(Q46658255)

24 December 2017

title

A picrotoxin-specific conformational change in the glycine receptor M2-M3 loop (English)

1 reference

24 December 2017

author name string

Rebecca Hawthorne

series ordinal

1

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24 December 2017

Joseph W Lynch

series ordinal

2

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24 December 2017

language of work or name

English

0 references

publication date

18 August 2005

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24 December 2017

Journal of Biological Chemistry

published in

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24 December 2017

volume

280

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24 December 2017

issue

43

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24 December 2017

page(s)

35836-35843

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24 December 2017

The glycinergic inhibitory synapse.

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Structure and action of the nicotinic acetylcholine receptor explored by electron microscopy

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Mapping the conformational wave of acetylcholine receptor channel gating

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21 January 2018

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Mutations affecting the glycine receptor agonist transduction mechanism convert the competitive antagonist, picrotoxin, into an allosteric potentiator.

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A point mutation in a Drosophila GABA receptor confers insecticide resistance.

21 January 2018

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A single amino acid in gamma-aminobutyric acid rho 1 receptors affects competitive and noncompetitive components of picrotoxin inhibition

21 January 2018

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Cloning of a gamma-aminobutyric acid type C receptor subunit in rat retina with a methionine residue critical for picrotoxinin channel block

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Interaction of picrotoxin with GABAA receptor channel-lining residues probed in cysteine mutants.

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A single beta subunit M2 domain residue controls the picrotoxin sensitivity of alphabeta heteromeric glycine receptor chloride channels

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Picrotoxin accelerates relaxation of GABAC receptors

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Multiple mechanisms of picrotoxin block of GABA-induced currents in rat hippocampal neurons

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Identification of a novel residue within the second transmembrane domain that confers use-facilitated block by picrotoxin in glycine alpha 1 receptors.

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Openings of the rat recombinant alpha 1 homomeric glycine receptor as a function of the number of agonist molecules bound

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Trapping of organic blockers by closing of voltage-dependent K+ channels: evidence for a trap door mechanism of activation gating.

21 January 2018

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Ligand-induced closure of inward rectifier Kir6.2 channels traps spermine in the pore

21 January 2018

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Refined structure of the nicotinic acetylcholine receptor at 4A resolution

21 January 2018

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21 January 2018

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Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the alpha subunit.

21 January 2018

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The location of the gate in the acetylcholine receptor channel

21 January 2018

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Minimal structural rearrangement of the cytoplasmic pore during activation of the 5-HT3A receptor

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M506645200

1 reference

24 December 2017

1 reference

24 December 2017