(Q46767741)

English

The clustering of GABA(A) receptor subtypes at inhibitory synapses is facilitated via the direct binding of receptor alpha 2 subunits to gephyrin.

scientific article published in February 2008

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scholarly article

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2 January 2020

The clustering of GABA(A) receptor subtypes at inhibitory synapses is facilitated via the direct binding of receptor alpha 2 subunits to gephyrin (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18256255%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Jean-Marc Fritschy

4

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2 January 2020

author name string

Verena Tretter

1

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2 January 2020

Tija C Jacob

2

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2 January 2020

Jayanta Mukherjee

3

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2 January 2020

Menelas N Pangalos

5

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2 January 2020

Stephen J Moss

6

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2 January 2020

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publication date

1 February 2008

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2 January 2020

Journal of Neuroscience

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2 January 2020

28

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2 January 2020

1356-1365

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2 January 2020

6

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2 January 2020

Hydrophobic interactions mediate binding of the glycine receptor beta-subunit to gephyrin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Postsynaptic clustering of major GABAA receptor subtypes requires the gamma 2 subunit and gephyrin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of postsynaptic GABA(A) receptor clustering in gephyrin-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of residues within GABA(A) receptor alpha subunits that mediate specific assembly with receptor beta subunits.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Receptors, gephyrin and gephyrin-associated proteins: novel insights into the assembly of inhibitory postsynaptic membrane specializations

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mini-review: gephyrin, a major postsynaptic protein of GABAergic synapses

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive endocytosis of GABAA receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of GABAA receptor assembly in mammalian cell lines and hippocampal neurons using gamma 2 subunit green fluorescent protein chimeras.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GABA(A) receptors: immunocytochemical distribution of 13 subunits in the adult rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Input-dependent synaptic targeting of alpha(2)-subunit-containing GABA(A) receptors in synapses of hippocampal pyramidal cells of the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gephyrin-independent clustering of postsynaptic GABA(A) receptor subtypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GABA(A) receptor cell surface number and subunit stability are regulated by the ubiquitin-like protein Plic-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subunit composition, distribution and function of GABA(A) receptor subtypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ectopic expression of the GABA(A) receptor alpha6 subunit in hippocampal pyramidal neurons produces extrasynaptic receptors and an increased tonic inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of GABAA receptor assembly and trafficking: implications for the modulation of inhibitory neurotransmission.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of GABAA receptor activity by phosphorylation and receptor trafficking: implications for the efficacy of synaptic inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gephyrin is critical for glycine receptor clustering but not for the formation of functional GABAergic synapses in hippocampal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Marlin-1, a novel RNA-binding protein associates with GABA receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of GABAA receptor trafficking, channel activity, and functional plasticity of inhibitory synapses.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Huntingtin-associated protein 1 regulates inhibitory synaptic transmission by modulating gamma-aminobutyric acid type A receptor membrane trafficking

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct gamma2 subunit domains mediate clustering and synaptic function of postsynaptic GABAA receptors and gephyrin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clustered and non-clustered GABAA receptors in cultured hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phospho-dependent binding of the clathrin AP2 adaptor complex to GABAA receptors regulates the efficacy of inhibitory synaptic transmission

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gephyrin regulates the cell surface dynamics of synaptic GABAA receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How to build a central synapse: clues from cell culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GABA-based therapeutic approaches: GABAA receptor subtype functions

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic GABAA receptors are directly recruited from their extrasynaptic counterparts

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

From synapse to behavior: rapid modulation of defined neuronal types with engineered GABAA receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Colocalization of gephyrin and GABAA-receptor subunits in the rat retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assembly and cell surface expression of heteromeric and homomeric gamma-aminobutyric acid type A receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GABAA-receptor heterogeneity in the adult rat brain: differential regional and cellular distribution of seven major subunits

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting of glycine receptor subunits to gephyrin-rich domains in transfected human embryonic kidney cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subcellular localization of gamma-aminobutyric acid type A receptors is determined by receptor beta subunits

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential synaptic localization of two major gamma-aminobutyric acid type A receptor alpha subunits on hippocampal pyramidal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/18256255

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.5050-07.2008

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18256255%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18256255%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18256255%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

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