(Q46719817)

24 December 2017

title

Tyrosine-phosphorylated Hic-5 inhibits epidermal growth factor-induced lamellipodia formation (English)

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24 December 2017

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Sara E Hetey

1

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24 December 2017

David P Lalonde

series ordinal

2

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24 December 2017

Christopher E Turner

series ordinal

3

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24 December 2017

language of work or name

English

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publication date

22 September 2005

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24 December 2017

Experimental Cell Research

published in

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24 December 2017

volume

311

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24 December 2017

issue

1

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24 December 2017

page(s)

147-156

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24 December 2017

Cloning from a mouse osteoblastic cell line of a set of transforming-growth-factor-beta 1-regulated genes, one of which seems to encode a follistatin-related polypeptide

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Interaction of Hic-5, A senescence-related protein, with focal adhesion kinase

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The paxillin LD motifs

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The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling

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Hic-5-reduced cell spreading on fibronectin: competitive effects between paxillin and Hic-5 through interaction with focal adhesion kinase

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Phosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells

7 January 2021

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Crk associates with a multimolecular Paxillin/GIT2/beta-PIX complex and promotes Rac-dependent relocalization of Paxillin to focal contacts

7 January 2021

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Epidermal growth factor stimulates serine/threonine phosphorylation of the focal adhesion protein paxillin in a MEK-dependent manner in normal rat kidney cells

7 January 2021

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Dissociation of focal adhesion kinase and paxillin tyrosine phosphorylation induced by bombesin and lysophosphatidic acid from epidermal growth factor receptor transactivation in Swiss 3T3 cells

7 January 2021

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Roles of Gab1 and SHP2 in paxillin tyrosine dephosphorylation and Src activation in response to epidermal growth factor

7 January 2021

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Cell adhesion kinase beta forms a complex with a new member, Hic-5, of proteins localized at focal adhesions

7 January 2021

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Phosphorylation of Hic-5 at tyrosine 60 by CAKbeta and Fyn.

7 January 2021

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Cloning and characterization of androgen receptor coactivator, ARA55, in human prostate

7 January 2021

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Suppression of androgen receptor transactivation by Pyk2 via interaction and phosphorylation of the ARA55 coregulator

7 January 2021

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Positional Control of Cell Fate Through Joint Integrin/Receptor Protein Kinase Signaling

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The lamellipodium: where motility begins

7 January 2021

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

7 January 2021

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Role of actin polymerization and adhesion to extracellular matrix in Rac- and Rho-induced cytoskeletal reorganization

7 January 2021

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Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling

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The integrin-linked kinase regulates cell morphology and motility in a rho-associated kinase-dependent manner

7 January 2021

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The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin

7 January 2021

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Coactivation of Rac1 and Cdc42 at lamellipodia and membrane ruffles induced by epidermal growth factor.

7 January 2021

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Actopaxin interacts with TESK1 to regulate cell spreading on fibronectin

7 January 2021

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Mechanism of epidermal growth factor regulation of Vav2, a guanine nucleotide exchange factor for Rac

7 January 2021

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An activating mutant of Rac1 that fails to interact with Rho GDP-dissociation inhibitor stimulates membrane ruffling in mammalian cells

7 January 2021

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Hic-5, a paxillin homologue, binds to the protein-tyrosine phosphatase PEST (PTP-PEST) through its LIM 3 domain

7 January 2021

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The LD4 motif of paxillin regulates cell spreading and motility through an interaction with paxillin kinase linker (PKL).

7 January 2021

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Rho and Rac take center stage

7 January 2021

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7 January 2021

Lamellipodia in invasion

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Pyk2 and FAK regulate neurite outgrowth induced by growth factors and integrins

7 January 2021

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FAK integrates growth-factor and integrin signals to promote cell migration

7 January 2021

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Cellular functions regulated by Src family kinases

7 January 2021

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Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas) complex

7 January 2021

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Protein tyrosine kinases Src and Csk: a tail's tale

7 January 2021

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Src phosphorylation of the epidermal growth factor receptor at novel sites mediates receptor interaction with Src and P85 alpha

7 January 2021

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Review of epidermal growth factor receptor biology

7 January 2021

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The role of the epidermal growth factor receptor family in mammary tumorigenesis and metastasis

7 January 2021

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Specific decrease in the level of Hic-5, a focal adhesion protein, during immortalization of mouse embryonic fibroblasts, and its association with focal adhesion kinase

7 January 2021

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Induction of senescence-like phenotypes by forced expression of hic-5, which encodes a novel LIM motif protein, in immortalized human fibroblasts

7 January 2021

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Tumor progression: Small GTPases and loss of cell-cell adhesion

7 January 2021

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10.1016/J.YEXCR.2005.08.011

7 January 2021

Identifiers

DOI

1 reference

24 December 2017

1 reference

24 December 2017