(Q46817719)

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Vascular endothelial growth factor protects spinal cord motoneurons against glutamate-induced excitotoxicity via phosphatidylinositol 3-kinase.

scientific article published on 25 December 2007

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31 December 2019

Vascular endothelial growth factor protects spinal cord motoneurons against glutamate-induced excitotoxicity via phosphatidylinositol 3-kinase (English)

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31 December 2019

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31 December 2019

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31 December 2019

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Margalida Mir

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31 December 2019

Víctor J Asensio

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31 December 2019

Jerònia Lladó

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31 December 2019

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25 December 2007

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31 December 2019

Journal of Neurochemistry

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31 December 2019

105

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31 December 2019

1080-1090

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31 December 2019

4

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31 December 2019

Increased motoneuron survival and improved neuromuscular function in transgenic ALS mice after intraspinal injection of an adeno-associated virus encoding Bcl-2.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

VEGF mRNA induction correlates with changes in the vascular architecture upon spinal cord damage in the rat.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

VEGF upregulates Bcl-2 expression and is associated with decreased apoptosis in neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

VEGF-mediated survivin expression in neuroblastoma cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

ALS: a disease of motor neurons and their nonneuronal neighbors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

Onset and progression in inherited ALS determined by motor neurons and microglia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

IAP family proteins--suppressors of apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

Activation of phosphatidylinositol 3-kinase, but not extracellular-regulated kinases, is necessary to mediate brain-derived neurotrophic factor-induced motoneuron survival.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MAPK/ERK and SAPK/JNK signaling

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

Neuroprotective effects of bcl-2 overexpression in hippocampal cultures: interactions with pathways of oxidative damage.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

Induction of VEGF and its Flt-1 receptor after sciatic nerve crush injury.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

Essential role for survivin in early brain development

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

Vascular endothelial growth factor: direct neuroprotective effect in in vitro ischemia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

The phosphatidylinositol-3 kinase/Akt pathway mediates VEGF's neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

VEGF at the neurovascular interface: therapeutic implications for motor neuron disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

VEGF-induced activation of the PI3-K/Akt pathway reduces mutant SOD1-mediated motor neuron cell death.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

Neural stem cells protect against glutamate-induced excitotoxicity and promote survival of injured motor neurons through the secretion of neurotrophic factors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

Suppression of vascular endothelial growth factor-mediated endothelial cell protection by survivin targeting.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

A novel vascular endothelial growth factor encoded by Orf virus, VEGF-E, mediates angiogenesis via signalling through VEGFR-2 (KDR) but not VEGFR-1 (Flt-1) receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

Paracrine and autocrine functions of neuronal vascular endothelial growth factor (VEGF) in the central nervous system

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

Reduction of a vascular endothelial growth factor receptor, fetal liver kinase-1, by antisense oligonucleotides induces motor neuron death in rat spinal cord exposed to hypoxia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

Vascular, glial and neuronal effects of vascular endothelial growth factor in mesencephalic explant cultures.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

Vascular endothelial growth factor protects cultured rat hippocampal neurons against hypoxic injury via an antiexcitotoxic, caspase-independent mechanism

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

Vascular endothelial growth factor overexpression delays neurodegeneration and prolongs survival in amyotrophic lateral sclerosis mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

BCL-2 blocks glutamate toxicity in neural cell lines

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

Vascular endothelial growth factor counteracts the loss of phospho-Akt preceding motor neurone degeneration in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

Effects of vascular endothelial growth factor (VEGF) on motor neuron degeneration

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

Cell-Specific Upregulation of Survivin after Experimental Traumatic Brain Injury in Rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05206.X

21 January 2018

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10.1111/J.1471-4159.2007.05206.X

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Europe PubMed Central

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31 December 2019

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24 November 2022

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31 December 2019

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