(Q46750743)

English

Enantiomeric 1,2,4-trioxanes display equivalent in vitro antimalarial activity versus Plasmodium falciparum malaria parasites: implications for the molecular mechanism of action of the artemisinins

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16222725

Enantiomeric 1,2,4-trioxanes display equivalent in vitro antimalarial activity versus Plasmodium falciparum malaria parasites: implications for the molecular mechanism of action of the artemisinins (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16222725

Plasmodium falciparum

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1 reference

based on heuristic

inferred from title

Plasmodium falciparum malaria

1 reference

based on heuristic

inferred from title

author name string

Paul M O'Neill

1

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16222725

Sarah L Rawe

2

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16222725

Kristina Borstnik

3

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16222725

Alison Miller

4

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16222725

Stephen A Ward

5

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16222725

Patrick G Bray

6

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16222725

Jill Davies

7

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16222725

Chang Ho Oh

8

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16222725

Gary H Posner

9

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16222725

publication date

1 November 2005

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16222725

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16222725

6

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16222725

11

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16222725

2048-2054

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16222725

Knowledge of the proposed chemical mechanism of action and cytochrome p450 metabolism of antimalarial trioxanes like artemisinin allows rational design of new antimalarial peroxides

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500048

21 January 2018

A medicinal chemistry perspective on artemisinin and related endoperoxides

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500048

21 January 2018

Possible modes of action of the artemisinin-type compounds.

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500048

21 January 2018

Radical mechanism of action of the artemisinin-type compounds

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500048

21 January 2018

The mode of action of antimalarial endoperoxides

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500048

21 January 2018

The Plasmodium falciparum translationally controlled tumor protein homolog and its reaction with the antimalarial drug artemisinin

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500048

21 January 2018

How might qinghaosu (artemisinin) and related compounds kill the intraerythrocytic malaria parasite? A chemist's view

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500048

21 January 2018

Artemisinins target the SERCA of Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500048

21 January 2018

Artemisinins: mechanisms of action and potential for resistance

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500048

21 January 2018

Artemisinin Antimalarials Do Not Inhibit Hemozoin Formation

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500048

21 January 2018

Artemisinins: activities and actions

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500048

21 January 2018

Artemisinin and derivatives: the future for malaria treatment?

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500048

21 January 2018

Orally active antimalarial 3-substituted trioxanes: new synthetic methodology and biological evaluation.

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500048

21 January 2018

Antimalarial simplified 3-aryltrioxanes: synthesis and preclinical efficacy/toxicity testing in rodents.

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500048

21 January 2018

Orally active, water-soluble antimalarial 3-aryltrioxanes: short synthesis and preclinical efficacy testing in rodents

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500048

21 January 2018

Activity of benflumetol and its enantiomers in fresh isolates of Plasmodium falciparum from East Africa

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500048

21 January 2018

In vitro activity of the enantiomers of mefloquine, halofantrine and enpiroline against Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500048

21 January 2018

Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200500048

21 January 2018

Identifiers

10.1002/CBIC.200500048

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16222725

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16222725

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