(Q46567373)

23 December 2017

title

Structural biology: Membrane enzyme cuts a fine figure (English)

1 reference

23 December 2017

1 reference

Michael S Wolfe

1

1 reference

23 December 2017

language of work or name

English

0 references

publication date

19 December 2012

1 reference

23 December 2017

published in

Nature

1 reference

23 December 2017

volume

493

1 reference

23 December 2017

issue

7430

1 reference

23 December 2017

page(s)

34-35

1 reference

23 December 2017

https://scigraph.springernature.com/pub.10.1038/nature11768

exact match

0 references

cites work

Intramembrane proteolysis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11768

Crystal structure of a rhomboid family intramembrane protease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11768

Structure of a site-2 protease family intramembrane metalloprotease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11768

Structure of a presenilin family intramembrane aspartate protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11768

Identification of signal peptide peptidase, a presenilin-type aspartic protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11768

Presenilins and γ-secretase: structure, function, and role in Alzheimer Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11768

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11768

Presenilin is required for activity and nuclear access of Notch in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11768

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11768

Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11768

Active gamma-secretase complexes contain only one of each component

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11768

Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11768

Dissociation between the processivity and total activity of γ-secretase: implications for the mechanism of Alzheimer's disease-causing presenilin mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11768

The mechanism of γ-Secretase dysfunction in familial Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11768

21 January 2018

Identifiers

DOI

10.1038/NATURE11768

1 reference

23 December 2017

Dimensions Publication ID

1051739333

0 references

1 reference

23 December 2017