(Q46577685)

23 December 2017

title

Induction of centrosome and chromosome aberrations by imatinib in vitro (English)

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23 December 2017

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5

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23 December 2017

author name string

Fabarius A

1

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23 December 2017

Giehl M

2

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23 December 2017

Frank O

3

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23 December 2017

Duesberg P

4

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23 December 2017

Hehlmann R

6

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23 December 2017

Seifarth W

7

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23 December 2017

publication date

1 September 2005

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23 December 2017

published in

Leukemia

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23 December 2017

volume

19

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23 December 2017

issue

9

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23 December 2017

page(s)

1573-1578

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23 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.leu.2403861

exact match

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cites work

Chronic myeloid leukemia

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ARG tyrosine kinase activity is inhibited by STI571.

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A small molecule-kinase interaction map for clinical kinase inhibitors

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Macrophage colony-stimulating factor receptor c-fms is a novel target of imatinib.

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The biology of CML blast crisis

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Philadelphia chromosome-negative cells with trisomy 8 after busulfan and interferon treatment of Ph1-positive chronic myelogenous leukemia

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Clonal Ph-negative hematopoiesis in CML after therapy with imatinib mesylate is frequently characterized by trisomy 8.

21 January 2018

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Hematopathologic and cytogenetic findings in imatinib mesylate-treated chronic myelogenous leukemia patients: 14 months' experience

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Report of 34 patients with clonal chromosomal abnormalities in Philadelphia-negative cells during imatinib treatment of Philadelphia-positive chronic myeloid leukemia.

21 January 2018

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Emergence of clonal cytogenetic abnormalities in Ph- cells in some CML patients in cytogenetic remission to imatinib but restoration of polyclonal hematopoiesis in the majority

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Clonal aberrations in Philadelphia chromosome negative hematopoiesis in patients with chronic myeloid leukemia treated with imatinib or interferon alpha

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Occurrence of additional chromosome aberrations in chronic myeloid leukemia patients treated with imatinib mesylate

21 January 2018

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Demonstration of Philadelphia chromosome negative abnormal clones in patients with chronic myelogenous leukemia during major cytogenetic responses induced by imatinib mesylate.

21 January 2018

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Response and resistance in 300 patients with BCR-ABL-positive leukemias treated with imatinib in a single center: a 4.5-year follow-up

21 January 2018

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Centrosome aberrations in chronic myeloid leukemia correlate with stage of disease and chromosomal instability

21 January 2018

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Centrosome aberrations--hen or egg in cancer initiation and progression?

21 January 2018

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Imatinib mesylate (STI571) inhibits growth of primitive malignant progenitors in chronic myelogenous leukemia through reversal of abnormally increased proliferation

21 January 2018

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Maintenance of normal in situ chromosomal features in long-term tissue cultures.

21 January 2018

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Proposed banding nomenclature for the Chinese hamster chromosomes (Cricetulus griseus)

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5-Azacytidine- and Hoechst-induced aneuploidy in Indian muntjac

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Gene expression profiling of Philadelphia chromosome (Ph)-negative CD34+ hematopoietic stem and progenitor cells of patients with Ph-positive CML in major molecular remission during therapy with imatinib

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p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

21 January 2018

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Functional interaction between DNA-PK and c-Abl in response to DNA damage

21 January 2018

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Interaction between ATM protein and c-Abl in response to DNA damage

21 January 2018

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Regulation of Rad51 function by c-Abl in response to DNA damage

21 January 2018

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Instability of chromosome structure in cancer cells increases exponentially with degrees of aneuploidy

21 January 2018

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Imatinib mesylate inhibits T-cell proliferation in vitro and delayed-type hypersensitivity in vivo

21 January 2018

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Squamous cutaneous epithelial cell carcinoma in two CML patients with progressive disease under imatinib treatment

21 January 2018

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The protein kinase complement of the human genome

21 January 2018

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Overexpression of mammalian Rad51 does not stimulate tumorigenesis while a dominant-negative Rad51 affects centrosome fragmentation, ploidy and stimulates tumorigenesis, in p53-defective CHO cells.

21 January 2018

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Genetic interactions between RAD51 and its paralogues for centrosome fragmentation and ploidy control, independently of the sensitivity to genotoxic stresses

21 January 2018

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Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM.

21 January 2018

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Distinct intracellular localization of Lck and Fyn protein tyrosine kinases in human T lymphocytes

21 January 2018

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Polo-like kinases (Plks) and cancer

21 January 2018

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Aurora kinases link chromosome segregation and cell division to cancer susceptibility

21 January 2018

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Acute myeloblastic leukaemia without Philadelphia chromosome developing after interferon therapy for chronic myelocytic leukaemia with Philadelphia chromosome

21 January 2018

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7 January 2021

Trisomy 8 in Philadelphia chromosome (Ph1)-negative cells in the course of Ph1-positive chronic myelocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403861

7 January 2021

A second case of trisomy 8 in Philadelphia chromosome (Ph)-negative cells during the course of Ph-positive chronic myelocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403861

7 January 2021

Determination of cell fate by c-Abl activation in the response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403861

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2403861

1 reference

23 December 2017

PubMed ID

15990860

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23 December 2017