(Q46788822)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24469953%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

title

Reduced ABCG2 and increased SLC22A1 mRNA expression are associated with imatinib response in chronic myeloid leukemia (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24469953%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

main subject

chronic myeloid leukemia

0 references

1 reference

1 reference

6

1 reference

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Elvira M Guerra-Shinohara

6 March 2020

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24469953%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

author name string

Luciene Terezina de Lima

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24469953%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Douglas Vivona

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24469953%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Carolina Tosin Bueno

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24469953%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Rosario D C Hirata

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24469953%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Mario H Hirata

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24469953%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Fabíola Attié de Castro

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24469953%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Maria de Lourdes F Chauffaille

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24469953%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Maria A Zanichelli

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24469953%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Carlos S Chiattone

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24469953%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Vania T M Hungria

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24469953%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

publication date

29 January 2014

1 reference

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6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24469953%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

volume

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24469953%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

issue

3

1 reference

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6 March 2020

page(s)

851

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24469953%20AND%20SRC:MED&resulttype=core&format=json

The impact of gene profiling in chronic myeloid leukaemia

6 March 2020

cites work

1 reference

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21 January 2018

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Chronic imatinib mesylate exposure leads to reduced intracellular drug accumulation by induction of the ABCG2 (BCRP) and ABCB1 (MDR1) drug transport pumps

21 January 2018

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Expression of the uptake drug transporter hOCT1 is an important clinical determinant of the response to imatinib in chronic myeloid leukemia

21 January 2018

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21 January 2018

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Constitutive overexpression of P-glycoprotein, rather than breast cancer resistance protein or organic cation transporter 1, contributes to acquisition of imatinib-resistance in K562 cells

21 January 2018

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Imatinib mesylate is a potent inhibitor of the ABCG2 (BCRP) transporter and reverses resistance to topotecan and SN-38 in vitro

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Functional ABCG2 is overexpressed on primary CML CD34+ cells and is inhibited by imatinib mesylate

21 January 2018

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Role of P-glycoprotein in evolution of populations of chronic myeloid leukemia cells treated with imatinib

21 January 2018

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Effect of interferon-α2b on the expression of various drug-metabolizing enzymes and transporters in co-cultures of freshly prepared human primary hepatocytes

21 January 2018

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Adherence is the critical factor for achieving molecular responses in patients with chronic myeloid leukemia who achieve complete cytogenetic responses on imatinib.

21 January 2018

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Predictors of primary imatinib resistance in chronic myelogenous leukemia are distinct from those in secondary imatinib resistance

21 January 2018

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Impact of early dose intensity on cytogenetic and molecular responses in chronic- phase CML patients receiving 600 mg/day of imatinib as initial therapy

21 January 2018

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21 January 2018

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Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump

21 January 2018

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Comparison of ATP-binding cassette transporter interactions with the tyrosine kinase inhibitors imatinib, nilotinib, and dasatinib

21 January 2018

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Interaction of nilotinib, dasatinib and bosutinib with ABCB1 and ABCG2: implications for altered anti-cancer effects and pharmacological properties

21 January 2018

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Dasatinib targets chronic myeloid leukemia-CD34+ progenitors as effectively as it targets mature cells

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Most CML patients who have a suboptimal response to imatinib have low OCT-1 activity: higher doses of imatinib may overcome the negative impact of low OCT-1 activity

21 January 2018

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OCT-1-mediated influx is a key determinant of the intracellular uptake of imatinib but not nilotinib (AMN107): reduced OCT-1 activity is the cause of low in vitro sensitivity to imatinib

21 January 2018

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