(Q46542921)

23 December 2017

title

Unique residues crucial for optimal editing in yeast cytoplasmic Leucyl-tRNA synthetase are revealed by using a novel knockout yeast strain (English)

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23 December 2017

author name string

Peng Yao

1

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23 December 2017

Xiao-Long Zhou

2

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23 December 2017

Ran He

3

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23 December 2017

Mei-Qin Xue

4

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23 December 2017

Yong-Gang Zheng

5

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23 December 2017

Yue-Fei Wang

6

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23 December 2017

En-Duo Wang

7

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23 December 2017

language of work or name

English

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publication date

11 June 2008

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23 December 2017

Journal of Biological Chemistry

published in

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23 December 2017

volume

283

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23 December 2017

issue

33

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23 December 2017

page(s)

22591-22600

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23 December 2017

Formation of two classes of tRNA synthetases in relation to editing functions and genetic code

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1 reference

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Aminoacyl-tRNA synthetases, the genetic code, and the evolutionary process

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Global effects of mistranslation from an editing defect in mammalian cells

21 January 2018

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Isolated CP1 domain of Escherichia coli leucyl-tRNA synthetase is dependent on flanking hinge motifs for amino acid editing activity

21 January 2018

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Leucyl-tRNA synthetase from the ancestral bacterium Aquifex aeolicus contains relics of synthetase evolution

21 January 2018

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Structural and mechanistic basis of pre- and posttransfer editing by leucyl-tRNA synthetase

21 January 2018

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Groups on the side chain of T252 in Escherichia coli leucyl-tRNA synthetase are important for discrimination of amino acids and cell viability

21 January 2018

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A conserved threonine within Escherichia coli leucyl-tRNA synthetase prevents hydrolytic editing of leucyl-tRNALeu

21 January 2018

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The crystal structure of leucyl-tRNA synthetase complexed with tRNALeu in the post-transfer-editing conformation

21 January 2018

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Inhibited cell growth and protein functional changes from an editing-defective tRNA synthetase

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Enlarging the amino acid set of Escherichia coli by infiltration of the valine coding pathway

21 January 2018

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Genetic code ambiguity. Cell viability related to the severity of editing defects in mutant tRNA synthetases

21 January 2018

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Post-transfer editing in vitro and in vivo by the beta subunit of phenylalanyl-tRNA synthetase

21 January 2018

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Elucidation of tRNA-dependent editing by a class II tRNA synthetase and significance for cell viability

21 January 2018

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Amino acid toxicities of Escherichia coli that are prevented by leucyl-tRNA synthetase amino acid editing

21 January 2018

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The C-terminal appended domain of human cytosolic leucyl-tRNA synthetase is indispensable in its interaction with arginyl-tRNA synthetase in the multi-tRNA synthetase complex

21 January 2018

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The anticodon loop is a major identity determinant of Saccharomyces cerevisiae tRNA(Leu).

21 January 2018

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Cross-species aminoacylation of tRNA with a long variable arm between Escherichia coli and Saccharomyces cerevisiae

21 January 2018

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The proofreading of hydroxy analogues of leucine and isoleucine by leucyl-tRNA synthetases from E. coli and yeast

21 January 2018

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An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site

21 January 2018

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

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21 January 2018

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Yeast cytoplasmic and mitochondrial methionyl-tRNA synthetases: two structural frameworks for identical functions

21 January 2018

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Active site mapping of yeast aspartyl-tRNA synthetase by in vivo selection of enzyme mutations lethal for cell growth.

21 January 2018

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Species barrier to RNA recognition overcome with nonspecific RNA binding domains

21 January 2018

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One of two genes encoding glycyl-tRNA synthetase in Saccharomyces cerevisiae provides mitochondrial and cytoplasmic functions

21 January 2018

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The proximal region of a noncatalytic eukaryotic seryl-tRNA synthetase extension is required for protein stability in vitro and in vivo.

21 January 2018

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In vivo selection of lethal mutations reveals two functional domains in arginyl-tRNA synthetase

21 January 2018

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The frequency of errors in protein biosynthesis

21 January 2018

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Dynamic aspects of vacuolar and cytosolic amino acid pools of Saccharomyces cerevisiae

21 January 2018

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Incorporation of norvaline at leucine positions in recombinant human hemoglobin expressed in Escherichia coli

21 January 2018

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Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration

21 January 2018

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Aminoacylation complex structures of leucyl-tRNA synthetase and tRNALeu reveal two modes of discriminator-base recognition

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M801181200

1 reference

23 December 2017

1 reference

23 December 2017