(Q46798860)

http://europepmc.org/abstract/MED/16280588

25 December 2017

title

Silencing primary dystonia: lentiviral-mediated RNA interference therapy for DYT1 dystonia (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725832&resulttype=core&format=json

12 May 2020

1 reference

Pedro Gonzalez-Alegre

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725832&resulttype=core&format=json

12 May 2020

Nicole Bode

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725832&resulttype=core&format=json

12 May 2020

Beverly L Davidson

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725832&resulttype=core&format=json

12 May 2020

Henry L Paulson

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725832&resulttype=core&format=json

12 May 2020

language of work or name

English

0 references

publication date

1 November 2005

1 reference

http://europepmc.org/abstract/MED/16280588

25 December 2017

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725832&resulttype=core&format=json

12 May 2020

volume

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725832&resulttype=core&format=json

12 May 2020

issue

45

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725832&resulttype=core&format=json

12 May 2020

page(s)

10502-10509

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725832&resulttype=core&format=json

Mutant torsinA, responsible for early-onset torsion dystonia, forms membrane inclusions in cultured neural cells

12 May 2020

cites work

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12 December 2020

Torsin A and its torsion dystonia-associated mutant forms are lumenal glycoproteins that exhibit distinct subcellular localizations

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12 December 2020

TorsinA: movement at many levels

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12 December 2020

Functional correction of established central nervous system deficits in an animal model of lysosomal storage disease with feline immunodeficiency virus-based vectors

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12 December 2020

Viral vectors for gene delivery to the nervous system

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12 December 2020

Toward therapy for DYT1 dystonia: allele-specific silencing of mutant TorsinA

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12 December 2020

Induction of an interferon response by RNAi vectors in mammalian cells

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12 December 2020

Culturing hippocampal and cortical neurons

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12 December 2020

Activation of the interferon system by short-interfering RNAs

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12 December 2020

Mouse models of torsinA dysfunction

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12 December 2020

Developments in the molecular biology of DYT1 dystonia

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12 December 2020

Asymmetry in the assembly of the RNAi enzyme complex

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12 December 2020

Functional siRNAs and miRNAs Exhibit Strand Bias

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12 December 2020

Approaches for the sequence-specific knockdown of mRNA.

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12 December 2020

Mislocalization to the nuclear envelope: an effect of the dystonia-causing torsinA mutation.

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12 December 2020

Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells

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12 December 2020

Molecular medicine for the brain: silencing of disease genes with RNA interference

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12 December 2020

Aberrant cellular behavior of mutant torsinA implicates nuclear envelope dysfunction in DYT1 dystonia.

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12 December 2020

Determinants of interferon-stimulated gene induction by RNAi vectors

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12 December 2020

TorsinA in the nuclear envelope

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12 December 2020

Sfold web server for statistical folding and rational design of nucleic acids

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12 December 2020

RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia.

1 reference

12 December 2020

Short-term cytotoxic effects and long-term instability of RNAi delivered using lentiviral vectors

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12 December 2020

Revealing the world of RNA interference

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12 December 2020

Therapeutic potential of RNA interference

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12 December 2020

Effect of torsinA on membrane proteins reveals a loss of function and a dominant-negative phenotype of the dystonia-associated DeltaE-torsinA mutant

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12 December 2020

Lack of interferon response in animals to naked siRNAs

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12 December 2020

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

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12 December 2020

Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS.

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12 December 2020

Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model

1 reference

12 December 2020

Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA

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12 December 2020

RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model

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12 December 2020

Impaired motor learning in mice expressing torsinA with the DYT1 dystonia mutation.

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12 December 2020

AAA+ proteins: have engine, will work

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12 December 2020

The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein

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12 December 2020

Classification of dystonia

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12 December 2020

10.1523/JNEUROSCI.3016-05.2005

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725832&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725832&resulttype=core&format=json

12 May 2020

1 reference