(Q46605088)

English

Short-term inhibition of peroxisome proliferator-activated receptor-gamma coactivator-1alpha expression reverses diet-induced diabetes mellitus and hepatic steatosis in mice.

scientific article published on 16 July 2005

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16025253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Short-term inhibition of peroxisome proliferator-activated receptor-gamma coactivator-1alpha expression reverses diet-induced diabetes mellitus and hepatic steatosis in mice (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16025253%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

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Eliana P Araújo

2

1 reference

Europe PubMed Central

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31 December 2019

author name string

C T De Souza

1

1 reference

Europe PubMed Central

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31 December 2019

P O Prada

3

1 reference

Europe PubMed Central

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31 December 2019

M J A Saad

4

1 reference

Europe PubMed Central

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31 December 2019

A C Boschero

5

1 reference

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31 December 2019

L A Velloso

6

1 reference

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31 December 2019

publication date

16 July 2005

1 reference

Europe PubMed Central

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31 December 2019

1 reference

Europe PubMed Central

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31 December 2019

48

1 reference

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31 December 2019

9

1 reference

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31 December 2019

1860-1871

1 reference

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31 December 2019

https://scigraph.springernature.com/pub.10.1007/s00125-005-1866-4

0 references

Direct binding and In vivo regulation of the fission yeast p21-activated kinase shk1 by the SH3 domain protein scd2.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-005-1866-4

21 January 2018

Obesity wars: molecular progress confronts an expanding epidemic

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ability of insulin to modulate hepatic glucose production in aging rats is impaired by fat accumulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variation in type 2 diabetes--related traits in mouse strains susceptible to diet-induced obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Are animal models of diabetes relevant to the study of the genetics of non-insulin-dependent diabetes in humans?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acquirement of brown fat cell features by human white adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary fat interacts with QTLs controlling induction ofPgc-1α andUcp1during conversion of white to brown fat

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of blood glucose using an oxidase-peroxidase system with a non-carcinogenic chromogen

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CREB controls hepatic lipid metabolism through nuclear hormone receptor PPAR-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New drug targets for type 2 diabetes and the metabolic syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation analysis of peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global and societal implications of the diabetes epidemic

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cold exposure induces tissue-specific modulation of the insulin-signalling pathway in Rattus norvegicus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin resistance: from benign to type 2 diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A method for the simultaneous measurement of insulin release and B cell membrane potential in single mouse islets of Langerhans

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Restoration of sterol-regulatory-element-binding protein-1c gene expression in HepG2 cells by peroxisome-proliferator-activated receptor-gamma co-activator-1alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced expression of PGC-1 and insulin-signaling molecules in adipose tissue is associated with insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of beta cell energy metabolism and insulin release by PGC-1alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationships between insulin secretion, insulin metabolism and insulin resistance in mild glucose intolerance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced Expression of FOXC2 and Brown Adipogenic Genes in Human Subjects with Insulin Resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Obesity: the integrated roles of environment and genetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CREB regulates hepatic gluconeogenesis through the coactivator PGC-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mediators of hepatic steatosis and liver injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor gamma coactivator-1-dependent uncoupling protein-2 expression in pancreatic islets of rats: a novel pathway for neural control of insulin secretion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-cell dysfunction and failure in type 2 diabetes: potential mechanisms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cold-induced PGC-1alpha expression modulates muscle glucose uptake through an insulin receptor/Akt-independent, AMPK-dependent pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16025253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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