(Q46579855)

English

Protective effect of the endothelin antagonist CPU0213 against isoprenaline-induced heart failure by suppressing abnormal expression of leptin, calcineurin and SERCA2a in rats

scientific article published in June 2008

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/18498710

Protective effect of the endothelin antagonist CPU0213 against isoprenaline-induced heart failure by suppressing abnormal expression of leptin, calcineurin and SERCA2a in rats (English)

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/18498710

author name string

Ming Xu

1

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/18498710

Hui Ji

2

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/18498710

De-Zai Dai

3

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/18498710

Xiao-Yun Tang

4

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/18498710

Yin Dai

5

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/18498710

publication date

1 June 2008

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/18498710

Journal of Pharmacy and Pharmacology

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/18498710

60

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/18498710

6

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/18498710

739-745

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/18498710

Disruption of leptin signaling contributes to cardiac hypertrophy independently of body weight in mice

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Beta-blockers of the third generation inhibit endothelin-1 liberation, mRNA production and proliferation of human coronary smooth muscle and endothelial cells

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

A20 is dynamically regulated in the heart and inhibits the hypertrophic response

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Leptin regulates cardiomyocyte contractile function through endothelin-1 receptor-NADPH oxidase pathway

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Normalization of the calcineurin pathway underlies the regression of hypertensive hypertrophy induced by Na+/H+ exchanger-1 (NHE-1) inhibition

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Reversal of isoproterenol-induced downregulation of phospholamban and FKBP12.6 by CPU0213-mediated antagonism of endothelin receptors

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Endothelin1-induced Ca(2+) mobilization is altered in calvarial osteoblastic cells of Cx43(+/- ) mice.

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

SERCA2a in heart failure: role and therapeutic prospects

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Obesity hypertension: role of leptin and sympathetic nervous system

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Leptin affects adenylate cyclase activity in H9c2 cardiac cell line: effects of short- and long-term exposure

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Endothelin receptor antagonists: an overview of their synthesis and structure-activity relationship

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Activation of peroxisome proliferator-activated receptor-alpha decreases endothelin-1-induced p38 mitogen-activated protein kinase activation in cardiomyocytes

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Intracoronary endothelin-1 infusion combined with systemic isoproterenol treatment: antagonistic arrhythmogenic effects

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Endothelin-1-induced proliferation of human endothelial cells depends on activation of K+ channels and Ca+ influx

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Leptin and adiponectin stimulate the release of proinflammatory cytokines and prostaglandins from human placenta and maternal adipose tissue via nuclear factor-kappaB, peroxisomal proliferator-activated receptor-gamma and extracellularly regulated k

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Calcineurin inhibition normalizes beta-adrenergic responsiveness in the spontaneously hypertensive rat.

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Calcineurin-GATA4 pathway is involved in beta-adrenergic agonist-responsive endothelin-1 transcription in cardiac myocytes

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Leptin changes Ca2+/calmodulin-dependent response and up-regulates the gene expression of calcineurin in rat hypothalamus

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Upregulation of leptin pathway correlates with abnormal expression of SERCA2a, phospholamban and the endothelin pathway in heart failure and reversal by CPU86017.

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Rat heart is a site of leptin production and action

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Effect of endothelin receptor antagonist bosentan on plasma leptin concentration in acute myocardial infarction in rats

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

The obesity-associated peptide leptin induces hypertrophy in neonatal rat ventricular myocytes

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Lack of inducible NO synthase reduces oxidative stress and enhances cardiac response to isoproterenol in mice with deoxycorticosterone acetate-salt hypertension

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Endothelin-1 is an essential co-factor for beta2-adrenergic receptor-induced proliferation of human cardiac fibroblasts.

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Improvement of chronic heart failure by dexamethasone is not associated with downregulation of leptin in rats

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Endothelin-1 stimulates leptin production in adipocytes

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Leptin induces hypertrophy via endothelin-1-reactive oxygen species pathway in cultured neonatal rat cardiomyocytes.

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Altered intracellular Ca2+ handling in heart failure

1 reference

https://api.crossref.org/works/10.1211%2FJPP.60.6.0009

21 January 2018

Identifiers

10.1211/JPP.60.6.0009

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/18498710

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/18498710

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