(Q46755440)

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Two-photon imaging of stroke onset in vivo reveals that NMDA-receptor independent ischemic depolarization is the major cause of rapid reversible damage to dendrites and spines

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Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18272696

Two-photon imaging of stroke onset in vivo reveals that NMDA-receptor independent ischemic depolarization is the major cause of rapid reversible damage to dendrites and spines (English)

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18272696

author name string

Timothy H Murphy

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671530&resulttype=core&format=json

16 May 2020

Ping Li

2

1 reference

Europe PubMed Central

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16 May 2020

Kellen Betts

3

1 reference

Europe PubMed Central

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16 May 2020

Richard Liu

4

1 reference

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16 May 2020

language of work or name

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publication date

1 February 2008

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18272696

Journal of Neuroscience

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Europe PubMed Central

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16 May 2020

28

1 reference

Europe PubMed Central

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16 May 2020

1756-1772

1 reference

Europe PubMed Central

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16 May 2020

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671530&resulttype=core&format=json

16 May 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6671530/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

The effect of rapid preconditioning on the microglial, astrocytic and neuronal consequences of global cerebral ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential sources of intrinsic optical signals imaged in live brain slices.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The changing landscape of ischaemic brain injury mechanisms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Imaging cortical dynamics at high spatial and temporal resolution with novel blue voltage-sensitive dyes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Threshold of ischemic depolarization for neuronal injury following four-vessel occlusion in the rat cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High speed diffusion magnetic resonance imaging of ischemia and spontaneous periinfarct spreading depression after thromboembolic stroke in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Imaging anoxic depolarization during ischemia-like conditions in the mouse hemi-brain slice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anoxic depolarization mediates acute damage independent of glutamate in neocortical brain slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendritic spines lost during glutamate receptor activation reemerge at original sites of synaptic contact.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reducing the environmental sensitivity of yellow fluorescent protein. Mechanism and applications

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein aggregation after focal brain ischemia and reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A serial MR study of cerebral blood flow changes and lesion development following endothelin-1-induced ischemia in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid and reversible changes in dendrite morphology and synaptic efficacy following NMDA receptor activation: implication for a cellular defense against excitotoxicity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spreading and synchronous depressions of cortical activity in acutely injured human brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Animal models of focal and global cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo two-photon calcium imaging of neuronal networks

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coupling of total hemoglobin concentration, oxygenation, and neural activity in rat somatosensory cortex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain damage in a mouse model of global cerebral ischemia. Effect of NMDA receptor blockade

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ion homeostasis in rat brain in vivo: intra- and extracellular [Ca2+] and [H+] in the hippocampus during recovery from short-term, transient ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection against ischemic hippocampal CA1 damage in the rat with a new non-NMDA antagonist, NBQX

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A key role for TRPM7 channels in anoxic neuronal death

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A model of global cerebral ischemia in C57 BL/6 mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electron microscopic investigation of the cerebral cortex after cerebral ischemia and reperfusion in the gerbil

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The rise and fall of NMDA antagonists for ischemic stroke.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repeated negative DC deflections in rat cortex following middle cerebral artery occlusion are abolished by MK-801: effect on volume of ischemic injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendritic spines disappear with chilling but proliferate excessively upon rewarming of mature hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determinants of cardiac electrophysiological properties in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blocking the anoxic depolarization protects without functional compromise following simulated stroke in cortical brain slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

VSDI: a new era in functional imaging of cortical dynamics

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fixing the heart: must the brain pay the price?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of connexin-based gap junction channels and hemichannels in ischemia-induced cell death in nervous tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuritic beading induced by activated microglia is an early feature of neuronal dysfunction toward neuronal death by inhibition of mitochondrial respiration and axonal transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional imaging with cellular resolution reveals precise micro-architecture in visual cortex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal death/survival signaling pathways in cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous detection of blood volume, oxygenation, and intracellular calcium changes during cerebral ischemia and reperfusion in vivo using diffuse reflectance and fluorescence

