(Q46628262)

English

Second-generation antipsychotic drugs, olanzapine, quetiapine, and clozapine enhance neurite outgrowth in PC12 cells via PI3K/AKT, ERK, and pertussis toxin-sensitive pathways

scientific article published in January 2005

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16055946

Second-generation antipsychotic drugs, olanzapine, quetiapine, and clozapine enhance neurite outgrowth in PC12 cells via PI3K/AKT, ERK, and pertussis toxin-sensitive pathways (English)

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16055946

1 reference

based on heuristic

inferred from title

author name string

Xiao-Hong Lu

1

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16055946

Donard S Dwyer

2

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16055946

publication date

1 January 2005

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16055946

Journal of Molecular Neuroscience

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16055946

27

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16055946

1

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16055946

43-64

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16055946

Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

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The phosphatidylinositol-3 kinase (PI3K)-Akt pathway suppresses neurite branch formation in NGF-treated PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

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Stimulation by antipsychotic agents of mitogen-activated protein kinase (MAPK) coupled to cloned, human (h)serotonin (5-HT)(1A) receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NS-417, a novel compound with neurotrophic-like effects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effects of atypical antipsychotic drugs on PC12 cells after serum withdrawal

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

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Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxicity of conventional and atypical antipsychotic drugs in relation to glucose metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

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Evidence that antipsychotic drugs are inverse agonists at D2 dopamine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NS 1231, a novel compound with neurotrophic-like effects in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

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Overexpression of Akt inhibits NGF-induced growth arrest and neuronal differentiation of PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal survival induced by neurotrophins requires calmodulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

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Chronic haloperidol treatment differentially affects the expression of synaptic and neuronal plasticity-associated genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

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Characteristics of the cytotoxic effects of the phenothiazine class of calmodulin antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calmodulin mediates brain-derived neurotrophic factor cell survival signaling upstream of Akt kinase in embryonic neocortical neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of chronic haloperidol and clozapine treatment on neurogenesis in the adult rat hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

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Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Striatal volume changes in the rat following long-term administration of typical and atypical antipsychotic drugs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Initiation and maintenance of NGF-stimulated neurite outgrowth requires activation of a phosphoinositide 3-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue concentrations of clozapine and its metabolites in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antipsychotic drugs clozapine and olanzapine upregulate bcl-2 mRNA and protein in rat frontal cortex and hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inverse agonist properties of atypical antipsychotic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible involvement of the ERK signaling cascade in bipolar disorder: behavioral leads from the study of mutant mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and tissue distribution of olanzapine in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

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Neurite outgrowth of PC12 cells is suppressed by wortmannin, a specific inhibitor of phosphatidylinositol 3-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal glucose metabolism and schizophrenia: therapeutic prospects?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inverse agonist activity of atypical antipsychotic drugs at human 5-hydroxytryptamine2C receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt pathway mediates a cGMP-dependent survival role of nitric oxide in cerebellar granule neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuropathological effects of antipsychotic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective effects of olanzapine on methamphetamine-induced neurotoxicity are associated with an inhibition of hyperthermia and prevention of Bcl-2 decrease in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of phosphatidylinositol 3-kinase in neural cell adhesion molecule-mediated neuronal differentiation and survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/16055946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1385/JMN:27:1:043

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16055946

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16055946

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