(Q46595664)

23 December 2017

review article

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title

Changing the end: antigenic variation orchestrated at the telomeres of African trypanosomes (English)

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23 December 2017

author name string

Rudenko G

series ordinal

1

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23 December 2017

Cross M

series ordinal

2

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23 December 2017

Borst P

series ordinal

3

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23 December 2017

publication date

1 March 1998

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23 December 2017

published in

Trends in Microbiology

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23 December 2017

volume

6

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23 December 2017

page(s)

113-116

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23 December 2017

issue

3

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23 December 2017

Antigenic variation in African trypanosomes

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The relative significance of mechanisms of antigenic variation in African trypanosomes

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Inactivation of transcription by UV irradiation of T. brucei provides evidence for a multicistronic transcription unit including a VSG gene

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The genes and transcripts of an antigen gene expression site from T. brucei

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DNA rearrangements associated with multiple consecutive directed antigenic switches in Trypanosoma brucei

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Transcriptional regulation of metacyclic variant surface glycoprotein gene expression during the life cycle of Trypanosoma brucei.

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A monocistronic transcript for a trypanosome variant surface glycoprotein

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An estimate of the size of the metacyclic variable antigen repertoire of Trypanosoma brucei rhodesiense

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7 January 2021

Metacyclic variant surface glycoprotein genes of Trypanosoma brucei subsp. rhodesiense are activated in situ, and their expression is transcriptionally regulated

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Distinct, developmental stage-specific activation mechanisms of trypanosome VSG genes.

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Chromosome organization of the protozoan Trypanosoma brucei

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7 January 2021

Chromosome structure: DNA nucleotide sequence elements of a subset of the minichromosomes of the protozoan Trypanosoma brucei

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7 January 2021

Telomere exchange can be an important mechanism of variant surface glycoprotein gene switching in Trypanosoma brucei

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7 January 2021

Gene conversions mediating antigenic variation in Trypanosoma brucei can occur in variant surface glycoprotein expression sites lacking 70-base-pair repeat sequences

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7 January 2021

Active late-appearing variable surface antigen genes in Trypanosoma equiperdum are constructed entirely from pseudogenes

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7 January 2021

Antigenic diversity by the recombination of pseudogenes

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7 January 2021

Point mutations are associated with a gene duplication leading to the bloodstream reexpression of a trypanosome metacyclic VSG.

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Is point mutagenesis a mechanism for antigenic variation in Trypanosoma brucei?

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Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription

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7 January 2021

Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage

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7 January 2021

A ribosomal DNA promoter replacing the promoter of a telomeric VSG gene expression site can be efficiently switched on and off in T. brucei

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7 January 2021

A developmentally regulated position effect at a telomeric locus in Trypanosoma brucei.

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7 January 2021

The putative promoter for a metacyclic VSG gene in African trypanosomes.

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7 January 2021

Two simultaneously active VSG gene transcription units in a single Trypanosoma brucei variant

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7 January 2021

Stable expression of two variable surface glycoproteins by cloned Trypanosoma equiperdum

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7 January 2021

Release of the variant surface glycoprotein during differentiation of bloodstream to procyclic forms of Trypanosoma brucei

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Degradation, recycling, and shedding of Trypanosoma brucei variant surface glycoprotein

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7 January 2021

Expression of two variant surface glycoproteins on individual African trypanosomes during antigen switching.

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7 January 2021

Analysis of Trypanosoma brucei vsg expression site switching in vitro

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Stable expression of mosaic coats of variant surface glycoproteins in Trypanosoma brucei

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Transient activity assays of the Trypanosoma brucei variant surface glycoprotein gene promoter: control of gene expression at the posttranscriptional level

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7 January 2021

A detailed mutational analysis of the VSG gene expression site promoter.

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7 January 2021

The PARP promoter of Trypanosoma brucei is developmentally regulated in a chromosomal context.

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7 January 2021

Manipulation of the vsg co-transposed region increases expression-site switching in Trypanosoma brucei.

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7 January 2021

beta-D-glucosyl-hydroxymethyluracil: a novel modified base present in the DNA of the parasitic protozoan T. brucei

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7 January 2021

The telomeric GGGTTA repeats of Trypanosoma brucei contain the hypermodified base J in both strands

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7 January 2021

Localization of the modified base J in telomeric VSG gene expression sites of Trypanosoma brucei

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7 January 2021

Membrane modifications in erythrocytes parasitized by Plasmodium falciparum

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7 January 2021

Translocation of surface antigen genes to a unique telomeric expression site in Pneumocystis carinii

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7 January 2021

10.1016/S0966-842X(97)01200-6

Identifiers

DOI

1 reference

23 December 2017

PubMed ID

9582937

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23 December 2017