(Q46543702)

23 December 2017

title

Distinct mechanisms of neuronal apoptosis are triggered by antagonism of Bcl-2/Bcl-x(L) versus induction of the BH3-only protein Bim. (English)

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23 December 2017

author name string

Angela K Zimmermann

1

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23 December 2017

F Alexandra Loucks

2

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23 December 2017

Shoshona S Le

3

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23 December 2017

Brent D Butts

4

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23 December 2017

Maria L Florez-McClure

5

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23 December 2017

Ron J Bouchard

6

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23 December 2017

Kim A Heidenreich

7

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23 December 2017

Daniel A Linseman

8

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23 December 2017

language of work or name

English

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publication date

1 July 2005

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23 December 2017

Journal of Neurochemistry

published in

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23 December 2017

volume

94

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23 December 2017

issue

1

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23 December 2017

page(s)

22-36

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23 December 2017

Critical upstream signals of cytochrome C release induced by a novel Bcl-2 inhibitor

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VDAC2 inhibits BAK activation and mitochondrial apoptosis

21 January 2018

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Bax and Bak independently promote cytochrome C release from mitochondria

21 January 2018

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Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

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FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons

21 January 2018

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Control of Bcl-2 expression by reactive oxygen species

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The structure of Bcl-w reveals a role for the C-terminal residues in modulating biological activity

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Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

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A myocyte enhancer factor 2D (MEF2D) kinase activated during neuronal apoptosis is a novel target inhibited by lithium

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Glycogen synthase kinase-3beta phosphorylates Bax and promotes its mitochondrial localization during neuronal apoptosis.

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21 January 2018

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21 January 2018

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21 January 2018

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Increase in cytosolic Ca2+ levels through the activation of non-selective cation channels induced by oxidative stress causes mitochondrial depolarization leading to apoptosis-like death in Leishmania donovani promastigotes

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The permeability transition pore triggers Bax translocation to mitochondria during neuronal apoptosis

21 January 2018

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Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis

21 January 2018

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Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice

21 January 2018

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Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway

21 January 2018

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BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

21 January 2018

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Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activity

21 January 2018

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Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

21 January 2018

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BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

21 January 2018

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An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

21 January 2018

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10.1111/J.1471-4159.2005.03156.X

21 January 2018

Identifiers

DOI

1 reference

23 December 2017

1 reference

23 December 2017