(Q46549512)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18541525%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

title

Targeting of PED/PEA-15 molecular interaction with phospholipase D1 enhances insulin sensitivity in skeletal muscle cells (English)

1 reference

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8 January 2020

1 reference

1 reference

molecular interaction

1 reference

16

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8 January 2020

Simona Maria Monti

7

1 reference

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8 January 2020

author name string

Francesca Viparelli

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18541525%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Angela Cassese

2

1 reference

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8 January 2020

Nunzianna Doti

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18541525%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Flora Paturzo

4

1 reference

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8 January 2020

Daniela Marasco

5

1 reference

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8 January 2020

Nina A Dathan

6

1 reference

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8 January 2020

Giancarlo Basile

8

1 reference

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8 January 2020

Paola Ungaro

9

1 reference

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8 January 2020

Marco Sabatella

10

1 reference

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8 January 2020

Claudia Miele

11

1 reference

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8 January 2020

Raffaele Teperino

12

1 reference

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8 January 2020

Eduardo Consiglio

13

1 reference

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8 January 2020

Carlo Pedone

14

1 reference

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8 January 2020

Francesco Beguinot

15

1 reference

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8 January 2020

Menotti Ruvo

17

1 reference

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8 January 2020

language of work or name

English

0 references

publication date

9 June 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18541525%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

8 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18541525%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

volume

283

1 reference

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8 January 2020

issue

31

1 reference

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8 January 2020

page(s)

21769-21778

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18541525%20AND%20SRC:MED&resulttype=core&format=json

PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1-induced apoptosis

8 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803771200

The phosphoprotein protein PEA-15 inhibits Fas- but increases TNF-R1-mediated caspase-8 activity and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803771200

Omi/HtrA2 promotes cell death by binding and degrading the anti-apoptotic protein ped/pea-15

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803771200

Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803771200

Raised expression of the antiapoptotic protein ped/pea-15 increases susceptibility to chemically induced skin tumor development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803771200

PED/PEA-15 gene controls glucose transport and is overexpressed in type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803771200

The PEA15 gene is overexpressed and related to insulin resistance in healthy first-degree relatives of patients with type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803771200

Overexpression of the ped/pea-15 gene causes diabetes by impairing glucose-stimulated insulin secretion in addition to insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803771200

PED/PEA-15 regulates glucose-induced insulin secretion by restraining potassium channel expression in pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803771200

Protein kinase C (PKC)-alpha activation inhibits PKC-zeta and mediates the action of PED/PEA-15 on glucose transport in the L6 skeletal muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803771200

Recognition of ERK MAP kinase by PEA-15 reveals a common docking site within the death domain and death effector domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803771200

Protein kinase B/Akt binds and phosphorylates PED/PEA-15, stabilizing its antiapoptotic action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803771200

Phosphorylation of phosphoprotein enriched in astrocytes (PEA-15) regulates extracellular signal-regulated kinase-dependent transcription and cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803771200

Regulation of expression of phospholipase D1 and D2 by PEA-15, a novel protein that interacts with them

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803771200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803771200

Rapid formation of diacylglycerol from phosphatidylcholine: a pathway for generation of a second messenger

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803771200

Multiple members of the mitogen-activated protein kinase family are necessary for PED/PEA-15 anti-apoptotic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803771200

Tyrosine phosphorylation of phosphoinositide-dependent kinase 1 by the insulin receptor is necessary for insulin metabolic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803771200

Protein kinase C-zeta and protein kinase B regulate distinct steps of insulin endocytosis and intracellular sorting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803771200

Expression and purification of the D4 region of PLD1 and characterization of its interaction with PED-PEA15.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803771200

Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803771200

PKC-alpha regulates cardiac contractility and propensity toward heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803771200

Insulin-induced phospholipase D1 and phospholipase D2 activity in human embryonic kidney-293 cells mediated by the phospholipase Cγ and protein kinase Cα signalling cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M803771200

21 January 2018

Identifiers

DOI

10.1074/JBC.M803771200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18541525%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference