(Q46715836)

24 December 2017

title

An ESI-MS method for characterization of native and modified oligonucleotides used for RNA interference and other biological applications (English)

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24 December 2017

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Samit Shah

1

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24 December 2017

Simon H Friedman

series ordinal

2

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24 December 2017

publication date

1 January 2008

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24 December 2017

published in

Nature Protocols

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24 December 2017

volume

3

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24 December 2017

issue

3

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24 December 2017

page(s)

351-356

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24 December 2017

RNA interference is mediated by 21- and 22-nucleotide RNAs

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2007.535

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RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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A large-scale RNAi screen in human cells identifies new components of the p53 pathway

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A resource for large-scale RNA-interference-based screens in mammals.

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RNAi in human cells: basic structural and functional features of small interfering RNA.

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Chemical modification of siRNAs to improve serum stability without loss of efficacy.

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Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells

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Improving RNA interference in mammalian cells by 4'-thio-modified small interfering RNA (siRNA): effect on siRNA activity and nuclease stability when used in combination with 2'-O-alkyl modifications.

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Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality

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Inhibition of MDR1 expression with altritol-modified siRNAs

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Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing

31 March 2020

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RNA interference induced by siRNAs modified with 4'-thioribonucleosides in cultured mammalian cells

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Hypoxia reduces constitutive and TNF-alpha-induced expression of monocyte chemoattractant protein-1 in human proximal renal tubular cells.

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Steroid and lipid conjugates of siRNAs to enhance cellular uptake and gene silencing in liver cells

31 March 2020

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RNA interference and chemically modified small interfering RNAs

31 March 2020

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Lung delivery studies using siRNA conjugated to TAT(48-60) and penetratin reveal peptide induced reduction in gene expression and induction of innate immunity.

31 March 2020

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Tolerance of RNA interference toward modifications of the 5' antisense phosphate of small interfering RNA.

31 March 2020

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Light-activated RNA interference

31 March 2020

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Molecular mass measurement of intact ribonucleic acids via electrospray ionization quadrupole mass spectrometry

31 March 2020

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https://api.crossref.org/works/10.1038%2FNPROT.2007.535

Negative electrospray ionization mass spectrometry of synthetic and chemically modified oligonucleotides

31 March 2020

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https://api.crossref.org/works/10.1038%2FNPROT.2007.535

31 March 2020

Identifiers

DOI

10.1038/NPROT.2007.535

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24 December 2017

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24 December 2017