(Q46677274)

24 December 2017

title

Population exposure-response modeling of metformin in patients with type 2 diabetes mellitus (English)

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24 December 2017

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Ying Hong

1

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24 December 2017

Shashank Rohatagi

2

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24 December 2017

Bahru Habtemariam

3

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24 December 2017

Joseph R Walker

4

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24 December 2017

Sherwyn L Schwartz

5

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24 December 2017

Donald E Mager

6

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24 December 2017

publication date

27 March 2008

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24 December 2017

The Journal of Clinical Pharmacology

published in

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24 December 2017

volume

48

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24 December 2017

issue

6

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24 December 2017

page(s)

696-707

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24 December 2017

cites work

Oral Antidiabetic Agents

1 reference

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Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

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Effect of metformin and rosiglitazone combination therapy in patients with type 2 diabetes mellitus: a randomized controlled trial.

21 January 2018

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Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus: progressive requirement for multiple therapies (UKPDS 49). UK Prospective Diabetes Study (UKPDS) Group.

21 January 2018

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Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus. The Multicenter Metformin Study Group.

21 January 2018

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21 January 2018

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21 January 2018

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Cardiovascular risk factors associated with insulin resistance: effects of oral antidiabetic agents

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21 January 2018

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Pharmacokinetic-pharmacodynamic modeling for the relationship between glucose-lowering effect and plasma concentration of metformin in volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270008316884

Pharmacokinetics and pharmacodynamics of metformin in healthy subjects and patients with noninsulin-dependent diabetes mellitus

21 January 2018

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Clinical pharmacokinetics of metformin

21 January 2018

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Metformin is a superior substrate for renal organic cation transporter OCT2 rather than hepatic OCT1.

21 January 2018

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Polymorphisms in a human kidney xenobiotic transporter, OCT2, exhibit altered function

21 January 2018

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A mechanism-based disease progression model for comparison of long-term effects of pioglitazone, metformin and gliclazide on disease processes underlying Type 2 Diabetes Mellitus.

21 January 2018

1 reference

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Population PKPD modelling of the long-term hypoglycaemic effect of gliclazide given as a once-a-day modified release (MR) formulation.

21 January 2018

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Modeling the metabolic effects of terbutaline in beta2-adrenergic receptor diplotypes.

21 January 2018

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Exendin-4 pharmacodynamics: insights from the hyperglycemic clamp technique

21 January 2018

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Pharmacodynamics of NN2211, a novel long acting GLP-1 derivative

21 January 2018

1 reference

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Metformin and lactic acidosis in diabetic humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270008316884

The relationship between metformin therapy and the fasting plasma lactate in type 2 diabetes: The Fremantle Diabetes Study

21 January 2018

1 reference

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Lactic acidemia associated with metformin

21 January 2018

1 reference

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Role of baseline parameters in determining indirect pharmacodynamic responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270008316884

21 January 2018

Identifiers

DOI

10.1177/0091270008316884

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24 December 2017

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24 December 2017