(Q46781268)

25 December 2017

title

Non-steroidal aromatase inhibitors based on a biphenyl scaffold: synthesis, in vitro SAR, and molecular modelling (English)

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25 December 2017

author name string

Toby Jackson

1

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25 December 2017

L W Lawrence Woo

2

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25 December 2017

Melanie N Trusselle

3

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25 December 2017

Atul Purohit

4

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25 December 2017

Michael J Reed

5

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25 December 2017

Barry V L Potter

6

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25 December 2017

publication date

1 April 2008

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25 December 2017

published in

ChemMedChem

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25 December 2017

volume

3

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25 December 2017

issue

4

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25 December 2017

page(s)

603-618

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25 December 2017

Nonsteroidal aromatase inhibitors: recent advances

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700266

7 January 2021

Aromatase inhibitors in the treatment of breast cancer.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700266

7 January 2021

A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700266

7 January 2021

Switching of postmenopausal women with endocrine-responsive early breast cancer to anastrozole after 2 years' adjuvant tamoxifen: combined results of ABCSG trial 8 and ARNO 95 trial

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700266

7 January 2021

Aromatase inhibitors: synthesis, biological activity, and binding mode of azole-type compounds

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700266

7 January 2021

A molecular model for the interaction between vorozole and other non-steroidal inhibitors and human cytochrome P450 19 (P450 aromatase)

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700266

7 January 2021

A new class of nonsteroidal aromatase inhibitors: design and synthesis of chromone and xanthone derivatives and inhibition of the P450 enzymes aromatase and 17 alpha-hydroxylase/C17,20-lyase

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700266

7 January 2021

Looking for selectivity among cytochrome P450s inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700266

7 January 2021

Potent CYP19 (aromatase) 1-[(benzofuran-2-yl)(phenylmethyl)pyridine, -imidazole, and -triazole inhibitors: synthesis and biological evaluation.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700266

7 January 2021

Lead optimization providing a series of flavone derivatives as potent nonsteroidal inhibitors of the cytochrome P450 aromatase enzyme

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700266

7 January 2021

Imidazolylmethylbenzophenones as highly potent aromatase inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700266

7 January 2021

Synthesis and Biological Evaluation of (±)-Abyssinone II and Its Analogues as Aromatase Inhibitors for Chemoprevention of Breast Cancer

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700266

7 January 2021

Dual aromatase-steroid sulfatase inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700266

7 January 2021

A letrozole-based dual aromatase-sulphatase inhibitor with in vivo activity

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700266

7 January 2021

Dual aromatase-sulfatase inhibitors based on the anastrozole template: synthesis, in vitro SAR, molecular modelling and in vivo activity

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700266

7 January 2021

Imidazole substituted biphenyls: a new class of highly potent and in vivo active inhibitors of P450 17 as potential therapeutics for treatment of prostate cancer

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700266

7 January 2021

Novel imidazolyl and triazolyl substituted biphenyl compounds: synthesis and evaluation as nonsteroidal inhibitors of human 17alpha-hydroxylase-C17, 20-lyase (P450 17)

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700266

7 January 2021

Palladium-Catalyzed Cross-Coupling Reactions of Organoboron Compounds

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700266

7 January 2021

Recent applications of the Suzuki–Miyaura cross-coupling reaction in organic synthesis

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700266

7 January 2021

The impact of microwave synthesis on drug discovery.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700266

7 January 2021

Three-dimensional model of the human aromatase enzyme and density functional parameterization of the iron-containing protoporphyrin IX for a molecular dynamics study of heme-cysteinato cytochromes.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700266

7 January 2021

A three-dimensional model of CYP19 aromatase for structure-based drug design

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700266

7 January 2021

Development and validation of a genetic algorithm for flexible docking

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700266

7 January 2021

Crystal structure of human cytochrome P450 2C9 with bound warfarin

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700266

7 January 2021

Identifiers

DOI

10.1002/CMDC.200700266

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25 December 2017

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25 December 2017