIF) receptor by mitogen-activated protein kinase and the regulation of LIF receptor function by heterologous receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.22.13023

Activation of Fes tyrosine kinase by gp130, an interleukin-6 family cytokine signal transducer, and their association

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.22.13023

Synergistic induction of neurite outgrowth by nerve growth factor or epidermal growth factor and interleukin-6 in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.22.13023

Inhibition of MAP Kinase Kinase Blocks the Differentiation of PC-12 Cells Induced by Nerve Growth Factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.22.13023

The neurotrophins and their receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.22.13023

PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.22.13023

Characterization and isolation of proteolytically modified nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.22.13023

Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.22.13023

21 January 2018

Identifiers

DOI

10.1074/JBC.271.22.13023

1 reference

22 December 2017

PubMed ID

8662645

1 reference

22 December 2017