(Q46755359)

24 December 2017

http://europepmc.org/abstract/MED/25798843

title

A novel cysteine cathepsin inhibitor yields macrophage cell death and mammary tumor regression (English)

1 reference

24 December 2017

http://europepmc.org/abstract/MED/25798843

0 references

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25798843%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

S J Salpeter

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25798843%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Y Pozniak

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25798843%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

E Merquiol

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25798843%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

T Geiger

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25798843%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

G Blum

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25798843%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

language of work or name

English

0 references

publication date

23 March 2015

1 reference

24 December 2017

http://europepmc.org/abstract/MED/25798843

published in

Oncogene

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25798843%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25798843%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

issue

50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25798843%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

6066-6078

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25798843%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/onc.2015.51

7 June 2020

exact match

0 references

cites work

Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis

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https://api.crossref.org/works/10.1038%2FONC.2015.51

Macrophage diversity enhances tumor progression and metastasis

21 January 2018

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Tumor associated macrophages and neutrophils in tumor progression

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Macrophage plasticity and polarization in tissue repair and remodelling

21 January 2018

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Trophic macrophages in development and disease

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Inflammation, wound repair, and fibrosis: reassessing the spectrum of tissue injury and resolution

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Macrophage plasticity and polarization: in vivo veritas

21 January 2018

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Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2015.51

Cysteine cathepsins in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.51

Immunolocalization of cathepsin B in human glioma: implications for tumor invasion and angiogenesis

21 January 2018

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Cysteine cathepsin proteases as pharmacological targets in cancer

21 January 2018

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IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion

21 January 2018

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Increased expression and activity of nuclear cathepsin L in cancer cells suggests a novel mechanism of cell transformation.

21 January 2018

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A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.51

Inhibition of cysteine protease activity disturbs DNA replication and prevents mitosis in the early mitotic cell cycles of sea urchin embryos

21 January 2018

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Induction of autophagy is essential for monocyte-macrophage differentiation

21 January 2018

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Cysteine proteases: destruction ability versus immunomodulation capacity in immune cells.

21 January 2018

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The p50 subunit of NF-κB orchestrates dendritic cell lifespan and activation of adaptive immunity

21 January 2018

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Role of c-MYC in tumor-associated macrophages and cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.51

Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.51

Trial of the cysteine cathepsin inhibitor JPM-OEt on early and advanced mammary cancer stages in the MMTV-PyMT-transgenic mouse model.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2015.51

Dynamic imaging of protease activity with fluorescently quenched activity-based probes.

21 January 2018

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Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB.

21 January 2018

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Cathepsin L mediates resveratrol-induced autophagy and apoptotic cell death in cervical cancer cells

21 January 2018

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Impaired turnover of autophagolysosomes in cathepsin L deficiency

21 January 2018

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A novel proteolytically processed CDP/Cux isoform of 90 kDa is generated by cathepsin L.

21 January 2018

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Posttranslational processing and modification of cathepsins and cystatins

21 January 2018

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Cathepsin S deficiency results in abnormal accumulation of autophagosomes in macrophages and enhances Ang II-induced cardiac inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.51

Macrophage autophagy plays a protective role in advanced atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.51

Acute oxidative stress is associated with cell proliferation in the mouse liver

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2015.51

Autophagy is required for CSF-1-induced macrophagic differentiation and acquisition of phagocytic functions.

21 January 2018

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Targeting proteases: successes, failures and future prospects

21 January 2018

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Cathepsin B inhibition limits bone metastasis in breast cancer

21 January 2018

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Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model.

21 January 2018

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Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer

21 January 2018

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Selective ablation of tumor-associated macrophages suppresses metastasis and angiogenesis

21 January 2018

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Universal sample preparation method for proteome analysis

21 January 2018

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Combination of FASP and StageTip-based fractionation allows in-depth analysis of the hippocampal membrane proteome

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2015.51

Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.51

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.51

Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.51

Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.51

Inhibition of cysteine cathepsin protease activity enhances chemotherapy regimens by decreasing tumor growth and invasiveness in a mouse model of multistage cancer

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2015.51

Mechanistic studies on the inactivation of papain by epoxysuccinyl inhibitors

31 March 2020

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Interleukin-4 inhibits mitogen-induced proliferation of human airway smooth muscle cells in culture

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25798843

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Emerging roles of cysteine cathepsins in disease and their potential as drug targets.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25798843