(Q46649720)

English

Cancer dose--response assessment for acrylonitrile based upon rodent brain tumor incidence: use of epidemiologic, mechanistic, and pharmacokinetic support for nonlinearity

scientific article published in October 2005

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16099568

Cancer dose--response assessment for acrylonitrile based upon rodent brain tumor incidence: use of epidemiologic, mechanistic, and pharmacokinetic support for nonlinearity (English)

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16099568

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

Kirman CR

1

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16099568

Gargas ML

2

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16099568

Marsh GM

3

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16099568

Strother DE

4

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16099568

Klaunig JE

5

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16099568

Collins JJ

6

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16099568

Deskin R

7

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16099568

language of work or name

0 references

publication date

1 October 2005

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16099568

Regulatory Toxicology and Pharmacology

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16099568

43

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16099568

1

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16099568

85-103

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16099568

Molecular interaction of [2,3-14C] acrylonitrile with DNA in gastric tissue of rat

1 reference

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Cyanide-induced lipid peroxidation in different organs: subcellular distribution and hydroperoxide generation in neuronal cells

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Biological markers of acute acrylonitrile intoxication in rats as a function of dose and time.

1 reference

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Dose dependence of covalent binding of acrylonitrile to tissue protein and globin in rats.

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Primary brain tumours in Fischer 344 rats chronically exposed to acrylonitrile in their drinking-water

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Comparative metabolism and disposition of acrylonitrile and methacrylonitrile in rats

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Tissue-specific genotoxic effects of acrylamide and acrylonitrile

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Mortality patterns among workers exposed to acrylamide.

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Metabolism of organonitriles to cyanide by rat nasal tissue enzymes

1 reference

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Sodium thiosulfate protects against acrylonitrile-induced elevation of glial fibrillary acidic protein levels by replenishing glutathione

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The effects of acrylonitrile on hemoglobin and red cell metabolism

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In vivo interactions of acrylonitrile with macromolecules in rats

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Urinary metabolites of [1,2,3-13C]acrylonitrile in rats and mice detected by 13C nuclear magnetic resonance spectroscopy.

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Three-generation reproduction study of rats receiving acrylonitrile in drinking water

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A physiologically based dosimetry description of acrylonitrile and cyanoethylene oxide in the rat.

1 reference

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Acrylonitrile is a multisite carcinogen in male and female B6C3F1 mice

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Effect of oxidative DNA damage in promoter elements on transcription factor binding

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Induction of oxidative stress in rat brain by acrylonitrile (ACN).

1 reference

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7 January 2021

Chronic toxicity and oncogenic dose-response effects of lifetime oral acrylonitrile exposure to Fischer 344 rats

1 reference

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7 January 2021

Comparative chronic toxicity and carcinogenicity of acrylonitrile by drinking water and oral intubation to Spartan Sprague-Dawley rats

1 reference

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7 January 2021

Human Hepatic CYP2E1 Expression during Development

1 reference

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7 January 2021

Induction of oxidative stress and oxidative damage in rat glial cells by acrylonitrile

1 reference

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7 January 2021

The effect of acrylonitrile on gap junctional intercellular communication in rat astrocytes

1 reference

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7 January 2021

Species differences in the hydrolysis of 2-cyanoethylene oxide, the epoxide metabolite of acrylonitrile.

1 reference

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7 January 2021

Epoxidation of acrylonitrile by rat and human cytochromes P450.

1 reference

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7 January 2021

Refinement and verification of the physiologically based dosimetry description for acrylonitrile in rats.

1 reference

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7 January 2021

Improving cancer dose-response characterization by using physiologically based pharmacokinetic modeling: an analysis of pooled data for acrylonitrile-induced brain tumors to assess cancer potency in the rat.

1 reference

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7 January 2021

Induction of cyclooxygenase-2 in brain during acute and chronic ethanol treatment and ethanol withdrawal

1 reference

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7 January 2021

Mutagenicity of acrylonitrile in mouse

1 reference

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7 January 2021

Mutagenicity of vinyl compounds in salmonella typhimurium

1 reference

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Dose-response relationships in chemical carcinogenesis: superposition of different mechanisms of action, resulting in linear-nonlinear curves, practical thresholds, J-shapes

1 reference

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7 January 2021

Long-term carcinogenicity bioassays on acrylonitrile administered by inhalation and by ingestion to Sprague-Dawley rats

1 reference

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7 January 2021

Reevaluation of lung cancer risk in the acrylonitrile cohort study of the National Cancer Institute and the National Institute for Occupational Safety and Health

2 references

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7 January 2021

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Possible role of hydroxyl radicals in the oxidation of dichloroacetonitrile by Fenton-like reaction

1 reference

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Acrylonitrile enhances H2O2-mediated DNA damage via nitrogen-centered radical formation

1 reference

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7 January 2021

Epidemiologic study of workers exposed to acrylonitrile: an update

1 reference

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7 January 2021

Effect of glutathione depletion on the irreversible association of acrylonitrile with tissue macromolecules after oral administration to rats

1 reference

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7 January 2021

Effect of glutathione depletion on the uptake of acrylonitrile vapors and on its irreversible association with tissue macromolecules

1 reference

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Mutagenicity of acrylonitrile and its metabolite 2-cyanoethylene oxide in human lymphoblasts in vitro

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Cancer occurrence among workers exposed to acrylonitrile

1 reference

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Occupational exposure to vinyl chloride, acrylonitrile and styrene and lung cancer risk (europe).

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Reconciling animal and human data in a cancer risk assessment of acrylonitrile

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A risk assessment for occupational acrylonitrile exposure using epidemiology data

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Prolonged cyclooxygenase-2 induction in neurons and glia following traumatic brain injury in the rat.

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Role of cytochrome P450 2E1 in the metabolism of acrylamide and acrylonitrile in mice

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Mortality update of workers exposed to acrylonitrile in The Netherlands

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Physiologically based pharmacokinetic model parameter estimation and sensitivity and variability analyses for acrylonitrile disposition in humans

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Influence of polymorphisms of the human glutathione transferases and cytochrome P450 2E1 enzyme on the metabolism and toxicity of ethylene oxide and acrylonitrile

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Possible impact of human CYP2E1 polymorphisms on the metabolism of acrylonitrile

1 reference

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Biological considerations for combining carcinogenicity data for quantitative risk assessment

1 reference

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Mutagenicity of acrylonitrile (cyanoethylene) in Escherichia coli

1 reference

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7 January 2021

Cytochrome P450 2E1 (CYP2E1) is essential for acrylonitrile metabolism to cyanide: comparative studies using CYP2E1-null and wild-type mice

1 reference

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Comparison of cancer risks projected from animal bioassays to epidemiologic studies of acrylonitrile-exposed workers

1 reference

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Formation of 8-oxodeoxyguanosine in brain DNA of rats exposed to acrylonitrile

1 reference

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Comparison of the dominant lethal effects of acrylonitrile and acrylamide in male Fischer 344 rats

1 reference

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Characterization of phosphodiester adducts produced by the reaction of cyanoethylene oxide with nucleotides.

1 reference

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Mechanisms for the induction of oxidative stress in Syrian hamster embryo cells by acrylonitrile

1 reference

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Acrylonitrile-induced morphological transformation in Syrian hamster embryo cells

1 reference

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Mortality of workers exposed to acrylonitrile

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/J.YRTPH.2005.06.007

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16099568

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

23 December 2017

http://europepmc.org/abstract/MED/16099568

ResearchGate publication ID

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