(Q46698160)

24 December 2017

title

Human mismatch repair gene, MLH1, is transcriptionally repressed by the hypoxia-inducible transcription factors, DEC1 and DEC2. (English)

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24 December 2017

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H Nakamura

1

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24 December 2017

K Tanimoto

2

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24 December 2017

K Hiyama

3

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24 December 2017

M Yunokawa

4

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24 December 2017

T Kawamoto

5

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24 December 2017

Y Kato

6

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24 December 2017

K Yoshiga

7

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24 December 2017

L Poellinger

8

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24 December 2017

E Hiyama

9

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24 December 2017

M Nishiyama

10

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24 December 2017

language of work or name

English

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publication date

17 March 2008

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24 December 2017

published in

Oncogene

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24 December 2017

volume

27

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24 December 2017

issue

30

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24 December 2017

page(s)

4200-4209

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24 December 2017

https://scigraph.springernature.com/pub.10.1038/onc.2008.58

exact match

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cites work

Hypoxia-induced down-regulation of BRCA1 expression by E2Fs.

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https://api.crossref.org/works/10.1038%2FONC.2008.58

Co-repression of mismatch repair gene expression by hypoxia in cancer cells: role of the Myc/Max network

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Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cells

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Overcoming physiologic barriers to cancer treatment by molecularly targeting the tumor microenvironment

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Investigating hypoxic tumor physiology through gene expression patterns

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.58

Molecular cloning and characterization of DEC2, a new member of basic helix-loop-helix proteins

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.58

Hypoxia--a key regulatory factor in tumour growth

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https://api.crossref.org/works/10.1038%2FONC.2008.58

Genome maintenance mechanisms for preventing cancer

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.58

Dec1 and Dec2 are regulators of the mammalian molecular clock

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.58

Regulation of STRA13 by the von Hippel-Lindau tumor suppressor protein, hypoxia, and the UBC9/ubiquitin proteasome degradation pathway

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.58

Hypoxic repression of STAT1 and its downstream genes by a pVHL/HIF-1 target DEC1/STRA13.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.58

A novel autofeedback loop of Dec1 transcription involved in circadian rhythm regulation

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.58

HIF-1alpha induces genetic instability by transcriptionally downregulating MutSalpha expression.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.58

DEC1 negatively regulates the expression of DEC2 through binding to the E-box in the proximal promoter

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.58

Decreased Expression of the DNA Mismatch Repair Gene Mlh1 under Hypoxic Stress in Mammalian Cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.58

Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.58

Deficient DNA mismatch repair: a common etiologic factor for colon cancer

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.58

HIF-1 and hypoxic response: the plot thickens.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.58

Functional analysis of the basic helix-loop-helix transcription factor DEC1 in circadian regulation. Interaction with BMAL1

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.58

Targeting HIF-1 for cancer therapy

31 March 2020

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Molecular characterization of the novel basic helix-loop-helix protein DEC1 expressed in differentiated human embryo chondrocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.58

Stra13 expression is associated with growth arrest and represses transcription through histone deacetylase (HDAC)-dependent and HDAC-independent mechanisms

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.58

Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.58

Hypoxia-inducible factor-1alpha polymorphisms associated with enhanced transactivation capacity, implying clinical significance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.58

Hypoxia and drug resistance

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.58

Inhibition of PPAR gamma 2 gene expression by the HIF-1-regulated gene DEC1/Stra13: a mechanism for regulation of adipogenesis by hypoxia

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.58

31 March 2020

Identifiers

DOI

10.1038/ONC.2008.58

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24 December 2017

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24 December 2017