(Q46761763)

25 December 2017

title

Autoreactivity and allelic inclusion in a B cell nuclear transfer mouse (English)

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25 December 2017

author name string

Tobias Gerdes

series ordinal

1

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25 December 2017

Matthias Wabl

series ordinal

2

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25 December 2017

language of work or name

English

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publication date

31 October 2004

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25 December 2017

published in

Nature Immunology

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25 December 2017

volume

5

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25 December 2017

issue

12

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25 December 2017

page(s)

1282-1287

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25 December 2017

Cellular localization of immunoglobulins with different allotypic specificities in rabbit lymphoid tissues

cites work

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Differential activity of allelic gamma-globulin genes in antibody-producing cells

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Frequency and characterization of phenotypic Ig heavy chain allelically included IgM-expressing B cells in mice.

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Receptor editing: an approach by autoreactive B cells to escape tolerance

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Receptor editing in self-reactive bone marrow B cells

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Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification

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Receptor editing is the main mechanism of B cell tolerance toward membrane antigens

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Antigen receptor 'capacity' and the sensitivity of self-tolerance.

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Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.

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Receptor editing occurs frequently during normal B cell development.

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Predominant autoantibody production by early human B cell precursors

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Analysis of B cell receptor production and rearrangement. Part I. Light chain rearrangement.

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Multiple immunoglobulin heavy-chain gene transcripts in Abelson murine leukemia virus-transformed lymphoid cell lines

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A theory of allelic and isotypic exclusion for immunoglobulin genes

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Haplotype exclusion and receptor editing: irreconcilable differences?

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Natural autoantibodies.

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Second generation immune networks

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Allelic inclusion of T cell receptor alpha genes poses an autoimmune hazard due to low-level expression of autospecific receptors

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Monoclonal mice generated by nuclear transfer from mature B and T donor cells

21 January 2018

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Role of receptor editing and revision in shaping the B and T lymphocyte repertoire.

21 January 2018

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Double light chain producing lymphocytes: an enigma of allelic exclusion

21 January 2018

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Regulation of anti-DNA B cells in recombination-activating gene-deficient mice

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Frequent lambda light chain gene rearrangement and expression in a Ly-1 B lymphoma with a productive kappa chain allele

21 January 2018

1 reference

Two kappa immunoglobulin genes are expressed in the myeloma S107.

21 January 2018

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Differential accessibility at the kappa chain locus plays a role in allelic exclusion

21 January 2018

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Variegated transcriptional activation of the immunoglobulin kappa locus in pre-b cells contributes to the allelic exclusion of light-chain expression

21 January 2018

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Lymphocytes of the ToadXenopus laevisHave the Gene Set for Promoting Tadpole Development

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Contribution of Receptor Editing to the Antibody Repertoire

21 January 2018

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Self-reactive antibodies (natural autoantibodies) in healthy individuals

21 January 2018

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Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

21 January 2018

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Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression

21 January 2018

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Allelic exclusion and control of endogenous immunoglobulin gene rearrangement in κ transgenic mice

21 January 2018

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Editing disease-associated autoantibodies

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7 January 2021

Positive selection of natural autoreactive B cells

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7 January 2021

Natural autoantibodies

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7 January 2021

Frequencies of multiple IgL chain gene rearrangements in single normal or kappaL chain-deficient B lineage cells

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7 January 2021

Evidence for selection of a population of multi-reactive B cells into the splenic marginal zone

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7 January 2021

Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice

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7 January 2021

Double producers of kappa and lambda define a subset of B cells in mouse plasmacytomas

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7 January 2021

Identifiers

DOI

10.1038/NI1133

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25 December 2017

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25 December 2017