(Q46686084)

24 December 2017

title

Toxicity, DNA binding, and cell proliferation in male F344 rats following short-term gavage exposures to trans-2-hexenal (English)

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24 December 2017

author name string

Matthew D Stout

1

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24 December 2017

Elmarie Bodes

2

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24 December 2017

Robert Schoonhoven

3

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24 December 2017

Patricia B Upton

4

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24 December 2017

Gregory S Travlos

5

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24 December 2017

James A Swenberg

6

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24 December 2017

language of work or name

English

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publication date

1 February 2008

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24 December 2017

published in

Toxicologic Pathology

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24 December 2017

volume

36

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24 December 2017

issue

2

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24 December 2017

page(s)

232-246

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24 December 2017

Enzymes catalysing conjugations of glutathione with alpha-beta-unsaturated carbonyl compounds

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The reactive oxygen species--and Michael acceptor-inducible human aldo-keto reductase AKR1C1 reduces the alpha,beta-unsaturated aldehyde 4-hydroxy-2-nonenal to 1,4-dihydroxy-2-nonene

21 January 2018

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Mutation induction in Chinese hamster lung V79 cells by five alk-2-enals produced by lipid peroxidation

21 January 2018

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Forestomach tumor induction by 2,4-hexadienal in F344N rats and B6C3F1 mice.

21 January 2018

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Retrospective assessment of liver cell proliferation via PCNA: a comparison with tritiated thymidine

21 January 2018

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Genotoxic effects of the alpha, beta-unsaturated aldehydes 2-trans-butenal, 2-trans-hexenal and 2-trans, 6-cis-nonadienal

21 January 2018

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An HPLC-EC Assay for 1,N2-Propano Adducts of 2'-Deoxyguanosine with 4-Hydroxynonenal and Other .alpha.,.beta.-Unsaturated Aldehydes

21 January 2018

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A Multiple Comparison Procedure for Comparing Several Treatments with a Control

21 January 2018

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Mutagenicity of β-alkyl substituted acrolein congeners in theSalmonella typhimuriumstrain TA100 and genotoxicity testing in the SOS chromotest

21 January 2018

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Identification and characterization of deoxyguanosine adducts of mutagenic beta-alkyl-substituted acrolein congeners.

21 January 2018

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21 January 2018

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The influence of glutathione and detoxifying enzymes on DNA damage induced by 2-alkenals in primary rat hepatocytes and human lymphoblastoid cells

21 January 2018

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DNA-damaging potential and glutathione depletion of 2-cyclohexene-1-one in mammalian cells, compared to food relevant 2-alkenals.

21 January 2018

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(E)-2-hexenal-induced DNA damage and formation of cyclic 1,N2-(1,3-propano)-2'-deoxyguanosine adducts in mammalian cells

21 January 2018

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Genotoxicity and cytotoxicity of selected pyrrolizidine alkaloids, a possible alkenal metabolite of the alkaloids, and related alkenals.

21 January 2018

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Alpha,beta-unsaturated carbonyl compounds: induction of oxidative DNA damage in mammalian cells

21 January 2018

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21 January 2018

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The effects of exposure route on DNA adduct formation and cellular proliferation by 1,2,3-trichloropropane

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Cardiac toxic effects of trans-2-hexenal are mediated by induction of cardiomyocyte apoptotic pathways

21 January 2018

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Characterization of the glutathione binding site of aldose reductase

21 January 2018

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Detection of 1,N2-propanodeoxyguanosine adducts of 2-hexenal in organs of Fischer 344 rats by a 32P-post-labeling technique

21 January 2018

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A non-parametric equivalent of Williams' test for contrasting increasing dose levels of a treatment

21 January 2018

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Liquid chromatography-electrospray ionization-mass spectrometry: the future of DNA adduct detection

21 January 2018

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Selective protection by stably transfected human ALDH3A1 (but not human ALDH1A1) against toxicity of aliphatic aldehydes in V79 cells

21 January 2018

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Tumorigenicity of chloral hydrate, trichloroacetic acid, trichloroethanol, malondialdehyde, 4-hydroxy-2-nonenal, crotonaldehyde, and acrolein in the B6C3F(1) neonatal mouse

21 January 2018

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21 January 2018

Identifiers

DOI

10.1177/0192623307311758

1 reference

24 December 2017

1 reference

24 December 2017