(Q46807655)

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Modulation of expression of rat mitochondrial 2-oxoglutarate carrier in NRK-52E cells alters mitochondrial transport and accumulation of glutathione and susceptibility to chemically induced apoptosis

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scholarly article

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Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16291728

Modulation of expression of rat mitochondrial 2-oxoglutarate carrier in NRK-52E cells alters mitochondrial transport and accumulation of glutathione and susceptibility to chemically induced apoptosis (English)

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16291728

1 reference

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Lawrence H. Lash

4

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16291728

author name string

Feng Xu

1

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16291728

David A Putt

2

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16291728

Larry H Matherly

3

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Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16291728

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publication date

15 November 2005

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Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16291728

Journal of Pharmacology and Experimental Therapeutics

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Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16291728

316

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Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16291728

1175-1186

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Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16291728

3

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16291728

Enrichment and functional reconstitution of glutathione transport activity from rabbit kidney mitochondria: further evidence for the role of the dicarboxylate and 2-oxoglutarate carriers in mitochondrial glutathione transport

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https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

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Cellular and subcellular heterogeneity of glutathione metabolism and transport in rat kidney cells

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https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis, necrosis, and cell proliferation induced by S-(1,2-dichlorovinyl)-L-cysteine in primary cultures of human proximal tubular cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

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Toxic, halogenated cysteine S-conjugates and targeting of mitochondrial enzymes of energy metabolism

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https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

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Protection of NRK-52E cells, a rat renal proximal tubular cell line, from chemical-induced apoptosis by overexpression of a mitochondrial glutathione transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

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Cellular energetics and glutathione status in NRK-52E cells: toxicological implications.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

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Early oxidative stress in the diabetic kidney: effect of DL-alpha-lipoic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

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inferred from PubMed ID database lookup

Tumor cytotoxicity by endothelial cells. Impairment of the mitochondrial system for glutathione uptake in mouse B16 melanoma cells that survive after in vitro interaction with the hepatic sinusoidal endothelium.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

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Sensitivity of the 2-oxoglutarate carrier to alcohol intake contributes to mitochondrial glutathione depletion

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mitochondrial pyruvate carrier. Kinetics and specificity for substrates and inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of glutathione in the retention of Ca2+ by liver mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thiols in oxidative phosphorylation: inhibition and energy-potentiated uncoupling by monothiol and dithiol modifiers

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crucial role of sulfhydryl groups in the mitochondrial inner membrane structure

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Origin and turnover of mitochondrial glutathione

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

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Purification of reconstitutively active alpha-oxoglutarate carrier from pig heart mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of S-(1,2-dichlorovinyl)glutathione-induced nephrotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of S-(1,2-dichlorovinyl)-L-cysteine- and S-(1,2-dichlorovinyl)-L-homocysteine-induced renal mitochondrial toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and reconstitution of two anion carriers from rat liver mitochondria: The dicarboxylate and the 2-oxoglutarate carrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular distribution and depletion of glutathione in rabbit renal proximal tubules

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial damage in muscle occurs after marked depletion of glutathione and is prevented by giving glutathione monoester

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cysteine conjugate toxicity, metabolism, and binding to macromolecules in isolated rat kidney mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione: toxicological implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renal mitochondrial glutathione transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uptake of glutathione by renal cortical mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced activity of the electron transport chain in liver mitochondria isolated from rats with secondary biliary cirrhosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective depletion of mitochondrial glutathione concentrations by (R,S)-3-hydroxy-4-pentenoate potentiates oxidative cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial glutathione depletion in alcoholic liver disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of the rat-liver mitochondrial dicarboxylate carrier by affinity chromatography on immobilized malate dehydrogenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and sequencing of the rat cDNA encoding the mitochondrial 2-oxoglutarate carrier protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced antioxidative capacity in liver mitochondria from bile duct ligated rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of succinate:ubiquinone reductase and decrease of ubiquinol in nephrotoxic cysteine S-conjugate-induced oxidative cell injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial metabolite transporters.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compartmentation of glutathione: implications for the study of toxicity and disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a novel gene encoding the yeast mitochondrial dicarboxylate transport protein via overexpression, purification, and characterization of its protein product

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GSH transport in mitochondria: defense against TNF-induced oxidative stress and alcohol-induced defect.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mitochondrial death/life regulator in apoptosis and necrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for mitochondrial uptake of glutathione by dicarboxylate and 2-oxoglutarate carriers

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The sequence, bacterial expression, and functional reconstitution of the rat mitochondrial dicarboxylate transporter cloned via distant homologs in yeast and Caenorhabditis elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the human mitochondrial oxodicarboxylate carrier. Bacterial expression, reconstitution, functional characterization, tissue distribution, and chromosomal location

1 reference

https://pubmed.ncbi.nlm.nih.gov/16291728

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1124/JPET.105.094599

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16291728

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/16291728

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