(Q46796677)

25 December 2017

title

A novel PPARalpha agonist ameliorates insulin resistance in dogs fed a high-fat diet (English)

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25 December 2017

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Masaki Tsunoda

1

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25 December 2017

Naoki Kobayashi

2

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25 December 2017

Tomohiro Ide

3

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25 December 2017

Mari Utsumi

4

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25 December 2017

Michiaki Nagasawa

5

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25 December 2017

Koji Murakami

6

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25 December 2017

publication date

22 January 2008

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25 December 2017

American Journal of Physiology - Endocrinology and Metabolism

published in

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25 December 2017

volume

294

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25 December 2017

issue

5

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25 December 2017

page(s)

E833-40

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25 December 2017

Peroxisome proliferator-activated receptor alpha activates transcription of the brown fat uncoupling protein-1 gene. A link between regulation of the thermogenic and lipid oxidation pathways in the brown fat cell.

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Insulin stimulates both leptin secretion and production by rat white adipose tissue

21 January 2018

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Peroxisome proliferator-activated receptor (PPAR)-alpha agonism prevents the onset of type 2 diabetes in Zucker diabetic fatty rats: A comparison with PPAR gamma agonism.

21 January 2018

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The effects of K-111, a new insulin-sensitizer, on metabolic syndrome in obese prediabetic rhesus monkeys

21 January 2018

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Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat

21 January 2018

1 reference

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A ureido-thioisobutyric acid (GW9578) is a subtype-selective PPARalpha agonist with potent lipid-lowering activity

21 January 2018

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Five-hour fatty acid elevation increases muscle lipids and impairs glycogen synthesis in the rat.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPENDO.00627.2007

Long-chain acyl-CoA esters as indicators of lipid metabolism and insulin sensitivity in rat and human muscle.

21 January 2018

1 reference

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Hormonal regulation of adiponectin gene expression in 3T3-L1 adipocytes

21 January 2018

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Obesity wars: molecular progress confronts an expanding epidemic

21 January 2018

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The role of fibric acids in atherosclerosis

21 January 2018

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Drug Insight: mechanisms of action and therapeutic applications for agonists of peroxisome proliferator-activated receptors

21 January 2018

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Peroxisome Proliferator-activated Receptor α Activators Improve Insulin Sensitivity and Reduce Adiposity

21 January 2018

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Tissue-specific actions of antidiabetic thiazolidinediones on the reduced fatty acid oxidation in skeletal muscle and liver of Zucker diabetic fatty rats.

21 January 2018

1 reference

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Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

21 January 2018

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Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial

21 January 2018

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PPAR alpha structure-function relationships derived from species-specific differences in responsiveness to hypolipidemic agents

21 January 2018

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Profiling of adipokines secreted from human subcutaneous adipose tissue in response to PPAR agonists

21 January 2018

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Improvement of glucose tolerance in NIDDM by clofibrate. Randomized double-blind study.

21 January 2018

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Peroxisome proliferator-activated receptor (PPAR)-alpha activation prevents diabetes in OLETF rats: comparison with PPAR-gamma activation

21 January 2018

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Fenofibrate lowers abdominal and skeletal adiposity and improves insulin sensitivity in OLETF rats

21 January 2018

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Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp.

21 January 2018

1 reference

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Highly sensitive upregulation of apolipoprotein A-IV by peroxisome proliferator-activated receptor alpha (PPARalpha) agonist in human hepatoma cells

21 January 2018

1 reference

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Pharmacological characterization of a human-specific peroxisome proliferater-activated receptor alpha (PPARalpha) agonist in dogs

21 January 2018

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Skeletal muscle triglyceride levels are inversely related to insulin action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00627.2007

Maintenance of adiponectin attenuates insulin resistance induced by dietary conjugated linoleic acid in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00627.2007

Muscle triglycerides and mitochondrial function: possible mechanisms for the development of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00627.2007

The peroxisome proliferator activated receptors (PPARS) and their effects on lipid metabolism and adipocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00627.2007

Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men.

21 January 2018

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Mechanism of action of fibrates on lipid and lipoprotein metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00627.2007

Conversion of human-selective PPARalpha agonists to human/mouse dual agonists: a molecular modeling analysis

21 January 2018

1 reference

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The PPARs: from orphan receptors to drug discovery

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPENDO.00627.2007

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

21 January 2018

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10.1152/AJPENDO.00627.2007

21 January 2018

Identifiers

DOI

1 reference

25 December 2017

PubMed ID

18212024

1 reference

25 December 2017