(Q46517046)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18582585%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

title

Selective block of IKs plays a significant role in MAP triangulation induced by IKr block in isolated rabbit heart (English)

1 reference

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9 January 2020

4

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9 January 2020

author name string

N C Guérard

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18582585%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

M Traebert

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18582585%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

W Suter

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18582585%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

publication date

8 June 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18582585%20AND%20SRC:MED&resulttype=core&format=json

Journal of Pharmacological and Toxicological Methods

9 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18582585%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

volume

58

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18582585%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

issue

1

1 reference

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9 January 2020

page(s)

32-40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18582585%20AND%20SRC:MED&resulttype=core&format=json

Gender differences in the slow delayed (IKs) but not in inward (IK1) rectifier K+ currents of canine Purkinje fibre cardiac action potential: key roles for IKs, beta-adrenoceptor stimulation, pacing rate and gender.

9 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Suppression of time-dependent outward current in guinea pig ventricular myocytes. Actions of quinidine and amiodarone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Interaction of different potassium channels in cardiac repolarization in dog ventricular preparations: role of repolarization reserve

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Effects of the chromanol 293B, a selective blocker of the slow, component of the delayed rectifier K+ current, on repolarization in human and guinea pig ventricular myocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Regional differences in the delayed rectifier current (IKr and IKs) contribute to the differences in action potential duration in basal left ventricular myocytes in guinea-pig

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Quinidine-induced open channel block of K+ current in rat ventricle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Anti-HERG activity and the risk of drug-induced arrhythmias and sudden death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Electrophysiological effects of myocardial stretch and mechanical determinants of stretch-activated arrhythmias

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Relative contributions of TRIaD and QT to proarrhythmia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Instability and triangulation of the action potential predict serious proarrhythmia, but action potential duration prolongation is antiarrhythmic

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Slow delayed rectifier potassium current (IKs) and the repolarization reserve.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Restricting excessive cardiac action potential and QT prolongation: a vital role for IKs in human ventricular muscle.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Molecular and cellular mechanisms of cardiac arrhythmias

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Pharmacological block of the slow component of the outward delayed rectifier current (I(Ks)) fails to lengthen rabbit ventricular muscle QT(c) and action potential duration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Combined pharmacological block of I(Kr) and I(Ks) increases short-term QT interval variability and provokes torsades de pointes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Density and kinetics of I(Kr) and I(Ks) in guinea pig and rabbit ventricular myocytes explain different efficacy of I(Ks) blockade at high heart rate in guinea pig and rabbit: implications for arrhythmogenesis in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Drug-induced long QT in isolated rabbit Purkinje fibers: importance of action potential duration, triangulation and early afterdepolarizations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Both beta-adrenergic receptor stimulation and cardiac tissue type have important roles in elucidating the functional effects of I(Ks) channel blockers in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

In-vitro experimental models for the risk assessment of antibiotic-induced QT prolongation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Potentiation of E-4031-induced torsade de pointes by HMR1556 or ATX-II is not predicted by action potential short-term variability or triangulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Cisapride-induced prolongation of cardiac action potential and early afterdepolarizations in rabbit Purkinje fibres.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Block of NA+ and K+ currents in rat ventricular myocytes by quinacainol and quinidine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Protecting the heart against arrhythmias: potassium current physiology and repolarization reserve

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Incidence and clinical features of the quinidine-associated long QT syndrome: implications for patient care

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Ranolazine: ion-channel-blocking actions and in vivo electrophysiological effects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Role of an inwardly rectifying potassium current in rabbit ventricular action potential

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Effects of quinidine on the sodium current of guinea pig ventricular myocytes. Evidence for a drug-associated rested state with altered kinetics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Blockade of IKs by HMR 1556 increases the reverse rate-dependence of refractoriness prolongation by dofetilide in isolated rabbit ventricles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Accumulation of slowly activating delayed rectifier potassium current (IKs) in canine ventricular myocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Chromanol 293B inhibits slowly activating delayed rectifier and transient outward currents in canine left ventricular myocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

The cardiac hERG/IKr potassium channel as pharmacological target: structure, function, regulation, and clinical applications

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

The role of the delayed rectifier component IKs in dog ventricular muscle and Purkinje fibre repolarization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Probing the contribution of IKs to canine ventricular repolarization: key role for beta-adrenergic receptor stimulation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

Detection of proarrhythmia in the female rabbit heart: blinded validation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2008.05.129

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.VASCN.2008.05.129

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18582585%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference