(Q46690342)

24 December 2017

title

Polycystic kidneys caused by sustained expression of Cux1 isoform p75. (English)

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24 December 2017

author name string

Chantal Cadieux

1

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24 December 2017

Ryoko Harada

2

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24 December 2017

Marilène Paquet

3

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24 December 2017

Olivier Côté

4

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24 December 2017

Marie Trudel

5

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24 December 2017

Alain Nepveu

6

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24 December 2017

Maxime Bouchard

7

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24 December 2017

language of work or name

English

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publication date

20 March 2008

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24 December 2017

Journal of Biological Chemistry

published in

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24 December 2017

volume

283

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24 December 2017

issue

20

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24 December 2017

page(s)

13817-13824

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24 December 2017

The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains

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Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

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PKD1 interacts with PKD2 through a probable coiled-coil domain

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Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation

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21 January 2018

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A human PKD1 transgene generates functional polycystin-1 in mice and is associated with a cystic phenotype

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An activated allele of the c-erbB-2 oncogene impairs kidney and lung function and causes early death of transgenic mice

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Transgenic overexpression of prothymosin alpha induces development of polycystic kidney disease.

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Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

21 January 2018

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Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia

21 January 2018

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Role of the multifunctional CDP/Cut/Cux homeodomain transcription factor in regulating differentiation, cell growth and development

21 January 2018

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Drosophila melanogaster mutations suppressible by the suppressor of Hairy-wing are insertions of a 7.3-kilobase mobile element

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21 January 2018

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The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle

21 January 2018

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Lymphoid apoptosis and myeloid hyperplasia in CCAAT displacement protein mutant mice

21 January 2018

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Genetic ablation of the CDP/Cux protein C terminus results in hair cycle defects and reduced male fertility

21 January 2018

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Hair defects and pup loss in mice with targeted deletion of the first cut repeat domain of the Cux/CDP homeoprotein gene

21 January 2018

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CCAAT displacement activity involves CUT repeats 1 and 2, not the CUT homeodomain

21 January 2018

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S phase-specific proteolytic cleavage is required to activate stable DNA binding by the CDP/Cut homeodomain protein

21 January 2018

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A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor

21 January 2018

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21 January 2018

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Deregulated expression of the homeobox gene Cux-1 in transgenic mice results in downregulation of p27(kip1) expression during nephrogenesis, glomerular abnormalities, and multiorgan hyperplasia

21 January 2018

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Cux-1 transgenic mice develop glomerulosclerosis and interstitial fibrosis

21 January 2018

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Tumor cells exhibit deregulation of the cell cycle histone gene promoter factor HiNF-D.

21 January 2018

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Involvement of the cell cycle-regulated nuclear factor HiNF-D in cell growth control of a human H4 histone gene during hepatic development in transgenic mice

21 January 2018

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CDP/cut is the DNA-binding subunit of histone gene transcription factor HiNF-D: a mechanism for gene regulation at the G1/S phase cell cycle transition point independent of transcription factor E2F

21 January 2018

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The mammalian Cut homeodomain protein functions as a cell-cycle-dependent transcriptional repressor which downmodulates p21WAF1/CIP1/SDI1 in S phase

21 January 2018

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Increased expression and activity of nuclear cathepsin L in cancer cells suggests a novel mechanism of cell transformation.

21 January 2018

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The p110 isoform of the CDP/Cux transcription factor accelerates entry into S phase

21 January 2018

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Transgenic mice expressing the p75 CCAAT-displacement protein/Cut homeobox isoform develop a myeloproliferative disease-like myeloid leukemia

21 January 2018

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Trans-heterozygous Pkd1 and Pkd2 mutations modify expression of polycystic kidney disease.

21 January 2018

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Expression of a Delta homologue in prospective neurons in the chick

21 January 2018

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Genome-wide location analysis and expression studies reveal a role for p110 CUX1 in the activation of DNA replication genes

21 January 2018

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DNA-binding specificity of the cut repeats from the human cut-like protein

21 January 2018

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Tumor suppressor pRB functions as a co-repressor of the CCAAT displacement protein (CDP/cut) to regulate cell cycle controlled histone H4 transcription

21 January 2018

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21 January 2018

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21 January 2018

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CCAAT displacement protein/cut homolog recruits G9a histone lysine methyltransferase to repress transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709332200

The homeodomain protein CDP regulates mammary-specific gene transcription and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709332200

CDP/Cux stimulates transcription from the DNA polymerase alpha gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709332200

The human cut homeodomain protein represses transcription from the c-myc promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709332200

21 January 2018

Identifiers

DOI

10.1074/JBC.M709332200

1 reference

24 December 2017

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24 December 2017