(Q46643296)

23 December 2017

title

Expression of proteinase-activated receptor 2 on human primary gastrointestinal myofibroblasts and stimulation of prostaglandin synthesis (English)

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23 December 2017

author name string

Michelle L Seymour

1

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23 December 2017

David G Binion

2

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23 December 2017

Steven J Compton

3

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23 December 2017

Morley D Hollenberg

4

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23 December 2017

Wallace K MacNaughton

5

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23 December 2017

publication date

1 July 2005

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23 December 2017

Canadian Journal of Physiology and Pharmacology

published in

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23 December 2017

volume

83

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23 December 2017

issue

7

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23 December 2017

page(s)

605-616

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23 December 2017

Extrapancreatic trypsin-2 cleaves proteinase-activated receptor-2.

cites work

1 reference

Trypsin stimulates proteinase-activated receptor-2-dependent and -independent activation of mitogen-activated protein kinases

21 January 2018

1 reference

Immune system control of rat and rabbit colonic electrolyte transport. Role of prostaglandins and enteric nervous system

21 January 2018

1 reference

Fibroblasts modulate intestinal secretory responses to inflammatory mediators

21 January 2018

1 reference

Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2

21 January 2018

1 reference

Glycosylation and the activation of proteinase-activated receptor 2 (PAR(2)) by human mast cell tryptase

21 January 2018

1 reference

Restricted ability of human mast cell tryptase to activate proteinase-activated receptor-2 in rat aorta

21 January 2018

1 reference

Mast cell tryptase regulates rat colonic myocytes through proteinase-activated receptor 2.

21 January 2018

1 reference

Protease-activated receptors start a family

21 January 2018

1 reference

Characterization of protease-activated receptor-2 immunoreactivity in normal human tissues

21 January 2018

1 reference

Thrombin induces IL-6 but not TNFalpha secretion by mouse mast cells: threshold-level thrombin receptor and very low level FcepsilonRI signaling synergistically enhance IL-6 secretion

21 January 2018

1 reference

Protease-activated receptors and their role in IL-6 and NF-IL-6 expression in human gingival fibroblasts

21 January 2018

1 reference

Evaluation of the substrate specificity of human mast cell tryptase beta I and demonstration of its importance in bacterial infections of the lung

21 January 2018

1 reference

Protease-activated receptor 3 is a second thrombin receptor in humans

21 January 2018

1 reference

Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target

21 January 2018

1 reference

A dual thrombin receptor system for platelet activation

21 January 2018

1 reference

Production of prostaglandinE2 via bile acid is enhanced by trypsin and acid in normal human esophageal epithelial cells

21 January 2018

1 reference

Luminal trypsin may regulate enterocytes through proteinase-activated receptor 2.

21 January 2018

1 reference

Expression of trypsin by epithelial cells of various tissues, leukocytes, and neurons in human and mouse

21 January 2018

1 reference

Role of PGE(2) in protease-activated receptor-1, -2 and -4 mediated relaxation in the mouse isolated trachea

21 January 2018

1 reference

Regulation of COX-2 expression in human intestinal myofibroblasts: mechanisms of IL-1-mediated induction

21 January 2018

1 reference

Interactions of mast cell tryptase with thrombin receptors and PAR-2.

21 January 2018

1 reference

PAR3 is a cofactor for PAR4 activation by thrombin

21 January 2018

1 reference

Molecular cloning of a potential proteinase activated receptor

21 January 2018

1 reference

cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase

21 January 2018

1 reference

Inflammation and specialized intestinal metaplasia of cardiac mucosa is a manifestation of gastroesophageal reflux disease.

21 January 2018

1 reference

Evidence for the presence of a protease-activated receptor distinct from the thrombin receptor in human keratinocytes

21 January 2018

1 reference

What is the secretory potential of submucosal mucous glands within the human gullet in health and disease?

21 January 2018

1 reference

Reaction of mast cell proteases tryptase and chymase with protease activated receptors (PARs) on keratinocytes and fibroblasts

21 January 2018

1 reference

PAR1-dependent and independent increases in COX-2 and PGE2 in human colonic myofibroblasts stimulated by thrombin

21 January 2018

1 reference

Cyclooxygenase 2 expression in Barrett's esophagus and adenocarcinoma: Ex vivo induction by bile salts and acid exposure

21 January 2018

1 reference

Role of intestinal mast cells in modulating gastrointestinal pathophysiology

21 January 2018

1 reference

Proinflammatory cytokines differentially modulate their own expression in human intestinal mucosal mesenchymal cells

21 January 2018

1 reference

Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis

21 January 2018

1 reference

Proteinase-activated receptor 2 (PAR2)-activating peptides: identification of a receptor distinct from PAR2 that regulates intestinal transport

21 January 2018

1 reference

Post-translational and activation-dependent modifications of the G protein-coupled thrombin receptor.

21 January 2018

1 reference

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

21 January 2018

1 reference

Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis

21 January 2018

1 reference

Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing

21 January 2018

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Cloning and characterization of human protease-activated receptor 4

21 January 2018

1 reference

Complementary DNA cloning and sequencing of rat enteropeptidase and tissue distribution of its mRNA.

21 January 2018

1 reference

Increased Levels of Prostaglandins and Nitric Oxide in Esophageal Mucosa of Children with Reflux Esophagitis

21 January 2018

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21 January 2018

Identifiers

DOI

10.1139/Y05-046

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23 December 2017

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23 December 2017