(Q46709691)

24 December 2017

title

Modulation of amyloid-beta aggregation and toxicity by inosose stereoisomers (English)

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24 December 2017

author name string

Mark Nitz

1

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24 December 2017

Daniela Fenili

2

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24 December 2017

Audrey A Darabie

3

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24 December 2017

Ling Wu

4

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24 December 2017

Julian E Cousins

5

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24 December 2017

JoAnne McLaurin

6

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24 December 2017

language of work or name

English

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publication date

5 March 2008

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24 December 2017

published in

FEBS Journal

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24 December 2017

volume

275

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24 December 2017

issue

8

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24 December 2017

page(s)

1663-1674

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24 December 2017

Inositol and higher inositol phosphates in neural tissues: homeostasis, metabolism and functional significance

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Properties of scyllo-inositol as a therapeutic treatment of AD-like pathology.

21 January 2018

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Inositol stereoisomers stabilize an oligomeric aggregate of Alzheimer amyloid beta peptide and inhibit abeta -induced toxicity.

21 January 2018

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Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.

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Orally available compound prevents deficits in memory caused by the Alzheimer amyloid-beta oligomers.

21 January 2018

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Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct

21 January 2018

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Structure of beta-amyloid fibrils and its relevance to their neurotoxicity: implications for the pathogenesis of Alzheimer's disease.

21 January 2018

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Myo-inositol transport through the blood-brain barrier.

21 January 2018

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myo-inositol transport in mouse astroglia-rich primary cultures.

21 January 2018

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Identification of a mammalian H(+)-myo-inositol symporter expressed predominantly in the brain

21 January 2018

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Identification of a novel Na+/myo-inositol cotransporter

21 January 2018

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Kinetics and specificity of the renal Na+/myo-inositol cotransporter expressed in Xenopus oocytes

21 January 2018

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Free and lipid myo-inositol in tissues from rats with acute and less severe streptozotocin-induced diabetes

21 January 2018

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Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

21 January 2018

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Inhibition of amyloid fibril formation by polyphenols: structural similarity and aromatic interactions as a common inhibition mechanism

21 January 2018

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Amyloid-beta interactions with chondroitin sulfate-derived monosaccharides and disaccharides. implications for drug development

21 January 2018

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21 January 2018

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Screening for inhibitors of tau polymerization

21 January 2018

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Common structural features determine the effectiveness of carvedilol, daunomycin and rolitetracycline as inhibitors of Alzheimer beta-amyloid fibril formation

21 January 2018

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New Class of Inhibitors of Amyloid-beta Fibril Formation. IMPLICATIONS FOR THE MECHANISM OF PATHOGENESIS IN ALZHEIMER'S DISEASE

21 January 2018

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Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity

21 January 2018

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The transport and metabolism of scyllo-inositol in the central nervous system

21 January 2018

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10.1111/J.1742-4658.2008.06321.X

21 January 2018

Identifiers

DOI

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24 December 2017

1 reference

24 December 2017