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spatial extent of oxygen metabolism and hemodynamic changes during functional activation of the rat somatosensory cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid reversible changes in dendritic spine structure in vivo gated by the degree of ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of AMPA receptor antagonists in models of stroke and neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Imaging input and output of neocortical networks in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular dementia prevention: a risk factor analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vasoconstrictive neurovascular coupling during focal ischemic depolarizations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two-photon imaging of cortical surface microvessels reveals a robust redistribution in blood flow after vascular occlusion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted insult to subsurface cortical blood vessels using ultrashort laser pulses: three models of stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two-photon imaging of glutathione levels in intact brain indicates enhanced redox buffering in developing neurons and cells at the cerebrospinal fluid and blood-brain interface.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of the AMPA receptor prevents CA1 hippocampal injury following severe but transient forebrain ischemia in adult rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ischemia opens neuronal gap junction hemichannels.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocytic Ca2+ signaling evoked by sensory stimulation in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Visualizing the cortical representation of whisker touch: voltage-sensitive dye imaging in freely moving mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathophysiology and therapy of experimental stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebral preconditioning and ischaemic tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological evidence that pyramidal neurons lack functional water channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Origin sites of spontaneous cortical spreading depression migrated during focal cerebral ischemia in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamic changes in CA1 dendritic spines associated with ischemic tolerance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acidotoxicity trumps excitotoxicity in ischemic brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensory-evoked intrinsic optical signals in the olfactory bulb are coupled to glutamate release and uptake.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium-triggered exit of F-actin and IP(3) 3-kinase A from dendritic spines is rapid and reversible.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium-dependent NMDA-induced dendritic injury and MAP2 loss in acute hippocampal slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preconditioning reprograms the response to ischemic injury and primes the emergence of unique endogenous neuroprotective phenotypes: a speculative synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct vascular conduction with cortical spreading depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-resolution in vivo imaging of the neurovascular unit during spreading depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extensive turnover of dendritic spines and vascular remodeling in cortical tissues recovering from stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Imaging the impact of cortical microcirculation on synaptic structure and sensory-evoked hemodynamic responses in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cortical spreading depression causes and coincides with tissue hypoxia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid astrocyte calcium signals correlate with neuronal activity and onset of the hemodynamic response in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial Dysfunction and Dendritic Beading during Neuronal Toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kainate seizures cause acute dendritic injury and actin depolymerization in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MK-801 reduced cerebral ischemic injury by inducing hypothermia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular and extracellular changes of [Ca2+] in hypoxia and ischemia in rat brain in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific permeability and selective formation of gap junction channels in connexin-transfected HeLa cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ion channel involvement in anoxic depolarization induced by cardiac arrest in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMPA, but not NMDA, receptor antagonism is neuroprotective in gerbil global ischaemia, even when delayed 24 h.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BW1003C87 and NBQX but not CGS19755 reduce glutamate release and cerebral ischemic necrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional and morphological changes induced by transient in vivo ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lidocaine delays cortical ischemic depolarization: relationship to electrophysiologic recovery and neuropathology.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of cortical depolarizations evoked in focal cerebral ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optical imaging of the functional architecture in cat visual cortex: the layout of direction and orientation domains.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotection after several days of mild, drug-induced hypothermia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Periinfarct depolarizations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adverse cerebral outcomes after coronary bypass surgery. Multicenter Study of Perioperative Ischemia Research Group and the Ischemia Research and Education Foundation Investigators.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid alterations in dendrite morphology during sublethal hypoxia or glutamate receptor activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C57BL/6 strain is most susceptible to cerebral ischemia following bilateral common carotid occlusion among seven mouse strains: selective neuronal death in the murine transient forebrain ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium in ischemic cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anoxic depolarization determines ischemic brain injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged enhancement and depression of synaptic transmission in CA1 pyramidal neurons induced by transient forebrain ischemia in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluctuations and stimulus-induced changes in blood flow observed in individual capillaries in layers 2 through 4 of rat neocortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct roles for sodium, chloride, and calcium in excitotoxic dendritic injury and recovery.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18272696

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.5128-07.2008

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671530&resulttype=core&format=json

16 May 2020

release_3qwdnxddarhdpg5tdjvf5ppcza

1 reference

https://api.fatcat.wiki/v0/release/3qwdnxddarhdpg5tdjvf5ppcza

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671530&resulttype=core&format=json

16 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671530&resulttype=core&format=json

16 May 2020

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