(Q46498440)

22 December 2017

title

Effects of elevated pCO2 and osmolality on growth of CHO cells and production of antibody-fusion protein B1: a case study (English)

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22 December 2017

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Marie M Zhu

1

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22 December 2017

Asti Goyal

2

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22 December 2017

Douglas L Rank

3

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22 December 2017

Sunil K Gupta

4

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22 December 2017

Thomas Vanden Boom

5

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22 December 2017

Steven S Lee

6

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22 December 2017

publication date

1 January 2005

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22 December 2017

number of pages

8

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inferred from page(s)

published in

Biotechnology Progress

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22 December 2017

volume

21

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22 December 2017

issue

1

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22 December 2017

page(s)

70-77

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22 December 2017

Effects of elevated pCO(2) and/or osmolality on the growth and recombinant tPA production of CHO cells

cites work

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7 January 2021

Effects of CO2 and osmolality on hybridoma cells: growth, metabolism and monoclonal antibody production

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7 January 2021

Growth, metabolic, and antibody production kinetics of hybridoma cell culture: 2. Effects of serum concentration, dissolved oxygen concentration, and medium pH in a batch reactor

1 reference

7 January 2021

Response of recombinant Chinese hamster ovary cells to hyperosmotic pressure: effect of Bcl-2 overexpression

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7 January 2021

Growth behavior of Chinese hamster ovary cells in a compact loop bioreactor. 2. Effects of medium components and waste products

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7 January 2021

Characterization of hybridoma cell responses to elevated pCO(2) and osmolality: intracellular pH, cell size, apoptosis, and metabolism

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7 January 2021

Effects of abrupt and gradual osmotic stress on antibody production and content in hybridoma cells that differ in production kinetics

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7 January 2021

Substantial overproduction of antibodies by applying osmotic pressure and sodium butyrate

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7 January 2021

CO(2) in large-scale and high-density CHO cell perfusion culture

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7 January 2021

Strategies for improved dCO2 removal in large-scale fed-batch cultures

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7 January 2021

Bicarbonate concentration and osmolality are key determinants in the inhibition of CHO cell polysialylation under elevated pCO2 or pH

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7 January 2021

Considerations for osmolality measurement under elevated pCO(2): comparison of vapor pressure and freezing point osmometry

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7 January 2021

Application of hypoosmolar medium to fed-batch culture of hybridoma cells for improvement of culture longevity

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7 January 2021

In pursuit of the optimal fed-batch process for monoclonal antibody production

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7 January 2021

Spontaneous decomposition of glutamine in cell culture media

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7 January 2021

Production of monoclonal antibody using free-suspended and immobilized hybridoma cells: Effect of serum

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7 January 2021

Effect of changes in the pH and carbon dioxide evolution rate on the measured respiratory quotient of fermentations.

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7 January 2021

Effects of osmoprotectant compounds on NCAM polysialylation under hyperosmotic stress and elevated pCO(2).

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7 January 2021

Hyperosmotic hbridoma cell cultures: Increased monoclonal antibody production with addition of glycine betaine

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7 January 2021

Effect of hypoosmotic stress on hybridoma cell growth and antibody production

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7 January 2021

Identifiers

DOI

10.1021/BP049815S

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22 December 2017

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22 December 2017