(Q46645109)

English

Synergic Effects of Doxorubicin and Melatonin on Apoptosis and Mitochondrial Oxidative Stress in MCF-7 Breast Cancer Cells: Involvement of TRPV1 Channels

scientific article published on 2 November 2015

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26525975

Synergic Effects of Doxorubicin and Melatonin on Apoptosis and Mitochondrial Oxidative Stress in MCF-7 Breast Cancer Cells: Involvement of TRPV1 Channels (English)

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26525975

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1 reference

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author name string

Pınar Aslan Koşar

1

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26525975

Mustafa Nazıroğlu

2

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26525975

İshak Suat Övey

3

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26525975

Bilal Çiğ

4

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26525975

publication date

2 November 2015

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Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26525975

number of pages

12

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Journal of Membrane Biology

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Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26525975

249

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Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26525975

1-2

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Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26525975

129-140

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26525975

https://scigraph.springernature.com/pub.10.1007/s00232-015-9855-0

0 references

Pro-oxidant effect of melatonin in tumour leucocytes: relation with its cytotoxic and pro-apoptotic effects

1 reference

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The capsaicin receptor: a heat-activated ion channel in the pain pathway

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Melatonin modulates apoptosis and TRPM2 channels in transfected cells activated by oxidative stress.

1 reference

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A splice variant of the human ion channel TRPM2 modulates neuroblastoma tumor growth through hypoxia-inducible factor (HIF)-1/2α.

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Investigation of the effects of distance from sources on apoptosis, oxidative stress and cytosolic calcium accumulation via TRPV1 channels induced by mobile phones and Wi-Fi in breast cancer cells

1 reference

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Melatonin receptors in humans: biological role and clinical relevance

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Expression and putative functions of melatonin receptors in malignant cells and tissues

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Melatonin reduces apoptosis induced by calcium signaling in human leukocytes: Evidence for the involvement of mitochondria and Bax activation

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The inhibition of TNF-α-induced leucocyte apoptosis by melatonin involves membrane receptor MT1/MT2 interaction.

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The anticancer agent doxorubicin disrupts mitochondrial energy metabolism and redox balance in skeletal muscle

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TNFα-induced apoptosis in human myeloid cell lines HL-60 and K562 is dependent of intracellular ROS generation.

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Mitochondrial catastrophe during doxorubicin-induced cardiotoxicity: a review of the protective role of melatonin

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Capsaicin mediates apoptosis in human nasopharyngeal carcinoma NPC-TW 039 cells through mitochondrial depolarization and endoplasmic reticulum stress

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N-acetylcysteine modulates doxorubicin-induced oxidative stress and antioxidant vitamin concentrations in liver of rats

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N-acetyl cysteine reduces oxidative toxicity, apoptosis, and calcium entry through TRPV1 channels in the neutrophils of patients with polycystic ovary syndrome

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

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New molecular mechanisms on the activation of TRPM2 channels by oxidative stress and ADP-ribose

1 reference

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Molecular role of catalase on oxidative stress-induced Ca(2+) signaling and TRP cation channel activation in nervous system

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Selenium and high dose vitamin E administration protects cisplatin-induced oxidative damage to renal, liver and lens tissues in rats.

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Melatonin modulates wireless (2.45 GHz)-induced oxidative injury through TRPM2 and voltage gated Ca(2+) channels in brain and dorsal root ganglion in rat.

1 reference

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Rapid and transient stimulation of intracellular reactive oxygen species by melatonin in normal and tumor leukocytes.

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'TRPing' synaptic ribbon function in the rat pineal gland: neuroendocrine regulation involves the capsaicin receptor TRPV1.

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CaMKII-dependent SR Ca leak contributes to doxorubicin-induced impaired Ca handling in isolated cardiac myocytes

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Role of oxidants on calcium and sodium movement in healthy and diseased cardiac myocytes

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Mechanisms of caspase activation and inhibition during apoptosis

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Melatonin suppresses doxorubicin-induced premature senescence of A549 lung cancer cells by ameliorating mitochondrial dysfunction

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Capsazepine, a TRPV1 antagonist, sensitizes colorectal cancer cells to apoptosis by TRAIL through ROS-JNK-CHOP-mediated upregulation of death receptors

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Selenium modulates oxidative stress-induced cell apoptosis in human myeloid HL-60 cells through regulation of calcium release and caspase-3 and -9 activities.

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Melatonin potentiates chemotherapy-induced cytotoxicity and apoptosis in rat pancreatic tumor cells

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Transient receptor potential vanilloid 1 expression and functionality in mcf-7 cells: a preliminary investigation.

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Consequences of activating the calcium-permeable ion channel TRPV1 in breast cancer cells with regulated TRPV1 expression

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Reduction in traumatic brain injury-induced oxidative stress, apoptosis, and calcium entry in rat hippocampus by melatonin: Possible involvement of TRPM2 channels

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Doxorubicin treatment induces tumor cell death followed by immunomodulation in a murine neuroblastoma model

1 reference

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12 December 2020

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Hypericum perforatum Attenuates Spinal Cord Injury-Induced Oxidative Stress and Apoptosis in the Dorsal Root Ganglion of Rats: Involvement of TRPM2 and TRPV1 Channels

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Decreased expression of the melatonin receptor 1 in human colorectal adenocarcinomas

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Melatonin: adjuvant therapy of malignant tumors.

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Identifiers

10.1007/S00232-015-9855-0

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26525975

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/26525975

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